Results 21 to 30 of about 11,879,963 (351)

PROFILE OF ANTICANCER ACTIVITIES OF BROTOWALI (Tinospora crispa L.) PLANTS OFVARIOUS REGIONS IN EAST JAWA

Jurnal Farmasi Sains dan Komunitas, 2020
Brotowali (Tinosporacrispa L) is a plant which has potential to be a chemopreventive agent. This study aims to determine the profile of anticancer activity of brotowali stem extracts (Tinosporacrispa L.), from several regions in East Java. The extraction
Roihatul Mutiah, Laily Nurul Azizah, Rahmi Annisa, Anik Listyana   +3 more
doaj   +1 more source

Rationally designed short cationic α-helical peptides with selective anticancer activity.

Journal of Colloid and Interface Science, 2021
HYPOTHESIS Naturally derived or synthetic anticancer peptides (ACPs) have emerged as a new generation of anticancer agents with higher selectivity for cancer cells and less propensity for drug resistance. Despite the structural diversity of ACPs, α-helix
Roja Hadianamrei, Mhd Anas Tomeh, Stephen Brown, Jiqian Wang, Xiubo Zhao   +4 more
semanticscholar   +1 more source

Persistence of anticancer activity in berry extracts after simulated gastrointestinal digestion and colonic fermentation [PDF]

, 2012
Fruit and vegetable consumption is associated at the population level with a protective effect against colorectal cancer. Phenolic compounds, especially abundant in berries, are of interest due to their putative anticancer activity.
A Gil-Izquierdo, A Gonzalez-Sarrias, A Perez-Vicente, A Petermann, Alan Crozier, AM Aura, B Holst, BN Singh, C Manach, C Parr, C Zhao, Chris I. R. Gill, Derek Stewart, DY Shin, EM Brown, EM Coates, Emma M. Brown, FJ Reyes-Zurita, FJB van Duijnhoven, G Borges, G Lala, G Williamson, Gema Pereira-Caro, GJ McDougall, GJ McDougall, Gordon J. McDougall, Ian Rowland, IT Johnson, J Ferlay, J van Duynhoven, JR Pearson, JW Yun, LA Boyd, LS Adams, M Jenner A, M Sharma, Masaru Katoh, MJ Bermudez-Soto, MJ McCann, NP Seeram, P Ramnani, Pamela Magee, PDS Spada, Philip Allsopp, PN Chen, PS Makena, R González-Barrio, Rocio González-Barrio, S Ramos, S Roowi, S Thomasset, SJ Duthie, SR Sahasrabudhe, YZ Hashim   +53 more
core   +6 more sources

Phenylselanyl Group Incorporation for “Glutathione Peroxidase-Like” Activity Modulation

Molecules, 2020
The ability of organoselenium molecules to mimic the activity of the antioxidant selenoenzyme glutathione peroxidase (GPx) allows for their use as antioxidant or prooxidant modulators in several diseases associated with the disruption of the cell redox ...
Magdalena Obieziurska-Fabisiak, Agata J. Pacuła, Lucia Capoccia, Joanna Drogosz-Stachowicz, Anna Janecka, Claudio Santi, Jacek Ścianowski   +6 more
doaj   +1 more source

Synthesis of novel fluorinated 1,5-benzothiazepine derivatives and their biological evaluation as anticancer and antibacterial agent [PDF]

Journal of the Serbian Chemical Society, 2022
A series of novel fluorinated 1,5-benzothiazepine derivatives were synthesized, characterized and evaluated for in vitro anticancer and antibacterial activity.
Bhabal Sonal R., Shaikh Sarfaraz F., Yellapurkar Ishita P., Pavale Ganesh S., Ramana Mucheli M. V.   +4 more
doaj   +1 more source

The Major Heat Shock Proteins, Hsp70 and Hsp90, in 2-Methoxyestradiol-Mediated Osteosarcoma Cell Death Model [PDF]

, 2020
2-Methoxyestradiol is one of the natural 17β-estradiol derivatives and a potential novel anticancer agent currently being under evaluation in advanced phases of clinical trials.
Cappello F., Daca A., Gorska-Ponikowska M., Kuban-Jankowska A., Luu H. H., Marino Gammazza A., Wierzbicka J. M., Wozniak M., Zmijewski M. A.   +8 more
core   +1 more source

The Therapeutic Potential of the Anticancer Activity of Fucoidan: Current Advances and Hurdles

Marine Drugs, 2021
Several types of cancers share cellular and molecular behaviors. Although many chemotherapy drugs have been designed to weaken the defenses of cancer cells, these drugs may also have cytotoxic effects on healthy tissues. Fucoidan, a sulfated fucose-based
Jun-O Jin, P. Chauhan, A. P. Arukha, Vishal Chavda, Anuj Dubey, D. Yadav   +5 more
semanticscholar   +1 more source

Synthesis of Chalcones with Anticancer Activities [PDF]

Molecules, 2012
Several chalcones were synthesized and their in vitro cytotoxicity against various human cell lines, including human breast adenocarcinoma cell line MCF-7, human lung adenocarcinoma cell line A549, human prostate cancer cell line PC3, human adenocarcinoma cell line HT-29 (colorectal cancer) and human normal liver cell line WRL-68 was evaluated. Most of
Suvitha Syam, Siddig Ibrahim Abdelwahab, Mohammed Ali Al-Mamary, Syam Mohan   +3 more
openaire   +3 more sources

Menthol: An underestimated anticancer agent

Frontiers in Pharmacology, 2023
Menthol, a widely used natural, active compound, has recently been shown to have anticancer activity. Moreover, it has been found to have a promising future in the treatment of various solid tumors. Therefore, using literature from PubMed, EMBASE, Web of
Yijia Zhao, Huafeng Pan, Wei Liu, E. Liu, Yaobin Pang, Hongjin Gao, Qingying He, Wenhao Liao, Yejing Yao, Jinhao Zeng, Jinhao Zeng, Jing Guo   +11 more
doaj   +1 more source

Docking and QSAR Studies of Camptothecin Derivatives as Inhibitor of DNA Topoisomerase-I [PDF]

, 2011
Camptothecin (CPT) is a cytotoxic quinoline alkaloid which inhibits the DNA enzyme Topoisomerase-I (Topo-I) and has shown remarkable anticancer activity in preliminary clinical trials. The major limitation is its low solubility and high adverse reaction.
Dharmendra K. Yadav, Feroz Khan, Santosh K. Srivastava   +2 more
core   +2 more sources