Results 31 to 40 of about 170,034 (262)
Proceedings, 2018 Irisin is a protein, which is encoded by the FNDC5 gene. Irisin secreted as a hormone secret via Fibronectin type III domain-containing protein 5. Irisin is always provide beneficial effect of exercise on cellular metabolism as well as obesity and ...
Işıl Yıldırım
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Computational fluid dynamics study of intra-arterial chemotherapy for oral cancer
BioMedical Engineering OnLine, 2017 Background Intra-arterial chemotherapy (IAC) for oral cancer can deliver a higher concentration of anticancer agent into a tumor-feeding artery than intravenous systemic chemotherapy. However, distribution of anticancer agent into several branches of the
Hiroaki Kitajima +6 more
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Cytotoxicity Induced by Newly Synthesized Palladium (II) Complexes Lead to the Death of MCF-7 and MDA-MB-435 Cancer Cell Lines [PDF]
Advanced Pharmaceutical Bulletin, 2023 Purpose: Breast cancer is the most common female malignancy and melanoma is the most lethal type of skin cancer. Traditional therapy for cancer treatment is far from satisfactory due to drug resistance and side effects, thus a search for new medicines is
Bruna Alexandre Oliveira da Silva +6 more
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 Isolation and identification of natural products from plants is an essential approach for discovering drug candidates. Herein we report the characterization of three sesquiterpene lactones from a new genus Shangwua, e.g. onopordopicrin (ONP), C2, and C3,
Junmin Zhang +5 more
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Casein Kinase 2 Inhibitor, CX-4945, as a Potential Targeted Anticancer Agent in Gastric Cancer [PDF]
, 2018 BACKGROUND/AIM: Casein kinase 2 (CK2) is involved in multiple cellular processes. Furthermore, its overexpression in several human cancers has been associated with tumor progression. In this study, we evaluated the efficacy of the CK2 inhibitor, CX-4945,
정민규 +5 more
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Erlotinib hydrochloride: an anticancer agent
Acta Crystallographica Section E, 2008 In the cation of the title compound, C22H24N3O4+·Cl−, an active ingredient of the anticancer drug also known as Tarceva, the quinazoline ring system is planar within 0.044 (3) Å. The dihedral angle formed by the mean planes of
K. Ravikumar +2 more
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Astragaloside IV, as a potential anticancer agent
Frontiers in Pharmacology, 2023 Cancer is a global intractable disease, and its morbidity and mortality are increasing year by year in developing countries. Surgery and chemotherapy are often used to treat cancer, but they result in unsatisfactory outcomes, such as severe side effects ...
Dongqin Xia +3 more
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Natural Product Communications, 2018 Microbial studies of soil samples collected at Ochang, Korea led to the isolation of the actinobacterium Streptomyces sp. KCB16C001. Subsequent LC/MS analysis of the culture extract for dereplication purposes enabled the identification of a new ...
Sangkeun Son +8 more
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Toxicity and Anticancer Potential of Karwinskia: A Review
Molecules, 2020 Karwinskia genus consists of shrubs and small trees. Four toxic compounds have been isolated from Karwinskia plants, which were typified as dimeric anthracenones and named T496, T514, T516, and T544. Moreover, several related compounds have been isolated
Gilberto Jaramillo-Rangel +3 more
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Repurposing Tranexamic Acid as an Anticancer Agent
Frontiers in Pharmacology, 2022 Tranexamic Acid (TA) is a clinically used antifibrinolytic agent that acts as a Lys mimetic to block binding of Plasminogen with Plasminogen activators, preventing conversion of Plasminogen to its proteolytically activated form, Plasmin. Previous studies
Mary E. Law +14 more
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