Results 31 to 40 of about 11,879,963 (351)

Anticancer activity of oxovanadium compounds [PDF]

Biomeditsinskaya Khimiya, 2012
Cytotoxic and antitumor activity of the biligand vanadyl derivative of L-malic acid (bis(L-malato)oxovanadium(IV) (VO(mal) ) was investigated in comparison with inorganic vanadium(IV) compound - vanadyl sulfate (VOSO ) and also with oxovanadium monocomplex with L-malic acid (VO(mal)) and vanadyl biscomplex with acetylacetonate.
O Iu, Abakumova, O V, Podobed, N F, Beliaeva, A I, Tochilkin   +3 more
openaire   +2 more sources

QSAR studies on Withanolide analogs for anticancer activity [PDF]

, 2011
Withanolides are a group of pharmacologically active compounds present in most prodigal amounts in roots and leaves of Withania somnifera (Indian ginseng), one of the most important medicinal plants of Indian systems of medicine.
Dharmendra Kumar Yadav, Feroz Khan, Rajender S. Sangwan   +2 more
core   +2 more sources

Study of the Anticancer Potential of Plant Extracts Using Liver Tumor Microphysiological System

Life, 2022
Background: Plants have been considered a vital source of modern pharmaceutics since the paleolithic age. Contemporary chemotherapeutic drugs for cancer therapy are chemical entities sourced from plants. However, synthetic drugs or their derivatives come
Hafiz Muhammad Umer Farooqi, Anupamma Sammantasinghar, Farzana Kausar, Muhammad Awais Farooqi, Abdul Rahim Chethikkattuveli Salih, Kinam Hyun, Jong-Hwan Lim, Atif Ali Khan Khalil, Abdul Samad Mumtaz, Kyung Hyun Choi   +9 more
doaj   +1 more source

New trends for metal complexes with anticancer activity [PDF]

, 2008
Medicinal inorganic chemistry can exploit the unique properties of metal ions for the design of new drugs. This has, for instance, led to the clinical application of chemotherapeutic agents for cancer treatment, such as cisplatin. The use of cisplatin is,
Ang, Ang, Barnard, Barnes, Bednarski, Bergamo, Bregman, Calderone, Casini, Debreczeni, Dixon, Dyson, Failes, Feazell, Guo, Habtemariam, Hall, Hambley, Hannon, Harris, Heringova, Hillard, Hotze, James, Jung, Komeda, Liu, Lutterman, MacDiarmid, Mackay, Mackay, McNae, Meggers, Milacic, Noor, Oleksi, Orvig, Ott, Pascu, Peacock, Peter J Sadler, Pieter CA Bruijnincx, Reed, Schatzschneider, Schlawe, Scolaro, Smalley, Sun, Thompson, Timerbaev, Urig, Urig, van Zutphen, Wang, Weidt, Yan, Yang   +56 more
core   +1 more source

Isocorydine Derivatives and Their Anticancer Activities [PDF]

Molecules, 2014
In order to improve the anticancer activity of isocorydine (ICD), ten isocorydine derivatives were prepared through chemical structure modifications, and their in vitro and in vivo activities were experimentally investigated. 8-Amino-isocorydine (8) and 6a,7-dihydrogen-isocorydione (10) could inhibit the growth of human lung (A549), gastric (SGC7901 ...
Mei Zhong, Yanjuan Liu, Junxi Liu, Duolong Di, Mengrou Xu, Yaya Yang, Wenguang Li, Yali Chen, Jinxia Liu   +8 more
openaire   +3 more sources

Anticancer activity of polyoxomolybdate

Biomedicine & Pharmacotherapy, 2006
Anticancer polyoxomolybdates have been investigated for medical application of polyoxometalates as discrete cluster anions of metal oxides. [NH3Pri]6[Mo7O24].3H2O (PM-8) has been recognized as one of significant antitumoral polyoxomolybdates. PM-8 had shown the growth suppression against several tumors, for examples, Co-4, human colon cancer, MX-1 ...
H, Yanagie, A, Ogata, S, Mitsui, T, Hisa, T, Yamase, M, Eriguchi   +5 more
openaire   +2 more sources

Gold amides as anticancer drugs: synthesis and activity studies [PDF]

, 2013
Modular gold amide chemotherapeutics: Access to modern chemotherapeutics with robust and flexible synthetic routes that are amenable to extensive customisation is a key requirement in drug synthesis and discovery.
Amagai, Amruta Shrikhande, Bjornstedt, Chen, Chris Gallop, Cox, Davis, Eddy M. E. Viseux, Eva Hoffmann, Fricker, Gabbiani, Helen Yong, Hickey, Hill, Lemke, Lima, Mariusz Bobin, Mark Roe, Mezailles, Modica-Napolitano, Omata, Orvig, Ott, Patra, Poole, Rebecca Gates, Shuvashri Chaudhuri, Sonya Newcombe, Stallings-Mann, Thaqi, Wetzel, Yan, Yannick Pace, Zhang, Zhang   +34 more
core   +1 more source

Synthesis and Biological Evaluation of Novel Aminochalcones as Potential Anticancer and Antimicrobial Agents

Molecules, 2019
A series of 18 aminochalcone derivatives were obtained in yields of 21.5−88.6% by applying the classical Claisen-Schmidt reaction. Compounds 4−9, 14 and 16−18 with 4-ethyl, 4-carboxy-, 4-benzyloxy- and 4-benzyloxy-3-methoxy groups were ...
Joanna Kozłowska, Bartłomiej Potaniec, Dagmara Baczyńska, Barbara Żarowska, Mirosław Anioł   +4 more
doaj   +1 more source

ANTIOXIDANT AND ANTICANCER ACTIVITIES OF MURBEI (Morus alba L.) STEM EXTRACT ON IN VITRO WiDr CANCER CELLS

Jurnal Farmasi Sains dan Komunitas, 2020
Mulberry (Morus alba L.) is considered as an important plant in traditional Chinese medicine, due to its various compounds, including phenols and flavanoids, which have antioxidant properties so that it can be a potential anticancer candidate. This study
Asril Burhan, Akbar Awaluddin, Zulham Zulham, Burhanuddin Taebe, Abdul Gafur   +4 more
doaj   +1 more source

Biochemical and mitochondrial membrane potential changes relating to betulinic acid-mediated anticancer activity in murine ascites Dalton's lymphoma

Phytomedicine Plus, 2022
Background: Betulinic acid, a naturally occurring pentacyclic triterpenoid is found in a variety of plants. A range of biological properties including anticancer activity has been reported for betulinic acid.
Anamika Bhaumik, Atanu Bhattacharjee, Surya Bali Prasad   +2 more
doaj   +1 more source