Results 11 to 20 of about 5,890,540 (213)

Berberine hydrochloride: anticancer activity and nanoparticulate delivery system

open access: yesInternational Journal of Nanomedicine, 2011
Wen Tan, Yingbo Li, Meiwan Chen, Yitao WangState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao Special Administrative Region, ChinaBackground: Berberine hydrochloride is a ...
Tan W, Li YB, Chen MW, Wang YT
doaj   +2 more sources

Anacardic acid enhances the anticancer activity of liposomal mitoxantrone towards melanoma cell lines – in vitro studies

open access: yesInternational Journal of Nanomedicine, 2014
Mateusz Legut, Dominik Lipka, Nina Filipczak, Adriana Piwoni, Arkadiusz Kozubek, Jerzy GubernatorDepartment of Lipids and Liposomes, Faculty of Biotechnology, University of Wrocław, Wrocław, PolandAbstract: This paper describes a novel formulation of ...
Legut M   +5 more
doaj   +1 more source

Anticancer Activity in Planctomycetes

open access: yesFrontiers in Marine Science, 2019
There is a strong need to develop new drugs against many severe diseases. Therapy resistance is a major problem, for instance, in infectious diseases and cancer. Drug discovery has again turned to nature to search for molecules that can become drug leads.
Rita Calisto   +8 more
doaj   +1 more source

Study of the Anticancer Potential of Plant Extracts Using Liver Tumor Microphysiological System

open access: yesLife, 2022
Background: Plants have been considered a vital source of modern pharmaceutics since the paleolithic age. Contemporary chemotherapeutic drugs for cancer therapy are chemical entities sourced from plants. However, synthetic drugs or their derivatives come
Hafiz Muhammad Umer Farooqi   +9 more
doaj   +1 more source

The contrasting activity of iodido versus chlorido ruthenium and osmium arene azo- and imino-pyridine anticancer complexes : control of cell selectivity, cross-resistance, p53 dependence, and apoptosis pathway [PDF]

open access: yes, 2013
Organometallic half-sandwich complexes [M(p-cymene)(azo/imino-pyridine)X]+ where M = RuII or OsII and X ═ Cl or I, exhibit potent antiproliferative activity toward a range of cancer cells.
Sadler, P. J.   +2 more
core   +1 more source

Organometallic half-sandwich iridium anticancer complexes [PDF]

open access: yes, 2011
The low-spin 5d6 IrIII organometallic half-sandwich complexes [(η5-Cpx)Ir(XY)Cl]0/+, Cpx = Cp*, tetramethyl(phenyl)cyclopentadienyl (Cpxph), or tetramethyl(biphenyl)cyclopentadienyl (Cpxbiph), XY = 1,10-phenanthroline (4−6), 2,2′-bipyridine (7−9 ...
Liu, Zhe   +34 more
core   +2 more sources

Somatostatin subtype-2 receptor-targeted metal-based anticancer complexes [PDF]

open access: yes, 2012
Conjugates of a dicarba analogue of octreotide, a potent somatostatin agonist whose receptors are overexpressed on tumor cells, with [PtCl 2(dap)] (dap = 1-(carboxylic acid)-1,2-diaminoethane) (3), [(η 6-bip)Os(4-CO 2-pico)Cl] (bip = biphenyl, pico ...
González, Carlos A.   +24 more
core   +1 more source

Synthesis and Biological Evaluation of Novel Aminochalcones as Potential Anticancer and Antimicrobial Agents

open access: yesMolecules, 2019
A series of 18 aminochalcone derivatives were obtained in yields of 21.5−88.6% by applying the classical Claisen-Schmidt reaction. Compounds 4−9, 14 and 16−18 with 4-ethyl, 4-carboxy-, 4-benzyloxy- and 4-benzyloxy-3-methoxy groups were ...
Joanna Kozłowska   +4 more
doaj   +1 more source

ANTIOXIDANT AND ANTICANCER ACTIVITIES OF MURBEI (Morus alba L.) STEM EXTRACT ON IN VITRO WiDr CANCER CELLS

open access: yesJurnal Farmasi Sains dan Komunitas, 2020
Mulberry (Morus alba L.) is considered as an important plant in traditional Chinese medicine, due to its various compounds, including phenols and flavanoids, which have antioxidant properties so that it can be a potential anticancer candidate. This study
Asril Burhan   +4 more
doaj   +1 more source

Organometallic iridium(III) anticancer complexes with new mechanisms of action: NCI-60 screening, mitochondrial targeting, and apoptosis [PDF]

open access: yes, 2013
Platinum complexes related to cisplatin, cis-[PtCl2(NH3)2], are successful anticancer drugs; however, other transition metal complexes offer potential for combating cisplatin resistance, decreasing side effects, and widening the spectrum of activity ...
Hands-Portman, Ian   +5 more
core   +1 more source

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