Results 11 to 20 of about 447,696 (288)

A Polar Sulfamide Spacer Significantly Enhances the Manufacturability, Stability, and Therapeutic Index of Antibody–Drug Conjugates

open access: yesAntibodies, 2018
Despite tremendous efforts in the field of targeted cancer therapy with antibody–drug conjugates (ADCs), attrition rates have been high. Historically, the priority in ADC development has been the selection of target, antibody, and toxin, with little ...
Jorge M. M. Verkade   +5 more
doaj   +5 more sources

Impact of COVID-19 on Cytomegalovirus Immunoglobulin M Antibody Index

open access: yesClinical and Experimental Obstetrics & Gynecology, 2023
Background: Coronavirus disease 2019 (COVID-19) influenced the prevalence of other infectious diseases, including congenital cytomegalovirus (CMV) infection. However, the effect of COVID-19 on antibody titers has not been reported.
Masatoki Kaneko   +4 more
doaj   +3 more sources

The Association of Antibody Levels with Body Mass Index, Stress Management Ability and Lipid Peroxidation in Patients with Hashimoto’s Thyroiditis

open access: yesThe Turkish Journal of Ear Nose and Throat, 2023
Objective: The potential predictive value of body mass index, stress management ability, and thiobarbituric acid reactive substances (TBARS) levels for antibody levels in Hashimoto’s thyroiditis (HT) were evaluated.Materials and Methods: Two hundred ...
Murat Giriş   +6 more
doaj   +2 more sources

Antibody Index In Neuroimmunoepidemiological Studie

open access: yesRevista Cubana de Investigaciones Biomédicas, 2019
The evaluation of the neuroimmunoepidemiological response from the reibergram allows the determination of the specific antibody index for a determined etiological agent.
Eneida Barrios-Lamoth   +1 more
doaj   +1 more source

Antibody indexes in COVID-19 convalescent plasma donors: Unanswered questions

open access: yesClinics, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is characterized by high contagiousness, as well as variable clinical manifestations and immune responses. The antibody response to SARS-CoV-2 is directly related to viral clearance and the antibodies' ability to neutralize the virus and confer long-term immunity.
Tatiana Carvalho de Souza Bonetti   +9 more
openaire   +6 more sources

The role of antibody indexes in clinical virology [PDF]

open access: yesClinical Microbiology and Infection, 2021
Serological techniques are an essential part of the diagnostic tools used in clinical virology. Among these techniques, antibody indexes are not novel, but do require specific expertise. Their niche has expanded substantially in recent years due to increasing evidence of their performance to diagnose viral infections.This narrative review describes the
Marc C, Shamier   +7 more
openaire   +4 more sources

Aqueous Humor Analysis in Overlapping Clinical Diagnosis of Cytomegalovirus and Rubella Virus Anterior Uveitis

open access: yesMedicina, 2022
Background and Objectives: A cross-sectional single-center study was conducted to investigate the etiology in hypertensive anterior uveitis whose clinical features are not fully distinctive from cytomegalovirus or from rubella virus and to demonstrate ...
Fabrizio Gozzi   +13 more
doaj   +1 more source

Retrospective Evaluation of Various Serological Assays and Multiple Parameters for Optimal Diagnosis of Lyme Neuroborreliosis in a Routine Clinical Setting

open access: yesMicrobiology Spectrum, 2022
Laboratory diagnosis of Lyme neuroborreliosis (LNB) is challenging, and validated diagnostic algorithms are lacking. Therefore, this retrospective cross-sectional study aimed to compare the diagnostic performance of seven commercial antibody assays for ...
Tamara van Gorkom   +7 more
doaj   +1 more source

RESISTANCE OF FOUR DIFFERENT LOCAL HYBRID CHICKENS TO INFECTIOUS BURSAL DISEASE INFECTION

open access: yesThe Iraqi Journal of Veterinary Medicine, 2021
Four hundred, one day old chicks, of four hybrids, were divided into four groups, reared on the floor for ten weeks. The hybrids were vaccinated with live IBD vaccine at 14, 35, 56 days. Maternal antibody titers, antibody titer after each vaccination and
M. A. Al-Zuhairy
doaj   +1 more source

Improved method to calculate the antibody avidity index [PDF]

open access: yesJournal of Clinical Laboratory Analysis, 2007
AbstractThe methods currently used to determine the immunoglobulin avidity index (AI) require the choice of a reference point in the ELISA titration curve. Since both curves, with and without denaturating reagents, seldom run in parallel, the AI value becomes highly dependent on this reference.
C T, Perciani   +4 more
openaire   +2 more sources

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