Journal of Neuroinflammation, 2020 Background Progressive multifocal leukoencephalopathy (PML) caused by JC virus (JCV) is a rare but serious complication of some disease-modifying drugs used to treat multiple sclerosis (MS).
Mitsuru Watanabe +9 more
doaj +1 more source
Turkish Journal of Hematology, 2021 Objective: The aim of this study is to investigate post-COVID-19 antibody titers in patients who received convalescent plasma (CP) in addition to standard-of-care treatment.
Ahmet Omma +4 more
doaj +1 more source
Application of anti-HBc quantitative examination in clinical management of chronic hepatitis B virus infection [PDF]
Jichu yixue yu linchuang, 2022 The quantification of hepatitis B virus(HBV) core antibody (anti-HBc) is related to host immunity and can be detected in the serum of patients with current or past infections.
DU Xin-yi, MAO Xiao-rong, LI Jun-feng
doaj +1 more source
Surface Plasmon Resonance kinetic analysis of the interaction between G-quadruplex nucleic acids and an anti-G-quadruplex monoclonal antibody [PDF]
, 2018 Background G-quadruplexes (G4s) are nucleic acids secondary structures formed in guanine-rich sequences. Anti-G4 antibodies represent a tool for the direct investigation of G4s in cells.
Lago, Sara +3 more
core +1 more source
The Turkish Journal of Ear Nose and Throat, 2023 Objective: The potential predictive value of body mass index, stress management ability, and thiobarbituric acid reactive substances (TBARS) levels for antibody levels in Hashimoto’s thyroiditis (HT) were evaluated.Materials and Methods: Two hundred ...
Murat Giriş +6 more
doaj +1 more source
M2I-1 disrupts the in vivo interaction between CDC20 and MAD2 and increases the sensitivities of cancer cell lines to anti-mitotic drugs via MCL-1s [PDF]
, 2019 Background Drugs such as taxanes, epothilones, and vinca alkaloids are widely used in the treatment of breast, ovarian, and lung cancers but come with major side effects such as neuropathy and loss of neutrophils and as single agents have a lack of ...
Dang, Nanmao +7 more
core +1 more source
The Influence of Blood Contamination on Cerebrospinal Fluid Diagnostics
Frontiers in Neurology, 2019 Background: Blood contamination due to traumatic lumbar puncture presents a diagnostic pitfall in cerebrospinal fluid (CSF) analysis. It is controversially discussed if phagocytosis of erythrocytes which can be found in the CSF after subarachnoid ...
Philipp Schwenkenbecher +12 more
doaj +1 more source
Engineered anti-CD70 antibody-drug conjugate with increased therapeutic index [PDF]
Molecular Cancer Therapeutics, 2008 Abstract An anti-CD70 antibody conjugated to monomethylauristatin F (MMAF) via a valine-citrulline dipeptide containing linker has been shown previously to have potent antitumor activity in renal cell cancer xenograft studies. Here, we generated a panel of humanized anti-CD70 antibody IgG variants and conjugated them to MMAF to study ...
Charlotte F, McDonagh +13 more
openaire +2 more sources
Stratification and monitoring of natalizumab-associated progressive multifocal leukoencephalopathy risk: recommendations from an expert group [PDF]
, 2015 The use of natalizumab for highly active relapsing-remitting multiple sclerosis (MS) is influenced by the occurrence of progressive multifocal leukoencephalopathy (PML).
Craner, M +10 more
core +1 more source
Fibronectin rescues estrogen receptor α from lysosomal degradation in breast cancer cells [PDF]
, 2018 Estrogen receptor α (ERα) is expressed in tissues as diverse as brains and mammary glands. In breast cancer, ERα is a key regulator of tumor progression.
Acconcia +111 more
core +2 more sources