Results 211 to 220 of about 311,268 (263)

Antibody-Dependent Cell-Mediated Cytotoxicity Against Influenza Virus-Infected Cells

Journal of Infectious Diseases, 1983
The three major immunocompetent cells in human peripheral blood (lymphocytes, neutrophils, and monocytes) were shown to be effector cells for antibody-dependent cell-mediated cytotoxicity (ADCC) against influenza virus-infected baby hamster kidney cells in vitro.
G, Hashimoto, P F, Wright, D T, Karzon
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Antibody-dependent cell-mediated cytotoxicity for cultured autologous melanoma cells

Cellular Immunology, 1981
Abstract Sera from 33 patients with malignant melanoma were tested for antibody-dependent cellmediated cytotoxicity (ADCC) against cultured autologous melanoma cells prelabeled with [ 3 H]proline in a 36-h assay. Effector cells (autologous or from normal donors) were obtained by Ficoll-Hypaque separation of peripheral blood.
P O, Livingston, R, Michitsch, H, Shiku, C M, Pinsky, H F, Oettgen   +4 more
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Antibody‐dependent cell cytotoxicity: immunotherapy strategies enhancing effector NK cells

Immunology & Cell Biology, 2017
Antibody‐dependent cellular cytotoxicity (ADCC) is a set of mechanisms that target cells coated with IgG antibodies of the proper subclasses (IgG1 in the human) to be the prey of cell‐to‐cell cytolysis executed by immune cells expressing FcRIIIA (CD16A).
Maria Carmen, Ochoa, Luna, Minute, Inmaculada, Rodriguez, Saray, Garasa, Elisabeth, Perez-Ruiz, Susana, Inogés, Ignacio, Melero, Pedro, Berraondo   +7 more
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Different effector cell types in antibody-dependent cell-mediated cytotoxicity

Nature, 1975
ANTIBODY-DEPENDENT cell-mediated cytotoxicity has been demonstrated in vitro using a number of continuously cultivated cell lines1,2 and nucleated erythrocytes3 as targets. Although the biological role of this cytotoxicity is not yet clear, it represents a potentially efficient cytotoxic mechanism and considerable interest has been shown in the ...
C J, Sanderson, I A, Clark, G A, Taylor
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Antibody-dependent cell-mediated cytotoxicity (ADCC) in Aujeszky's disease

Archives of Virology, 1979
Antibody-dependent cell-mediated cytotoxicity (ADCC) was studied using as targets 51Cr-labelled Vero cells infected with the Bartha strain of Aujeszky's disease virus (ADV). Using hyperimmune anti-ADV serum to sensitize the targets, porcine leukocytes from dextran-sedimented blood were found to be efficient effector cells yielding maximal 51Cr release ...
L A, Ashworth, G, Lloyd, A, Baskerville
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Antibody-dependent cell-mediated cytotoxicity

AIDS, 1988
This study confirms the presence of detectable antibody-dependent cell-mediated cytotoxicity (ADCC) towards both HTLV-I- and HIV-1-infected cell lines, mediated by normal donor peripheral blood mononuclear cells and either by antibody from adult T-cell lymphoma and tropical spastic paraparesis patients (HTLV-I) or by antibody from sera of patients with
A L, Sinclair, J A, Habeshaw, L, Muir, P, Chandler, S, Forster, K, Cruickshank, A G, Dalgleish   +6 more
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Antibody-Dependent Cellular Cytotoxicity Effector Cells Lack Ia Antigens

The Journal of Immunology, 1977
Abstract Surface immunoglobulin (sIg)-positive and sIg-negative subpopulations of macrophage-depleted murine splenic lymphocytes were obtained by Sephadex anti-Fab immunoabsorbent fractionation. These lymphocyte subpopulations were analyzed for the presence of Thy 1 and Ia alloantigens and also for Fc receptors by fluorescence microscopy.
Nelson, D L, Sachs, D H, Dickler, H B
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Antibody-Dependent Lymphoid Cell-Mediated Cytotoxicity: Role of Complement

The Journal of Immunology, 1974
Abstract Unsensitized lymphoid cells have the capacity to destroy antibody-coated target cells in vitro. Definitive studies to rule out the participation of complement (C) components in this reaction require a system with a complete absence of C components and with no possibility of endogenous synthesis of C by cells in culture.
J A, Van Boxel, W E, Paul, I, Green, M M, Frank   +3 more
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Antibody-dependent Cytotoxicity to Transitional Cells in Cystitis Cystica

Journal of Urology, 1981
Serum from 20 children with urinary tract infections and proved cystitis cystica has been examined for antibody to a panel of established cell lines derived from normal urothelium and transitional cell carcinomas of the bladder. Antibody-dependent cytotoxicity was measured with serial dilutions of patient serum and lymphocytes from normal healthy ...
H N, Noe, E F, Burkhardt, G R, Jerkins, C, O'Toole   +3 more
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Evaluating Antibody-Dependent Cell-Mediated Cytotoxicity by Flow Cytometry

2019
Antibody-dependent cell-mediated cytotoxicity (ADCC) is a mechanism in which immune cell activation is induced by the cross-linking of CD16 with the Fc region of antibodies that at the same time bind specifically to cell surface antigens. ADCC stimulates the secretion of perforin, granzymes, and cytokines leading to lysis of the malignant cells ...
Irene, van der Haar Àvila, Patricia, Marmol, Jeannette, Cany, Rolf, Kiessling, Yago, Pico de Coaña   +4 more
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