Results 31 to 40 of about 6,557,782 (278)

Body Mass Index Influence for the Personalization of the Monoclonal Antibodies Therapy for Psoriasis [PDF]

open access: yesLife, 2021
Psoriasis is a chronic inflammatory, autoimmune-mediated disease that affects millions of individuals worldwide. Advances in treatment with biological agents represented by monoclonal antibodies, such as TNF-α inhibitors (TNFI), IL-17A and IL-12/23 antagonists have not only benefited from outstanding clinical efficacy with lower side effects compared ...
Flavia Anghel   +2 more
openaire   +3 more sources

Chemical Site-Specific Conjugation Platform to Improve the Pharmacokinetics and Therapeutic Index of Antibody-Drug Conjugates.

open access: yesMolecular Pharmaceutics, 2021
To overcome a lack of selectivity during the chemical modification of native non-engineered antibodies, we have developed a technology platform termed "AJICAP" for the site-specific chemical conjugation of antibodies through the use of a class of IgG Fc ...
Yutaka Matsuda   +11 more
semanticscholar   +1 more source

EFFECT OF BROILER DIET COMPOSITION ON NEWCASTLE DISEASE ANTIBODY PRODUCTION [PDF]

open access: yesMesopotamia Journal of Agriculture, 2006
An experiment was conducted at the college of veterinary medicine to investigate the effect of two types of broiler starter diets, with or without animal protein, on Newcastle disease antibody production. Bursal weight index was also studied.
A. M. Saeed Al Saigh
doaj   +1 more source

Anti-nucleocapsid IgG antibodies in SARS-CoV-2 recovered health care workers: One year follow-up study

open access: yesInternational Journal of Immunopathology and Pharmacology, 2023
Objective: The objective of this study was to evaluate the magnitude and durability of the anti-nucleocapsid-IgG antibody titer in healthcare workers previously infected with SARS-CoV-2 for a period of 12 months.
Ashfaq Ahmad   +3 more
doaj   +1 more source

CSF/serum ratios: modern approach to assess intrathecal response

open access: yesИнфекция и иммунитет
CSF/serum ratios are the quotients of protein concentrations between the cerebrospinal fluid and blood serum. This method provides an objective assessment of proteins amount and origin in the cerebrospinal fluid.
Alexandra M. Deomkina   +3 more
doaj   +1 more source

Analysis of Immunological Memory for John Cunningham Virus in a Mexican Population of Patients with Multiple Sclerosis Under Treatment

open access: yesBiomedicines
Background/Objectives: Multiple sclerosis (MS) is a disease characterized by demyelination and axonal damage of the central nervous system. Despite the observed benefits, highly effective treatment (HET)-based therapy has adverse effects, which include ...
Silvia García   +9 more
doaj   +1 more source

Peroxidase antibody test for mucocutaneous leishmaniasis serology performance indexes and comparison with a fluorescent antibody test: Comparação com o desempenho da reação de imunofluorescência

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1988
Performance indexes of the peroxidase antibody test were compared to that of the fluorescent antibody test. The peroxidase antibody test had a statistically higher sensitivity and negative predictive value and a higher efficiency than the fluorescent ...
Beatriz J. Celeste   +2 more
doaj   +1 more source

Improving national surveillance of Lyme neuroborreliosis in Denmark through electronic reporting of specific antibody index testing from 2010 to 2012.

open access: yesEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2015
Our aim was to evaluate the results of automated surveillance of Lyme neuroborreliosis (LNB) in Denmark using the national microbiology database (MiBa), and to describe the epidemiology of laboratory-confirmed LNB at a national level.
R. Dessau   +4 more
semanticscholar   +1 more source

Associations Between Symptoms, Donor Characteristics and IgG Antibody Response in 2082 COVID-19 Convalescent Plasma Donors

open access: yesFrontiers in Immunology, 2022
Many studies already reported on the association between patient characteristics on the severity of COVID-19 disease outcome, but the relation with SARS-CoV-2 antibody levels is less clear. To investigate this in more detail, we performed a retrospective
Marieke Vinkenoog   +18 more
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin   +17 more
wiley   +1 more source

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