Results 11 to 20 of about 1,020,846 (330)

Prevalence and clinical implications of anti-drug antibody formation and serum drug levels among patients with IBD receiving anti-TNF therapy: A cross-sectional study [PDF]

The Saudi Journal of Gastroenterology
Background: The emergence of tumor necrosis factor inhibitors (anti-TNF) has considerably changed the management of inflammatory bowel disease (IBD) in patients who do not respond to traditional therapies.
Ahmed Alghamdi, Mohammed Alahmari, Khulood Aljohani, Aisha Alanazi, Bashaar Al Ibrahim, Mishal Alshowair, Marwa Tawfik, Waleed Alghamdi, Salman Alanazi, Faisal Alzayed, Abdullah S Alghamdi, Abdullah Bawazir, Hussam Alhamidi   +12 more
doaj   +2 more sources

Lentiviral gene therapy prevents anti-human acid α-glucosidase antibody formation in murine Pompe disease [PDF]

Molecular Therapy: Methods & Clinical Development, 2022
Enzyme replacement therapy (ERT) is the current standard treatment for Pompe disease, a lysosomal storage disorder caused by deficiency of the lysosomal enzyme acid alpha-glucosidase (GAA).
Qiushi Liang, Eva C. Vlaar, Fabio Catalano, Joon M. Pijnenburg, Merel Stok, Yvette van Helsdingen, Arnold G. Vulto, Wendy W.J. Unger, Ans T. van der Ploeg, W.W.M. Pim Pijnappel, Niek P. van Til   +10 more
doaj   +2 more sources

Fc Gamma Receptors and Complement Component 3 Facilitate Anti-fVIII Antibody Formation [PDF]

Frontiers in Immunology, 2020
Anti-factor VIII (fVIII) alloantibodies, which can develop in patients with hemophilia A, limit the therapeutic options and increase morbidity and mortality of these patients.
Patricia E. Zerra, Patricia E. Zerra, Connie M. Arthur, Satheesh Chonat, Cheryl L. Maier, Amanda Mener, Sooncheon Shin, Jerry William L. Allen, W. Hunter Baldwin, Courtney Cox, Hans Verkerke, Ryan P. Jajosky, Christopher A. Tormey, Christopher A. Tormey, Shannon L. Meeks, Sean R. Stowell   +15 more
doaj   +2 more sources

Environmental Triggers of Autoreactive Responses: Induction of Antiphospholipid Antibody Formation [PDF]

Frontiers in Immunology, 2019
Antiphospholipid antibodies (aPLs) comprise a diverse family of autoantibodies targeted against proteins with the affinity toward negatively charged phospholipids or protein-phospholipid complexes.
Anush Martirosyan, Anush Martirosyan, Rustam Aminov, Gayane Manukyan, Gayane Manukyan   +4 more
doaj   +2 more sources

Measles vaccination in children with neurological disorders

Журнал инфектологии, 2014
The data on the current vaccination process and specific antibody in 212 children with pathology of nervous systems in age from 1 year to 6 years old, vaccinated against measles. The comparison group consisted of 36 children without neurological disease.
S. P. Kaplina, S. M. Kharit, O. V. Goleva, E. I. Aleksandrova   +3 more
doaj   +1 more source

ANTIBODY FORMATION IN VITRO [PDF]

The Journal of Experimental Medicine, 1961
Neutralizing activity against T2 bacteriophage appeared in cultures of lymph node cells from normal rats in response to their in vitro stimulation with a cell-free filtrate derived from homogenized rat macrophages which had been incubated with T2 bacteriophage. This activity was specifically directed against T2 bacteriophage.
openaire   +3 more sources

A Role for the Transcription Factor Arid3a in Mouse B2 Lymphocyte Expansion and Peritoneal B1a Generation

Frontiers in Immunology, 2017
The initiation, commitment, and terminal differentiation of the B cell lineage is stringently controlled by the coordinated action of various transcription factors.
Katrin Habir, Shahin Aeinehband, Fredrik Wermeling, Stephen Malin   +3 more
doaj   +1 more source

Prevalência de aloimunização eritrocitária em pacientes portadores de anemia falciforme

ABCS Health Sciences, 2017
Embora as transfusões de concentrado de hemácias sejam importantes para o tratamento de pacientes com anemia falciforme, elas acarretam riscos imunológicos tais como a aloimunização a antígenos eritrocitários.
Alexandre Gomes Vizzoni, Heladya Maria Matos Moreira   +1 more
doaj   +1 more source

Low disease activity of microscopic polyangiitis in patients with anti-myosin light chain 6 antibody that disrupts actin rearrangement necessary for neutrophil extracellular trap formation

Arthritis Research & Therapy, 2022
Background Neutrophil extracellular traps (NETs) are critically involved in microscopic polyangiitis (MPA) pathogenesis, and some patients with MPA possess anti-NET antibody (ANETA). Anti-myosin light chain 6 (MYL6) antibody is an ANETA that affects NETs.
Miku Yoshinari, Yuka Nishibata, Sakiko Masuda, Daigo Nakazawa, Utano Tomaru, Yoshihiro Arimura, Koichi Amano, Yukio Yuzawa, Ken-Ei Sada, Tatsuya Atsumi, Hiroaki Dobashi, Hitoshi Hasegawa, Masayoshi Harigai, Seiichi Matsuo, Hirofumi Makino, Akihiro Ishizu   +15 more
doaj   +1 more source

THE ANTIBODY-FORMATION BY POLYSACCHARIDS [PDF]

Journal of Experimental Medicine, 1929
1. By complement fixation tests, it has been clearly demonstrated that the sera of rabbits immunized with inulin, soluble starch and dextrine contain specific antibodies. 2. All these immune sera gave a negative precipitation reaction. 3.
openaire   +3 more sources