Results 41 to 50 of about 170,034 (262)
Podophyllotoxin: a novel potential natural anticancer agent [PDF]
Avicenna Journal of Phytomedicine, 2017 Objective: The aim of the present review is to give an overview about the role, biosynthesis, and characteristics of Podophyllotoxin (PTOX) as a potential antitumor agent with particular emphasis on key biosynthesis processes, function of related enzymes
Hamidreza Ardalani +2 more
doaj +1 more source
Pharmaceutics, 2023 Purine analogues are important therapeutic tools due to their affinity to enzymes or receptors that are involved in critical biological processes. In this study, new 1,4,6-trisubstituted pyrazolo[3,4-b]pyridines were designed and synthesized, and their ...
Maria Georgiou +9 more
doaj +1 more source
A Comparative Study of Cancer Cells Susceptibility to Silver Nanoparticles Produced by Electron Beam
Pharmaceutics, 2023 Introduction: Silver nanoparticles (AgNPs) have a wide range of bioactivity, which is highly dependent on particle size, shape, stabilizer, and production method.
Evgenii V. Plotnikov +6 more
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Anticancer activity of streptochlorin, a novel antineoplastic agent, in cholangiocarcinoma [PDF]
, 2015 Tae Won Kwak,1,* Hee Jae Shin,2,* Young-Il Jeong,1 Myoung-Eun Han,3 Sae-Ock Oh,3 Hyun-Jung Kim,4 Do Hyung Kim,5 Dae Hwan Kang1 1Biomedical Research Institute, Pusan National University Hospital, Busan, 2Marine Natural Products Chemistry Laboratory ...
Jeong YI +7 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Molecules, 2021 The development of cancer treatments requires continuous exploration and improvement, in which the discovery of new drugs for the treatment of cancer is still an important pathway.
Shicheng Hou +9 more
doaj +1 more source
BPR0C305, an orally active microtubule-disrupting anticancer agent [PDF]
, 2013 [[abstract]]BPR0C305 is a novel N-substituted indolyl glyoxylamide previously reported with in-vitro cytotoxic activity against a panel of human cancer cells including P-gp-expressing multiple drug-resistant cell sublines.
Li, WT;Yeh, TK;Song, JS;Yang, YN;Chen, TW;Lin, CH;Chen, CP;Shen, CC;Hsieh, CC;Lin, HL;Chao, YS;Chen, CT
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Design and Synthesis of Anti-Cancer Chimera Molecules Based on Marine Natural Products
Marine Drugs, 2019 In this paper, the chemical conjugation of marine natural products with other bioactive molecules for developing an advanced anti-cancer agent is described.
Min Woo Ha +3 more
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Journal of Pure and Applied Microbiology, 2022 Human beings are affected by different diseases and suffer to different extents. Cancer is one of the major human disease and millions of people suffered from cancer and end their lives every year.
Sanjib Kalita +5 more
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