Results 11 to 20 of about 6,557,782 (278)

The role of antibody indexes in clinical virology [PDF]

open access: yesClinical Microbiology and Infection, 2021
Serological techniques are an essential part of the diagnostic tools used in clinical virology. Among these techniques, antibody indexes are not novel, but do require specific expertise. Their niche has expanded substantially in recent years due to increasing evidence of their performance to diagnose viral infections.This narrative review describes the
Maarten J. Titulaer   +2 more
exaly   +5 more sources

Anti-John Cunningham virus antibody index levels in multiple sclerosis patients treated with rituximab, fingolimod, and dimethyl fumarate. [PDF]

open access: yesSurg Neurol Int, 2019
Background: Progressive multifocal leukoencephalopathy (PML), a potentially fatal demyelinating disease caused by the John Cunningham virus (JCV), can occur as a complication of treatment with rituximab, fingolimod, and dimethyl fumarate.
Farley S   +7 more
europepmc   +2 more sources

Longitudinal analyses of anti-JCV antibody index for risk assessment of progressive multifocal leukoencephalopathy. [PDF]

open access: yesMult Scler J Exp Transl Clin, 2016
Risk assessment for natalizumab-associated progressive multifocal leukoencephalopathy (Nat-PML) comprises the anti-JC virus (JCV) antibody index (AI). The anti-JCV AI was longitudinally determined in a natalizumab-treated MS cohort (Nat-MS, n = 468) and ...
Salmen A   +8 more
europepmc   +2 more sources

The clinical utility of JC virus antibody index measurements in the context of progressive multifocal leukoencephalopathy

open access: yesActa Neurologica Scandinavica, 2017
In natalizumab‐treated patients without previous immunosuppressive treatment, the JCV antibody index is used to stratify PML risk. A high index value indicates that the risk to develop PML is significantly elevated, although probably about 99% of ...
Tilman Schneider-Hohendorf   +1 more
exaly   +2 more sources

Antibody Index In Neuroimmunoepidemiological Studie

open access: yesRevista Cubana de Investigaciones Biomédicas, 2019
The evaluation of the neuroimmunoepidemiological response from the reibergram allows the determination of the specific antibody index for a determined etiological agent.
Eneida Barrios-Lamoth   +1 more
doaj   +1 more source

Antibody index and specific antibody quotient in horses after intragastric administration of Sarcocystis neurona sporocysts.

open access: yesAmerican Journal of Veterinary Research, 2008
Abstract Objective—To investigate the use of a specific antibody index (AI) that relates Sarcocystis neurona–specific IgG quotient (QSN) to total IgG quotient (QIgG) for the detection of the anti–S neurona antibody fraction of CNS origin in CSF samples obtained from horses after intragastric administration of S neurona sporocysts.
K. Heskett, R. MacKay
semanticscholar   +3 more sources

A Polar Sulfamide Spacer Significantly Enhances the Manufacturability, Stability, and Therapeutic Index of Antibody–Drug Conjugates

open access: yesAntibodies, 2018
Despite tremendous efforts in the field of targeted cancer therapy with antibody–drug conjugates (ADCs), attrition rates have been high. Historically, the priority in ADC development has been the selection of target, antibody, and toxin, with little ...
Jorge M. M. Verkade   +5 more
doaj   +3 more sources

Retrospective Evaluation of Various Serological Assays and Multiple Parameters for Optimal Diagnosis of Lyme Neuroborreliosis in a Routine Clinical Setting

open access: yesMicrobiology Spectrum, 2022
Laboratory diagnosis of Lyme neuroborreliosis (LNB) is challenging, and validated diagnostic algorithms are lacking. Therefore, this retrospective cross-sectional study aimed to compare the diagnostic performance of seven commercial antibody assays for ...
Tamara van Gorkom   +7 more
doaj   +1 more source

Aqueous Humor Analysis in Overlapping Clinical Diagnosis of Cytomegalovirus and Rubella Virus Anterior Uveitis

open access: yesMedicina, 2022
Background and Objectives: A cross-sectional single-center study was conducted to investigate the etiology in hypertensive anterior uveitis whose clinical features are not fully distinctive from cytomegalovirus or from rubella virus and to demonstrate ...
Fabrizio Gozzi   +13 more
doaj   +1 more source

RESISTANCE OF FOUR DIFFERENT LOCAL HYBRID CHICKENS TO INFECTIOUS BURSAL DISEASE INFECTION

open access: yesThe Iraqi Journal of Veterinary Medicine, 2021
Four hundred, one day old chicks, of four hybrids, were divided into four groups, reared on the floor for ten weeks. The hybrids were vaccinated with live IBD vaccine at 14, 35, 56 days. Maternal antibody titers, antibody titer after each vaccination and
M. A. Al-Zuhairy
doaj   +1 more source

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