Results 31 to 40 of about 5,890,540 (213)

Metal complexes as DNA intercalators [PDF]

, 2011
DNA has a strong affinity for many heterocyclic aromatic dyes, such as acridine and its derivatives. Lerman in 1961 first proposed intercalation as the source of this affinity, and this mode of DNA binding has since attracted considerable research ...
Peter J. Sadler, Hong-Ke Liu, Sadler, P. J., Liu, Hong-Ke   +3 more
core   +1 more source

Understanding the Therapeutic Potential of Ascorbic Acid in the Battle to Overcome Cancer

Biomolecules, 2021
Cancer, a fatal disease, is also one of the main causes of death worldwide. Despite various developments to prevent and treat cancer, the side effects of anticancer drugs remain a major concern.
Jurnal Reang, Prabodh Chander Sharma, Vijay Kumar Thakur, Jaseela Majeed   +3 more
doaj   +1 more source

Investigation of the key chemical structures involved in the anticancer activity of disulfiram in A549 non-small cell lung cancer cell line

BMC Cancer, 2018
Background Disulfiram (DS), an antialcoholism medicine, demonstrated strong anticancer activity in the laboratory but did not show promising results in clinical trials. The anticancer activity of DS is copper dependent.
Kate Butcher, Vinodh Kannappan, Rajagopal Sharada Kilari, Mark R. Morris, Christopher McConville, Angel L. Armesilla, Weiguang Wang   +6 more
doaj   +1 more source

A study on antimicrobial and anticancer properties of Cissus quadrangulris using lung cancer cell line

Cancer Treatment and Research Communications, 2023
Cissus quadrangularis plant from Vitaceae family, native in India. Many parts of this plant have medicinal values but most precious is stem of this plant.
Sholapuri Payani, Matcha Bhaskar, Gandham Sandeep Kumar, Jangampalli Adi Pradeepkiran   +3 more
doaj   +1 more source

Novel Papaverine Metal Complexes with Potential Anticancer Activities

Molecules, 2020
Cancer is one of the leading causes of death worldwide. Although several potential therapeutic agents have been developed to efficiently treat cancer, some side effects can occur simultaneously.
Ahmed Gaber, Walaa F. Alsanie, Deo Nandan Kumar, Moamen S. Refat, Essa M. Saied   +4 more
doaj   +1 more source

In vitro study of pinostrobin propionate and pinostrobin butyrate: Cytotoxic activity against breast cancer cell T47D and its selectivity index

Journal of Public Health in Africa, 2023
Backgrounds: Pinostrobin has the potential activity as an anti-cancer. However, its activity is still lower than the anticancer drugs on the market. To increase its activity, pinostrobin derivatives have been synthesized, namely pinostrobin propionate ...
Tri Widiandani, Tiffany Tandian, Bagus D. Zufar, Andi Suryadi, Bambang T. Purwanto, Suko Hardjono, Siswandono Siswandono   +6 more
doaj   +1 more source

Antimicrobial activity, antiproliferative activity, amylase inhibitory activity and phytochemical analysis of ethanol extract of corn (Zea mays L.) silk

Current Research in Green and Sustainable Chemistry, 2021
In this study, ethanolic extract of Zea mays L was utilized against urinary tract infection (UTI) causing bacteria, vegetable spoilage causing fungi and anticancer activity.
S. Abirami, M. Priyalakshmi, A. Soundariya, Antony V. Samrot, S. Saigeetha, Renitta R. Emilin, S. Dhiva, L. Inbathamizh   +7 more
doaj   +1 more source

Functional Low-fat Set Yogurt Enhanced with Microbial Exo-polysaccharides-mediated Anticancer Activity [PDF]

, 2022
Exopolysaccharides (EPSs) are novel functional additives for low-fat yogurt. Pharmaceutical, medical, and food industries are using more LAB-based EPSs. In this study, Leuconostoc spp.
Mahmoud Zaki El-Readi, Khaled Elbanna, Salah Abdalrahim, Hussein H. Abulreesh, Ibrahim M. Ibrahim, Iqbal Ahmad, Abdel Naser Zohri, Manal Khider   +7 more
core   +1 more source

Anticancer Activity of 4-Aryl-1,4-Dihydropyridines

Future Pharmacology
We have synthesized 22 symmetric and asymmetric 4-aryl-1,4-dihydropyridines (1,4-DHPs) by a “green” microwave-assisted one-pot multicomponent Hantzsch reaction and evaluated their cytotoxicity to three human cancer cell lines regarding U-251MG (human ...
Thaís A. S. Oliveira, Jackson B. A. Silva, Tábata R. Esperandim, Nathália O. Acésio, Denise C. Tavares, Antônio E. M. Crotti   +5 more
doaj   +1 more source

Antioxidant, antimicrobial and anticancer activity of the lichens Cladonia furcata, Lecanora atra and Lecanora muralis

BMC Complementary and Alternative Medicine, 2011
Background The aim of this study is to investigate in vitro antioxidant, antimicrobial and anticancer activity of the acetone extracts of the lichens Cladonia furcata, Lecanora atra and Lecanora muralis. Methods Antioxidant activity was evaluated by five
Stanojković Tatjana P, Kosanić Marijana M, Ranković Branislav R   +2 more
doaj   +1 more source