Results 41 to 50 of about 447,696 (288)

The role of age in ocular toxoplasmosis: clinical signs of immunosenescence and inflammaging

Frontiers in Medicine
PurposeThis study aimed to investigate the association between age, immune response, and clinical presentation of ocular toxoplasmosis (OT).DesignThis was a monocentric, retrospective, observational cohort study.MethodsA review of the medical records of ...
Armin Taghavi Eraghi, Justus G. Garweg, Justus G. Garweg, Justus G. Garweg, Uwe Pleyer, Uwe Pleyer   +5 more
doaj   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

The effect of immunization schedule with the malaria vaccine candidate RTS,S/AS01E on protective efficacy and anti-circumsporozoite protein antibody avidity in African infants [PDF]

, 2015
The malaria vaccine RTS,S induces antibodies against the Plasmodium falciparum circumsporozoite protein (CSP) and the concentration of Immunoglobulin G (IgG) against the repeat region of CSP following vaccination is associated with protection from P ...
Mpina, Maxmilliam, Ajua, Anthony, Abdulla, Salim, Jongert, Erik, Cambron, Pierre, Ockenhouse, Chris F., Agnandji, Selidji Todagbe, Asante, Kwaku Poku, Owusu-Agyei, Seth, Mwangoka, Grace, Kremsner, Peter G., Lell, Bertrand, Mordmüller, Benjamin, Salim, Nahya, Lievens, Marc, Ockenhouse, Chris F, Kremsner, Peter G, Vekemans, Johan, Tanner, Marcel   +18 more
core   +1 more source

Vaccination of SARS-CoV-2-infected individuals expands a broad range of clonally diverse affinity-matured B cell lineages

Nature Communications, 2023
Vaccination of SARS-CoV-2 convalescent individuals generates broad and potent antibody responses. Here, we isolate 459 spike-specific monoclonal antibodies (mAbs) from two individuals who were infected with the index variant of SARS-CoV-2 and later ...
Mark Chernyshev, Mrunal Sakharkar, Ruth I. Connor, Haley L. Dugan, Daniel J. Sheward, C. G. Rappazzo, Aron Stålmarck, Mattias N. E. Forsell, Peter F. Wright, Martin Corcoran, Ben Murrell, Laura M. Walker, Gunilla B. Karlsson Hedestam   +12 more
doaj   +1 more source

Antibody-coating of bacteria in the urine in relation to various immunologic indexes

Kidney International, 1981
Little is known about the immunologic aspects of antibody coating, though the test for determining antibody-coated bacteria in urine has been examined for its diagnostic uses by many authors after its inauguration in 1974. In adults with chronic pyelonephritis with and without antibody-coated bacteria in the urine, we tested whether bacterial coating ...
Budde, Eckhard, Naumann, Günter, Nimmich, Wolfgang, Handschuck, Irmhild, Hudemann, Bernd   +4 more
openaire   +2 more sources

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Synovial antibody index as a marker of synovitis in knee osteoarthritis

Journal of Medicine and Palliative Care, 2022
As this is an editorial letter, no abstract avialable.
openaire   +2 more sources

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

-Neurofilament Antibody Index

, 2001
Antibody responses to Acinetobacter (five strains), Pseudomonas aeruginosa, Escherichia coli, myelin basic protein (MBP), and neurofilaments were measured in sera from 26 multiple sclerosis (MS) patients, 20 patients with cerebrovascular accidents (CVA),
J. Croker, J. Vowles, Croker, J, A. Ebringer, L. E. Hughes, Chamoun, V, Bonell, S, P. Cunningham, V. Chamoun, Vowles, J, Natt, R S, Thompson, E J, S. Bonell, Tiwana, H, E. J. Thompson, Hughes, L E, R. S. Natt, Ebringer, A, C. Wilson, Cunningham, P, Wilson, C, H. Tiwana   +21 more
core   +1 more source

Engineered anti-CD70 antibody-drug conjugate with increased therapeutic index [PDF]

Molecular Cancer Therapeutics, 2008
Abstract An anti-CD70 antibody conjugated to monomethylauristatin F (MMAF) via a valine-citrulline dipeptide containing linker has been shown previously to have potent antitumor activity in renal cell cancer xenograft studies. Here, we generated a panel of humanized anti-CD70 antibody IgG variants and conjugated them to MMAF to study ...
Charlotte F, McDonagh, Kristine M, Kim, Eileen, Turcott, Lindsay L, Brown, Lori, Westendorf, Tiffany, Feist, Django, Sussman, Ivan, Stone, Martha, Anderson, Jamie, Miyamoto, Robert, Lyon, Stephen C, Alley, Hans-Peter, Gerber, Paul J, Carter   +13 more
openaire   +2 more sources