Results 151 to 160 of about 417,719 (249)

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

Ferrocenyl ferroptosis inducers as an emerging class of anticancer agents: a mini review. [PDF]

RSC Med Chem
Klarek M, Gautam A, Kowalski K.
europepmc   +1 more source

The Anticancer Effect of Phytochemicals and Potential of Breynia cernua: An overview

, 2022
Muhammad Hilman Azzam, Nisa Fauziah, Hesti Lina Wiraswati   +2 more
openalex   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source

Discovery of Pyrazoline Benzenesulfonamide Derivatives as Anticancer Agents: A Review. [PDF]

Drug Des Devel Ther
Hasyim DM, Musfiroh I, Hendra R, Kamarulzaman EE, Ritmaleni R, Muchtaridi M.   +5 more
europepmc   +1 more source

A New Era in Anticancer Therapy/Imatinib—A New Era in Anticancer Therapy [PDF]

, 2008
N Danchev, Irina Nikolova, Georgi Momekov   +2 more
openalex   +1 more source

Nanocarrier based precise approaches for anticancer agents in treatment of breast cancer.

, 2021
Ujjwala Kandekar, Rohini Pujari
openalex   +2 more sources

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source

Correction: A novel peptide derived from Zingiber cassumunar rhizomes exhibits anticancer activity against the colon adenocarcinoma cells (Caco-2) via the induction of intrinsic apoptosis signaling. [PDF]

PLoS One
Promsut K, Sangtanoo P, Srimongkol P, Saisavoey T, Puthong S, Buakeaw A, Reamtong O, Nutho B, Karnchanatat A.   +8 more
europepmc   +1 more source

Anticancer activity and DNA interaction of bis(pyridyl)allene-derived metal complexes

, 2023
Hanna K. Maliszewska, Mahmoud A. S. Abdelhamid, María J. Marín, Zoë A. E. Waller, María Paz Muñoz   +4 more
openalex   +1 more source