Results 91 to 100 of about 552,206 (313)
Cytotoxicity of four anticancer drugs on human (HBL) and mouse (Bl6) melanoma cells in vitro
: Anticancer Researchinfo:eu-repo/semantics ...
Dubois, Jacques +6 more
core
An introduction to anticancer drugs [PDF]
An introduction to anticancer drugs\ud 24.1 Introduction\ud 24.2 The rationale behind anticancer drug therapy\ud 24.3 Drugs used in cancer\ud 24.3.1 Alkylating agents\ud 24.3.2 Cytotoxic antibiotics\ud 24.3.3 Antimetabolites\ud 24.3.4 Microtubule ...
Mullaney, Ian
core
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Pancreatic arteriovenous malformation (pAVM) is a very rare entity, as less than 100 cases are reported in the international literature. Patients with pAVM may be asymptomatic or may present a wide range of symptoms, such as vague pain, feeling of ...
Olga Nikolaidou, MD +4 more
doaj +1 more source
Highly Potent Rhenium(I) Tricarbonyl Complexes with Dual Anticancer and Anti-Angiogenic Activity Against Colorectal Carcinoma [PDF]
Synthesized and characterized a series of rhenium(I) trycarbonyl-based complexes with increased lipophilicity. Two of these novel compounds were discovered to possess remarkable anticancer, anti-angiogenic and antimetastatic activity in vivo (zebrafish ...
Joachim, Delasoie +6 more
core +1 more source
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Understanding and Improving Platinum Anticancer Drugs - Phenanthriplatin [PDF]
Approximately half of all patients who receive anticancer chemotherapy are treated with a platinum drug. Despite the widespread use of these drugs, the only cure that can be claimed is that of testicular cancer following cisplatin treatment. This article
Lippard, Stephen J +6 more
core
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Cardiotoxicity of Anticancer Therapies
Cardiovascular diseases and cancer continue to remain major causes of mortality and morbidity. However, overall cancer death rates have declined 20% from their peak in 1991. These declines reflect changing patterns in smoking, prevention, earlier diagnosis, and better treatment options in chemotherapy.
Raghunandan, Muppidi +5 more
openaire +2 more sources
Organometallic iridium(III) cyclopentadienyl anticancer complexes containing C,N-chelating ligands [PDF]
Organometallic IrIII cyclopentadienyl complexes [(η5-Cpx)Ir(CN)Cl] {Cpx = Cp*, CN = 2-(p-tolyl)pyridine (1), 2-phenylquinoline (2), 2-(2,4-difluorophenyl)pyridine (3), Cpx = tetramethyl(phenyl)cyclopentadienyl (Cpxph), CN = 2-phenylpyridine (4), and Cpx =
Liu, Zhe +9 more
core +1 more source

