Results 31 to 40 of about 333,871 (264)

Investigation of the key chemical structures involved in the anticancer activity of disulfiram in A549 non-small cell lung cancer cell line

BMC Cancer, 2018
Background Disulfiram (DS), an antialcoholism medicine, demonstrated strong anticancer activity in the laboratory but did not show promising results in clinical trials. The anticancer activity of DS is copper dependent.
Kate Butcher, Vinodh Kannappan, Rajagopal Sharada Kilari, Mark R. Morris, Christopher McConville, Angel L. Armesilla, Weiguang Wang   +6 more
doaj   +1 more source

A study on antimicrobial and anticancer properties of Cissus quadrangulris using lung cancer cell line

Cancer Treatment and Research Communications, 2023
Cissus quadrangularis plant from Vitaceae family, native in India. Many parts of this plant have medicinal values but most precious is stem of this plant.
Sholapuri Payani, Matcha Bhaskar, Gandham Sandeep Kumar, Jangampalli Adi Pradeepkiran   +3 more
doaj   +1 more source

In vitro study of pinostrobin propionate and pinostrobin butyrate: Cytotoxic activity against breast cancer cell T47D and its selectivity index

Journal of Public Health in Africa, 2023
Backgrounds: Pinostrobin has the potential activity as an anti-cancer. However, its activity is still lower than the anticancer drugs on the market. To increase its activity, pinostrobin derivatives have been synthesized, namely pinostrobin propionate ...
Tri Widiandani, Tiffany Tandian, Bagus D. Zufar, Andi Suryadi, Bambang T. Purwanto, Suko Hardjono, Siswandono Siswandono   +6 more
doaj   +1 more source

Novel Papaverine Metal Complexes with Potential Anticancer Activities

Molecules, 2020
Cancer is one of the leading causes of death worldwide. Although several potential therapeutic agents have been developed to efficiently treat cancer, some side effects can occur simultaneously.
Ahmed Gaber, Walaa F. Alsanie, Deo Nandan Kumar, Moamen S. Refat, Essa M. Saied   +4 more
doaj   +1 more source

Antimicrobial activity, antiproliferative activity, amylase inhibitory activity and phytochemical analysis of ethanol extract of corn (Zea mays L.) silk

Current Research in Green and Sustainable Chemistry, 2021
In this study, ethanolic extract of Zea mays L was utilized against urinary tract infection (UTI) causing bacteria, vegetable spoilage causing fungi and anticancer activity.
S. Abirami, M. Priyalakshmi, A. Soundariya, Antony V. Samrot, S. Saigeetha, Renitta R. Emilin, S. Dhiva, L. Inbathamizh   +7 more
doaj   +1 more source

Anticancer Activity of 4-Aryl-1,4-Dihydropyridines

Future Pharmacology
We have synthesized 22 symmetric and asymmetric 4-aryl-1,4-dihydropyridines (1,4-DHPs) by a “green” microwave-assisted one-pot multicomponent Hantzsch reaction and evaluated their cytotoxicity to three human cancer cell lines regarding U-251MG (human ...
Thaís A. S. Oliveira, Jackson B. A. Silva, Tábata R. Esperandim, Nathália O. Acésio, Denise C. Tavares, Antônio E. M. Crotti   +5 more
doaj   +1 more source

Antioxidant, antimicrobial and anticancer activity of the lichens Cladonia furcata, Lecanora atra and Lecanora muralis

BMC Complementary and Alternative Medicine, 2011
Background The aim of this study is to investigate in vitro antioxidant, antimicrobial and anticancer activity of the acetone extracts of the lichens Cladonia furcata, Lecanora atra and Lecanora muralis. Methods Antioxidant activity was evaluated by five
Stanojković Tatjana P, Kosanić Marijana M, Ranković Branislav R   +2 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Anticancer and antimicrobial activity of methoxy amino chalcone derivatives [PDF]

, 2015
A series of methoxy amino chalcone derivatives have been synthesized and evaluated for their anticancer activity against breast cancer cells line T47D and their antimicrobial activity against Escherichia coli ATCC 25923, Staphylococcus aureus ATCC 25922,
Mustofa, .-, Ni’matuzahroh, .-, Jumina, .-, Ni Nyoman Tri Puspaningsih, .-, Hery Suwito, .-   +4 more
core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source