Results 31 to 40 of about 6,504,034 (299)

Vitamin C and K3 Combination Causes Enhanced Anticancer Activity against RT-4 Bladder Cancer Cells [PDF]

open access: yes, 2013
Introduction: Vitamin C (VC), Vitamin K3 (VK3) and the combination (VC:VK3) were evaluated against human bladder cancer cell lines RT-4 and T24 to evaluate their synergistic anticancer activity.
Gilloteaux, Jacques   +3 more
core   +1 more source

Potential Anticancer Activity of Auranofin

open access: yesChemical and Pharmaceutical Bulletin, 2019
Gold compounds have a long history of use in medicine. Auranofin was developed more than 30 years ago as an oral therapy for rheumatoid arthritis. Now, however, auranofin is rarely used in clinical practice despite its efficacy for treating rheumatoid arthritis because more novel antirheumatic medications are available.
Onodera, Takefumi   +2 more
openaire   +5 more sources

Anticancer Activity of Papaver Somniferum

open access: yesJournal of the Turkish Chemical Society, Section A: Chemistry, 2016
This work describes the pharmacological activity of extracts of Papaver somniferum, a poppy species. P. somniferum products are still considered as a unique source of drug for many diseases.
Döne Aslı Güler   +3 more
doaj   +1 more source

Organometallic iridium(III) anticancer complexes with new mechanisms of action: NCI-60 screening, mitochondrial targeting, and apoptosis [PDF]

open access: yes, 2013
Platinum complexes related to cisplatin, cis-[PtCl2(NH3)2], are successful anticancer drugs; however, other transition metal complexes offer potential for combating cisplatin resistance, decreasing side effects, and widening the spectrum of activity ...
Hands-Portman, Ian   +5 more
core   +1 more source

Anticancer and antimicrobial activity of methoxy amino chalcone derivatives [PDF]

open access: yes, 2015
A series of methoxy amino chalcone derivatives have been synthesized and evaluated for their anticancer activity against breast cancer cells line T47D and their antimicrobial activity against Escherichia coli ATCC 25923, Staphylococcus aureus ATCC 25922,
Mustofa, .-   +4 more
core   +2 more sources

Current applications and future potential for bioinorganic chemistry in the development of anticancer drugs [PDF]

open access: yes, 2009
This review illustrates notable recent progress in the field of medicinal bioinorganic chemistry as many new approaches to the design of innovative metal-based anticancer drugs are emerging.
Rijt, Sabine H. van, Sadler, P. J.
core   +1 more source

The Spectrum of Design Solutions for Improving the Activity-Selectivity Product of Peptide Antibiotics against Multidrug-Resistant Bacteria and Prostate Cancer PC-3 Cells

open access: yesMolecules, 2020
The link between the antimicrobial and anticancer activity of peptides has long been studied, and the number of peptides identified with both activities has recently increased considerably. In this work, we hypothesized that designed peptides with a wide
Davor Juretić   +6 more
doaj   +1 more source

Understanding the Therapeutic Potential of Ascorbic Acid in the Battle to Overcome Cancer

open access: yesBiomolecules, 2021
Cancer, a fatal disease, is also one of the main causes of death worldwide. Despite various developments to prevent and treat cancer, the side effects of anticancer drugs remain a major concern.
Jurnal Reang   +3 more
doaj   +1 more source

Unusual DNA binding modes for metal anticancer complexes [PDF]

open access: yes, 2009
DNA is believed to be the primary target for many metal-based drugs. For example, platinum-based anticancer drugs can form specific lesions on DNA that induce apoptosis.
Pizarro, Ana M., Sadler, P. J.
core   +1 more source

Investigation of the key chemical structures involved in the anticancer activity of disulfiram in A549 non-small cell lung cancer cell line

open access: yesBMC Cancer, 2018
Background Disulfiram (DS), an antialcoholism medicine, demonstrated strong anticancer activity in the laboratory but did not show promising results in clinical trials. The anticancer activity of DS is copper dependent.
Kate Butcher   +6 more
doaj   +1 more source

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