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The role of antibody indexes in clinical virology [PDF]
Serological techniques are an essential part of the diagnostic tools used in clinical virology. Among these techniques, antibody indexes are not novel, but do require specific expertise. Their niche has expanded substantially in recent years due to increasing evidence of their performance to diagnose viral infections.This narrative review describes the
Maarten J. Titulaer +2 more
exaly +5 more sources
Anti-John Cunningham virus antibody index levels in multiple sclerosis patients treated with rituximab, fingolimod, and dimethyl fumarate. [PDF]
Background: Progressive multifocal leukoencephalopathy (PML), a potentially fatal demyelinating disease caused by the John Cunningham virus (JCV), can occur as a complication of treatment with rituximab, fingolimod, and dimethyl fumarate.
Farley S +7 more
europepmc +2 more sources
Longitudinal analyses of anti-JCV antibody index for risk assessment of progressive multifocal leukoencephalopathy. [PDF]
Risk assessment for natalizumab-associated progressive multifocal leukoencephalopathy (Nat-PML) comprises the anti-JC virus (JCV) antibody index (AI). The anti-JCV AI was longitudinally determined in a natalizumab-treated MS cohort (Nat-MS, n = 468) and ...
Salmen A +8 more
europepmc +2 more sources
In natalizumab‐treated patients without previous immunosuppressive treatment, the JCV antibody index is used to stratify PML risk. A high index value indicates that the risk to develop PML is significantly elevated, although probably about 99% of ...
Tilman Schneider-Hohendorf +1 more
exaly +2 more sources
Antibody Index In Neuroimmunoepidemiological Studie
The evaluation of the neuroimmunoepidemiological response from the reibergram allows the determination of the specific antibody index for a determined etiological agent.
Eneida Barrios-Lamoth +1 more
doaj +1 more source
Abstract Objective—To investigate the use of a specific antibody index (AI) that relates Sarcocystis neurona–specific IgG quotient (QSN) to total IgG quotient (QIgG) for the detection of the anti–S neurona antibody fraction of CNS origin in CSF samples obtained from horses after intragastric administration of S neurona sporocysts.
K. Heskett, R. MacKay
semanticscholar +3 more sources
Despite tremendous efforts in the field of targeted cancer therapy with antibody–drug conjugates (ADCs), attrition rates have been high. Historically, the priority in ADC development has been the selection of target, antibody, and toxin, with little ...
Jorge M. M. Verkade +5 more
doaj +3 more sources
Laboratory diagnosis of Lyme neuroborreliosis (LNB) is challenging, and validated diagnostic algorithms are lacking. Therefore, this retrospective cross-sectional study aimed to compare the diagnostic performance of seven commercial antibody assays for ...
Tamara van Gorkom +7 more
doaj +1 more source
Background and Objectives: A cross-sectional single-center study was conducted to investigate the etiology in hypertensive anterior uveitis whose clinical features are not fully distinctive from cytomegalovirus or from rubella virus and to demonstrate ...
Fabrizio Gozzi +13 more
doaj +1 more source
RESISTANCE OF FOUR DIFFERENT LOCAL HYBRID CHICKENS TO INFECTIOUS BURSAL DISEASE INFECTION
Four hundred, one day old chicks, of four hybrids, were divided into four groups, reared on the floor for ten weeks. The hybrids were vaccinated with live IBD vaccine at 14, 35, 56 days. Maternal antibody titers, antibody titer after each vaccination and
M. A. Al-Zuhairy
doaj +1 more source

