Results 11 to 20 of about 333,871 (264)

Menthol: An underestimated anticancer agent

open access: yesFrontiers in Pharmacology, 2023
Menthol, a widely used natural, active compound, has recently been shown to have anticancer activity. Moreover, it has been found to have a promising future in the treatment of various solid tumors. Therefore, using literature from PubMed, EMBASE, Web of
Yijia Zhao   +11 more
doaj   +1 more source

Boldo phytochemical and pharmacological activities updated Mini-review [PDF]

open access: yesERU Research Journal, 2023
Peumus boldus is a plant belonging to the family Monimiaceae. It is native small perennial tree, dispersed globally, commonly known as boldo. It is distributed mainly in South America (Chile), and the Mediterranean region.
Mostafa Abouelela   +16 more
doaj   +1 more source

Anticancer Activity in Planctomycetes

open access: yesFrontiers in Marine Science, 2019
There is a strong need to develop new drugs against many severe diseases. Therapy resistance is a major problem, for instance, in infectious diseases and cancer. Drug discovery has again turned to nature to search for molecules that can become drug leads.
Rita Calisto   +8 more
doaj   +1 more source

The contrasting activity of iodido versus chlorido ruthenium and osmium arene azo- and imino-pyridine anticancer complexes : control of cell selectivity, cross-resistance, p53 dependence, and apoptosis pathway [PDF]

open access: yes, 2013
Organometallic half-sandwich complexes [M(p-cymene)(azo/imino-pyridine)X]+ where M = RuII or OsII and X ═ Cl or I, exhibit potent antiproliferative activity toward a range of cancer cells.
Sadler, P. J.   +2 more
core   +1 more source

Study of the Anticancer Potential of Plant Extracts Using Liver Tumor Microphysiological System

open access: yesLife, 2022
Background: Plants have been considered a vital source of modern pharmaceutics since the paleolithic age. Contemporary chemotherapeutic drugs for cancer therapy are chemical entities sourced from plants. However, synthetic drugs or their derivatives come
Hafiz Muhammad Umer Farooqi   +9 more
doaj   +1 more source

Organometallic half-sandwich iridium anticancer complexes [PDF]

open access: yes, 2011
The low-spin 5d6 IrIII organometallic half-sandwich complexes [(η5-Cpx)Ir(XY)Cl]0/+, Cpx = Cp*, tetramethyl(phenyl)cyclopentadienyl (Cpxph), or tetramethyl(biphenyl)cyclopentadienyl (Cpxbiph), XY = 1,10-phenanthroline (4−6), 2,2′-bipyridine (7−9 ...
Liu, Zhe   +34 more
core   +1 more source

Organometallic iridium(III) anticancer complexes with new mechanisms of action: NCI-60 screening, mitochondrial targeting, and apoptosis [PDF]

open access: yes, 2013
Platinum complexes related to cisplatin, cis-[PtCl2(NH3)2], are successful anticancer drugs; however, other transition metal complexes offer potential for combating cisplatin resistance, decreasing side effects, and widening the spectrum of activity ...
Hands-Portman, Ian   +5 more
core   +1 more source

Somatostatin subtype-2 receptor-targeted metal-based anticancer complexes [PDF]

open access: yes, 2012
Conjugates of a dicarba analogue of octreotide, a potent somatostatin agonist whose receptors are overexpressed on tumor cells, with [PtCl 2(dap)] (dap = 1-(carboxylic acid)-1,2-diaminoethane) (3), [(η 6-bip)Os(4-CO 2-pico)Cl] (bip = biphenyl, pico ...
González, Carlos A.   +24 more
core   +1 more source

Synthesis and Biological Evaluation of Novel Aminochalcones as Potential Anticancer and Antimicrobial Agents

open access: yesMolecules, 2019
A series of 18 aminochalcone derivatives were obtained in yields of 21.5−88.6% by applying the classical Claisen-Schmidt reaction. Compounds 4−9, 14 and 16−18 with 4-ethyl, 4-carboxy-, 4-benzyloxy- and 4-benzyloxy-3-methoxy groups were ...
Joanna Kozłowska   +4 more
doaj   +1 more source

ANTIOXIDANT AND ANTICANCER ACTIVITIES OF MURBEI (Morus alba L.) STEM EXTRACT ON IN VITRO WiDr CANCER CELLS

open access: yesJurnal Farmasi Sains dan Komunitas, 2020
Mulberry (Morus alba L.) is considered as an important plant in traditional Chinese medicine, due to its various compounds, including phenols and flavanoids, which have antioxidant properties so that it can be a potential anticancer candidate. This study
Asril Burhan   +4 more
doaj   +1 more source

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