Potential Neutralizing Antibodies Discovered for Novel Corona Virus Using Machine Learning [PDF]
arXiv, 2020 The fast and untraceable virus mutations take lives of thousands of people before the immune system can produce the inhibitory antibody. Recent outbreak of novel coronavirus infected and killed thousands of people in the world. Rapid methods in finding peptides or antibody sequences that can inhibit the viral epitopes of COVID-19 will save the life of ...
arxiv
Therapeutic efficacy of anti-MMP9 antibody in combination with nab-paclitaxel-based chemotherapy in pre-clinical models of pancreatic cancer [PDF]
, 2019 Matrix metalloproteinase 9 (MMP9) is involved in the proteolysis of extracellular proteins and plays a critical role in pancreatic ductal adenocarcinoma (PDAC) progression, invasion and metastasis.
Awasthi, Niranjan +6 more
core +1 more source
The whole genomic analysis of orf virus strain HN3/12 isolated from Henan province, central China
BMC Veterinary Research, 2017 Background The Orf virus (ORFV) is the causative agent of orf, a globally-occurring, acute, pustular, contagious disease affecting sheep, goats and humans with a worldwide distribution. Currently, the genomic analysis of four ORFV strains from the Fujian
Huiqin Chen +7 more
doaj +1 more source
Nanoparticles for live cell microscopy: A surface-enhanced Raman scattering perspective. [PDF]
, 2017 Surface enhanced Raman scattering (SERS) nanoparticles are an attractive alternative to fluorescent probes for biological labeling because of their photostability and multiplexing capabilities.
Candas, Demet +7 more
core +1 more source
mAbs, 2022 Controlled Fab arm exchange (cFAE) has proven to be a generic and versatile technology for the efficient generation of IgG-like bispecific antibodies (DuoBodies or DBs), with several in clinical development and one product, amivantamab, approved by the ...
Desislava Yanakieva +9 more
doaj +1 more source
Regioselective and stoichiometrically controlled conjugation of photodynamic sensitizers to a HER2 targeting antibody fragment [PDF]
, 2014 The rapidly increasing interest in the synthesis of antibody–drug conjugates as powerful targeted anticancer agents demonstrates the growing appreciation of the power of antibodies and antibody fragments as highly selective targeting moieties.
Boyle, Ross W. +6 more
core +1 more source
Evaluating pre-treatment methods in the isolation and purification of monoclonal IgG antibody [PDF]
, 2008 In this study, the effects of different sample preparation techniques on the separation of monoclonal antibody IgG I were inve st igated experimentally. Monoclonal IgG I was obtained from hybridoma cell line TB /C3 transfected with bcl-2 carrier plasmid.
Abdul Majid, Fadzilah Adibah +1 more
core
Development of an antibody fragment that stabilizes GPCR/G-protein complexes. [PDF]
, 2018 Single-particle cryo-electron microscopy (cryo-EM) has recently enabled high-resolution structure determination of numerous biological macromolecular complexes.
Dawson, Roger JP +9 more
core +2 more sources
CLEC14a-HSP70-1A interaction regulates HSP70-1A-induced angiogenesis
Scientific Reports, 2017 CLEC14a (C-type lectin domain family 14 member) is a tumor endothelial cell marker protein that is known to play an important role in tumor angiogenesis, but the basic molecular mechanisms underlying this function have not yet been clearly elucidated. In
Jihye Jang +6 more
doaj +1 more source
Effect of antibody levels on the spread of disease in multiple infections [PDF]
There are complex interactions between antibody levels and epidemic propagation, the antibody level of an individual influences the probability of infection, and the spread of the virus influences the antibody level of each individual. There exist some viruses that, in their natural state, cause antibody levels in an infected individual to gradually ...
arxiv +1 more source