Results 41 to 50 of about 6,504,034 (299)

A study on antimicrobial and anticancer properties of Cissus quadrangulris using lung cancer cell line

open access: yesCancer Treatment and Research Communications, 2023
Cissus quadrangularis plant from Vitaceae family, native in India. Many parts of this plant have medicinal values but most precious is stem of this plant.
Sholapuri Payani   +3 more
doaj   +1 more source

Anticancer Activity of the Antibiotic Clioquinol [PDF]

open access: yesCancer Research, 2005
Abstract Clioquinol, a metal chelator, has been used for many years as an antimicrobial agent and more recently as a potential treatment for Alzheimer's disease. Because it binds copper and zinc, metals essential for the activity of the enzyme superoxide dismutase-1 (SOD1), a potential target for anticancer drug development, we ...
Wei-Qun, Ding   +4 more
openaire   +2 more sources

Metal complexes as DNA intercalators [PDF]

open access: yes, 2011
DNA has a strong affinity for many heterocyclic aromatic dyes, such as acridine and its derivatives. Lerman in 1961 first proposed intercalation as the source of this affinity, and this mode of DNA binding has since attracted considerable research ...
Peter J. Sadler   +3 more
core   +1 more source

Anticancer Activity of Cynomorium coccineum [PDF]

open access: yesCancers, 2018
The extensive applications of Cynomorium species and their rich bioactive secondary metabolites have inspired many pharmacological investigations. Previous research has been conducted to examine the biological activities and numerous interesting pharmaceutical activities have been reported. However, the antitumor activities of these species are unclear.
Mouna Sdiri   +6 more
openaire   +3 more sources

Functionalization of osmium arene anticancer complexes with (poly)arginine : effect on cellular uptake, internalization, and cytotoxicity [PDF]

open access: yes, 2011
Attaching peptides to metallodrugs may result in improved biological properties of the complexes. The potential use of cell penetrating peptides (CPPs) as cell delivery vectors is attractive, since directed cell uptake of (metallo)drugs remains a major ...
Rijt, Sabine H. van   +7 more
core   +1 more source

Novel Papaverine Metal Complexes with Potential Anticancer Activities

open access: yesMolecules, 2020
Cancer is one of the leading causes of death worldwide. Although several potential therapeutic agents have been developed to efficiently treat cancer, some side effects can occur simultaneously.
Ahmed Gaber   +4 more
doaj   +1 more source

In vitro study of pinostrobin propionate and pinostrobin butyrate: Cytotoxic activity against breast cancer cell T47D and its selectivity index

open access: yesJournal of Public Health in Africa, 2023
Backgrounds: Pinostrobin has the potential activity as an anti-cancer. However, its activity is still lower than the anticancer drugs on the market. To increase its activity, pinostrobin derivatives have been synthesized, namely pinostrobin propionate ...
Tri Widiandani   +6 more
doaj   +1 more source

Bioassays for Anticancer Activities

open access: yes, 2013
The MTT/MTS in vitro cell proliferation assay is one of the most widely used assays for evaluating preliminary anticancer activity of both synthetic derivatives and natural products and natural product extracts. The highly reliable, colorimetric based assay is readily performed on a wide range of cell lines. This assay gives an indication of whole cell
McCauley, Janice   +2 more
openaire   +3 more sources

Antimicrobial activity, antiproliferative activity, amylase inhibitory activity and phytochemical analysis of ethanol extract of corn (Zea mays L.) silk

open access: yesCurrent Research in Green and Sustainable Chemistry, 2021
In this study, ethanolic extract of Zea mays L was utilized against urinary tract infection (UTI) causing bacteria, vegetable spoilage causing fungi and anticancer activity.
S. Abirami   +7 more
doaj   +1 more source

Natural and Synthetic Furanones with Anticancer Activity [PDF]

open access: yesNatural Product Communications, 2016
This paper describes the enantioselective synthesis of analogues of sapinofuranones A and B, namely 5-substitutes dihydro- and 5 H-furan-ones, and their in vitro growth inhibitory activity against six cancer cell lines in comparison with fungal furanones such as diplofuranone A, diplobifuranylones A and B, as well as ( S,S ...
CIMMINO, ALESSIO   +9 more
openaire   +6 more sources

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