Results 181 to 190 of about 89,614 (291)

Demographic and genetic factors shape the epitope specificity of the human antibody repertoire against viruses. [PDF]

Nat Immunol
Olin A, Pou C, Jaquaniello A, Crook J, Tan Z, Roux M, Dubois F, Charbit B, Liu D, Donnadieu F, Garcia L, Lambert C, Bloch E, Clave E, Araujo IL, Toubert A, Rotival M, Simon-Lorière E, White M, Brodin P, Duffy D, Quintana-Murci L, Patin E, Milieu Intérieur Consortium.   +23 more
europepmc   +1 more source

Next-Generation Serology by Mass Spectrometry: Readout of the SARS-CoV-2 Antibody Repertoire. [PDF]

J Proteome Res, 2022
Melani RD, Des Soye BJ, Kafader JO, Forte E, Hollas M, Blagojevic V, Negrão F, McGee JP, Drown B, Lloyd-Jones C, Seckler HS, Camarillo JM, Compton PD, LeDuc RD, Early B, Fellers RT, Cho BK, Mattamana BB, Goo YA, Thomas PM, Ash MK, Bhimalli PP, Al-Harthi L, Sha BE, Schneider JR, Kelleher NL.   +25 more
europepmc   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Delineating inter- and intra-antibody repertoire evolution with AntibodyForests. [PDF]

Bioinformatics
van Ginneken D, Tromp V, Stalder L, Cotet TS, Bakker S, Samant A, Reddy ST, Yermanos A.   +7 more
europepmc   +1 more source

Machine Learning Detects Anti-DENV Signatures in Antibody Repertoire Sequences. [PDF]

Front Artif Intell, 2021
Horst A, Smakaj E, Natali EN, Tosoni D, Babrak LM, Meier P, Miho E.   +6 more
europepmc   +1 more source

A Tripartite Model for EBV‐Driven Multiple Sclerosis: B Cell Survival, Altered Self‐Presentation, and HLA‐DR15‐Restricted T Cell Cross‐Reactivity

iNew Medicine, EarlyView.
ABSTRACT This commentary integrates findings from three recent Cell reports to establish a unified mechanistic model of multiple sclerosis (MS) driven by the interplay between Epstein‐Barr virus (EBV) and the HLA‐DR15 genotype. EBV promotes CNS autoimmunity through three distinct but intersecting mechanisms.
Fang Zhu, Arnaud John Kombe Kombe, Tengchuan Jin   +2 more
wiley   +1 more source

Impact of Maternal Diabetes in Pregnancy on Newborn IgG Antibody Repertoire and Infection Risk in the First 6 Months of Life. [PDF]

Diabetes Care
Wang G, Ruczinski I, Larman HB, Gutierrez MJ, Frischmeyer-Guerrerio PA, Hong X, Ji H, Pearson C, Adams WG, Wang X.   +9 more
europepmc   +1 more source

Enhancer-instructed epigenetic landscape and chromatin compartmentalization dictate a primary antibody repertoire protective against specific bacterial pathogens. [PDF]

Nat Immunol, 2023
Barajas-Mora EM, Lee L, Lu H, Valderrama JA, Bjanes E, Nizet V, Feeney AJ, Hu M, Murre C.   +8 more
europepmc   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

Genomic Profiling of Antibody Repertoire in Rongchang Pigs Uncovers Conserved V(D)J Gene Usage and Breed-Specific Diversification. [PDF]

Genes (Basel)
Li Q, Wu M, Liu X, Wu X, Ding C, Ge L, Zhang H, Sun J.   +7 more
europepmc   +1 more source