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Rituximab in Connective Tissue Disease-Associated Interstitial Lung Disease: From Immunopathogenesis to Therapeutic Implications. [PDF]
Chatzis D +4 more
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CD40L and IL-4 lymph node-associated signals protect B cells from rituximab-induced ADCC via KIR and NKG2A. [PDF]
Graham LV +8 more
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Antibody-dependent cell-mediated cytotoxicity (ADCC)in liver diseases
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Antibody-Dependent Cell-Mediated Cytotoxicity
The Journal of Immunology, 1974Abstract Macrophages obtained from peritoneal exudate are effector cells for antibody-dependent cytotoxicity. This effector function is independent of phagocytosis, and it is not inhibited by EDTA or aminophylline. Cells functionally similar to those in peritoneal exudate can be obtained from the spleen, but a functionally different ...
Juan Carlos Scornik, Humberto Cosenza
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Complement enhances antiviral antibody-dependent cell cytotoxicity
Nature, 1977ANTIBODY-DEPENDENT cell cytotoxicity (ADCC) is an in vitro phenomenon that can be demonstrated with a variety of target cell systems and can be mediated by several types of effector cells1–3. The effectors in ADCC must bear a surface receptor for Fc, and this receptor binds with antibody which is in turn bound to the target cell.
B T, Rouse, A S, Grewal, L A, Babiuk
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Antibody-dependent cell-mediated cytotoxicity in pigs
American Journal of Veterinary Research, 1982SUMMARY Development of antibody-dependent cell-mediated cytotoxicity (adcc) was studied in cells obtained from porcine fetal and neonatal tissues. Pulmonary washouts, hepatic tissues, splenic tissues, and neutrophil fractions of blood were sources of cells.
A, Zarkower +4 more
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Human lymphoblast cell lines: Antibody‐dependent cytotoxicity
European Journal of Immunology, 1975AbstractFive cell lines were isolated after prolonged culture of human buffy coat leukocytes. The cells consisted for the most part of lymphoblasts morphologically similar to those produced by in vivo or in vitro stimulation of small lymphocytes by antigens or mitogens. One of the lines possessed virus‐like particles of the Epstein‐Barr type.
J C, Lefebre +3 more
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Enzymatic Enhancement of Cell-Mediated Cytotoxicity and Antibody-Dependent Cell Cytotoxicity
The Journal of Immunology, 1974Abstract The effects of papain, trypsin, Pronase, neuraminidase, and phospholipase C on in vitro cell-mediated cytotoxicity (CMC) and antibody-dependent cell cytotoxicity (ADCC) have been studied in a syngeneic tumor system. Proteolytic enzyme treatment of lymphoid (effector) cells at low concentrations (<0.1 mg/ml) and for short ...
E, Kedar +2 more
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