Results 31 to 40 of about 322,983 (366)

Heparin Mimetics: Their Therapeutic Potential

open access: yesPharmaceuticals, 2017
Heparin mimetics are synthetic and semi-synthetic compounds that are highly sulfated, structurally distinct analogues of glycosaminoglycans. These mimetics are often rationally designed to increase potency and binding selectivity towards specific ...
Shifaza Mohamed, Deirdre R. Coombe
doaj   +1 more source

Anticoagulant status under COVID-19: The potential pathophysiological mechanism

open access: yesJournal of Applied Hematology, 2022
Coronavirus disease 19 (COVID-19) is a systematic multitropic disease. Sustaining blood homeostasis is a mission of multiple factors includes procoagulant and anticoagulant systems.
Basheer Abdullah Marzoog
doaj   +1 more source

Synthetic polymers with anticoagulant activity [PDF]

open access: yes, 1979
Polymers with C=C bonds have been modified by reaction with chlorosulfonyl isocyanate (CSI). Addition products were obtained in yields varying from 60% to 75%.
Bantjes, A.   +3 more
core   +2 more sources

Anticoagulants [PDF]

open access: yesBritish Medical Bulletin, 2000
Anticoagulation is a treatment with significant and life threatening complications requiring that the balance of risk and benefit be individually assessed in each patient. The risks are greater in the elderly and those with hypertension, falls and gastrointestinal disease.
openaire   +2 more sources

An Albumin-Oligonucleotide Assembly for Potential Combinatorial Drug Delivery and Half-Life Extension Applications

open access: yesMolecular Therapy: Nucleic Acids, 2017
The long blood circulatory property of human serum albumin, due to engagement with the cellular recycling neonatal Fc receptor (FcRn), is an attractive drug half-life extension enabling technology. This work describes a novel site-specific albumin double-
Matthias Kuhlmann   +12 more
doaj   +1 more source

Prediction of need for bowel resection in acute superior mesenteric artery occlusion: A retrospective study of 48 Japanese patients

open access: yesAnnals of Gastroenterological Surgery, Volume 7, Issue 1, Page 175-181, January 2023., 2023
In a study of 48 patients with acute superior mesenteric artery occlusion, a logistic regression model using time from onset to diagnosis and the occlusion site of superior mesenteric artery showed 78.6% sensitivity in ruling out cases requiring bowel resection.
Susumu Watada   +9 more
wiley   +1 more source

How we treat bleeding associated with direct oral anticoagulants [PDF]

open access: yes, 2016
Direct oral anticoagulants are at least as effective as vitamin K antagonists for the prevention and treatment of thromboembolism. Unfortunately, differently from vitamin K antagonists, they have the great drawback of lacking specific antidotes in the ...
Franchini, Massimo   +4 more
core   +1 more source

Therapeutic Interchange of Parenteral Anticoagulants: Challenges for Pharmacy and Therapeutics Committees

open access: yesPharmaceuticals, 2011
This is a review of key factors for pharmacy and therapeutics committees to consider when developing a therapeutic interchange (TI) program for venous thromboembolism (VTE) prophylaxis. Recent patient safety initiatives aimed at reducing the incidence of
Alpesh Amin
doaj   +1 more source

Integrating complex selection rules into the latent overlapping group Lasso for constructing coherent prediction models [PDF]

open access: yesarXiv, 2022
The construction of coherent prediction models holds great importance in medical research as such models enable health researchers to gain deeper insights into disease epidemiology and clinicians to identify patients at higher risk of adverse outcomes.
arxiv  

Update on Extended Treatment for Venous Thromboembolism [PDF]

open access: yes, 2018
The importance of assessing the probability of venous thromboembolism recurrence, a condition that includes deep vein thrombosis and pulmonary embolism, lies in the fact that it is the most important factor in deciding the duration of anticoagulant ...
Del Toro-Cervera, Jorge   +7 more
core   +2 more sources

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