Results 61 to 70 of about 10,530,811 (405)

Investigation on Quantitative Structure-Activity Relationships of 1,3,4 Oxadiazole Derivatives as Potential Telomerase Inhibitors [PDF]

, 2018
The published manuscript is available at EurekaSelect via http://www.eurekaselect.com/164022/article, DOI : 10.2174/1570163815666180724113208. © 2018 Bentham ScienceA series of 1,3,4-oxadiazole derivatives with significant broad-spectrum anticancer ...
Almerico, Anna Maria, Pecoraro, Beatrice, Tutone, Marco   +2 more
core   +2 more sources

Anticancer Activity of 4-Aryl-1,4-Dihydropyridines

Future Pharmacology
We have synthesized 22 symmetric and asymmetric 4-aryl-1,4-dihydropyridines (1,4-DHPs) by a “green” microwave-assisted one-pot multicomponent Hantzsch reaction and evaluated their cytotoxicity to three human cancer cell lines regarding U-251MG (human ...
Thaís A. S. Oliveira, Jackson B. A. Silva, Tábata R. Esperandim, Nathália O. Acésio, Denise C. Tavares, Antônio E. M. Crotti   +5 more
doaj   +1 more source

Synthesis and anticancer activity of (+)-nopinone-based 2-amino-3-cyanopyridines [PDF]

Frontiers of Agricultural Science and Engineering, 2015
Twelve (+)-nopinone-based 2-amino-3-cyanopyridines 4a—l were synthesized from (—)-β-pinene. The structures of these compounds were characterized by FT-IR, 1H NMR, and ESI-MS.
Shengliang LIAO,Shibin SHANG,Minggui SHEN,Xiaoping RAO,Hongyan SI,Jie SONG,Zhanqian SONG
doaj   +1 more source

Anticancer of genus Syzygium: a systematic review

Exploration of Targeted Anti-tumor Therapy, 2023
Aim: One in eight fatalities globally are considered cancer-related. The need for cancer therapy is growing. Natural products continue to play a role in drug development, as up to 50% of authorized drugs in the last 30 years have been isolated from ...
Mahmoud Dogara Abdulrahman, Harmand A. Hama   +1 more
doaj   +1 more source

Expression proteomics reveals protein targets and highlights mechanisms of action of small molecule drugs

, 2014
Phenomenological screening of small molecule libraries for anticancer activity yields potentially interesting candidate molecules, with a bottleneck in the determination of drug targets and the mechanism of anticancer action.
Chernobrovkin, Alexey, Vicente, Consuelo Marin, Visa, Neus, Zubarev, Roman A.   +3 more
core   +1 more source

QSAR studies on Withanolide analogs for anticancer activity [PDF]

, 2011
Withanolides are a group of pharmacologically active compounds present in most prodigal amounts in roots and leaves of Withania somnifera (Indian ginseng), one of the most important medicinal plants of Indian systems of medicine.
Dharmendra Kumar Yadav, Feroz Khan, Rajender S. Sangwan   +2 more
core   +2 more sources

Antioxidant, antimicrobial and anticancer activity of the lichens Cladonia furcata, Lecanora atra and Lecanora muralis

BMC Complementary and Alternative Medicine, 2011
Background The aim of this study is to investigate in vitro antioxidant, antimicrobial and anticancer activity of the acetone extracts of the lichens Cladonia furcata, Lecanora atra and Lecanora muralis. Methods Antioxidant activity was evaluated by five
Stanojković Tatjana P, Kosanić Marijana M, Ranković Branislav R   +2 more
doaj   +1 more source

28-O-Acetyl-3-O’-(Phenylpropynoyl)Betulin

Molbank, 2023
New derivative of 28-acetylbetulin containing a phenylpropynoyl moiety at the C-3 position was obtained by Steglich method. The chemical structure of this compound has been determined through 1H NMR, 13C NMR, IR, EI MS and HRMS.
Ewa Bębenek, Monika Kadela-Tomanek, Beata Filip-Psurska, Elwira Chrobak   +3 more
doaj   +1 more source

The impact of menopause on bone, zoledronic acid, and implications for breast cancer growth and metastasis [PDF]

, 2012
Recent data from the AZURE, ABCSG-12, and ZO-FAST clinical trials have challenged our understanding of the potential anticancer activity of zoledronic acid (ZOL). Although the results of these studies may appear to be conflicting on the surface, a deeper
Arrington, Avcu, Baum, Bilezikjian, Binkley, Bismar, Black, Bourdeau, Brown, Bundred, Burger, Burger, Centrella, Chapman, Cheleuitte, Chiu, Clowes, Coleman, Coscia, Coxon, Croucher, de Boer, Del Mastro, Dixon, Duivenvoorden, Edlund, Edlund, Esparza-Lopez, Folkerd, Gasser, Gasser, Geisler, Giraudo, Gnant, Gnant, Gnant, Gnant, Gordon, Guo, Hackshaw, Hamilton, Hampl, Hershman, Hershman, Hines, Hiraga, Hofbauer, Hornby, Ibrahim, Jimenez-Gordo, Juarez, Kaplan, Kaplan, Kardassis, Khosla, Kirkbride, Labrinidis, Le Goff, Lee, Lewis, Lindberg, Little, Little, Meads, Melani, Monkkonen, Muller, Nicks, Ogata, Ottewell, Ottewell, Ottewell, Pataki, Perrien, Perrien, Peyruchaud, Pfeilschifter, Podworny, Rachner, Rannevik, Roelofs, Rogers, Rosen, Rosen, Saika, Sasser, Sasser, Shiozawa, Shipman, Sims, Sirola, Skerjanec, Sowers, Studebaker, Sun, Tang, Thompson, Thurlimann, Uncu, van de Velde, Weiss, Wels, Welt, Wiater, Winter   +104 more
core   +1 more source

PEGylated nano-graphene oxide as a nanocarrier for delivering mixed anticancer drugs to improve anticancer activity

Scientific Reports, 2020
Due to their high specific surface area, graphene oxide and graphene oxide-base nanoparticles have great potential both in dual-drug delivery and combination chemotherapy.
X. Pei, Zhou Zhu, Zhoujie Gan, Junyu Chen, Xin Zhang, Xinting Cheng, Q. Wan, Jian Wang   +7 more
semanticscholar   +1 more source