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Potential Anticancer Activity of Auranofin
Chemical and Pharmaceutical Bulletin, 2019 Gold compounds have a long history of use in medicine. Auranofin was developed more than 30 years ago as an oral therapy for rheumatoid arthritis. Now, however, auranofin is rarely used in clinical practice despite its efficacy for treating rheumatoid arthritis because more novel antirheumatic medications are available.
Isao, Momose +2 more
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Anticancer Activity of the Antibiotic Clioquinol [PDF]
Cancer Research, 2005 AbstractClioquinol, a metal chelator, has been used for many years as an antimicrobial agent and more recently as a potential treatment for Alzheimer's disease. Because it binds copper and zinc, metals essential for the activity of the enzyme superoxide dismutase-1 (SOD1), a potential target for anticancer drug development, we investigated its effects ...
Wei-Qun, Ding +4 more
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Molecules, 2020 The link between the antimicrobial and anticancer activity of peptides has long been studied, and the number of peptides identified with both activities has recently increased considerably. In this work, we hypothesized that designed peptides with a wide
Davor Juretić +6 more
doaj +1 more source
Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD(H)-dependent and (ii) p53 independent pathways [PDF]
, 2014 Most cancer cells use aerobic glycolysis to fuel their growth. The enzyme lactate dehydrogenase-A (LDH-A) is key to cancer’s glycolytic phenotype, catalysing the regeneration of nicotinamide adenine dinucleotide (NAD þ ) from reduced nicotinamide adenine
Allison, Simon J. +6 more
core +1 more source
Anticancer Activity of Cynomorium coccineum [PDF]
Cancers, 2018 The extensive applications of Cynomorium species and their rich bioactive secondary metabolites have inspired many pharmacological investigations. Previous research has been conducted to examine the biological activities and numerous interesting pharmaceutical activities have been reported. However, the antitumor activities of these species are unclear.
Mouna Sdiri +6 more
openaire +3 more sources
Developing Strategy for a Successful Antioxidant, Anticancer Activity via an Improved Method Prepared to Porous Silicon Nanoparticles [PDF]
Journal of Applied Sciences and Nanotechnology, 2021 Porous silicon nanoparticles, or PSNPs, are one of the most common NPS with distinct characteristics. PSNPs were created using an enhanced approach known as the electrochemical etching process.
Kareem Jawad, Butheina Hasson
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Anticancer efficacy of phenolics based structurally related compounds and their radical scavenging action [PDF]
, 2011 Cancer, one of the leading causes of death worldwide, is an abnormal cell proliferation that fails to respond to the normal signals. In an effort to eradicate the growing menace of cancer, a clear understanding of fundamental biology and molecular ...
Arvind S. Negi +3 more
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Anticancer Activity of Papaver Somniferum
Journal of the Turkish Chemical Society, Section A: Chemistry, 2016 This work describes the pharmacological activity of extracts of Papaver somniferum, a poppy species. P. somniferum products are still considered as a unique source of drug for many diseases.
Döne Aslı Güler +3 more
doaj +1 more source
Understanding the Therapeutic Potential of Ascorbic Acid in the Battle to Overcome Cancer
Biomolecules, 2021 Cancer, a fatal disease, is also one of the main causes of death worldwide. Despite various developments to prevent and treat cancer, the side effects of anticancer drugs remain a major concern.
Jurnal Reang +3 more
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Inhibiting RRM2 to enhance the anticancer activity of chemotherapy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020 RRM2, the small subunit of ribonucleotide reductase, is identified as a tumor promotor and therapeutic target. It is common to see the overexpression of RRM2 in chemo-resistant cancer cells and patients.
Yaqiong Zhan +10 more
semanticscholar +1 more source