Lupus anticoagulant testing during anticoagulation, including direct oral anticoagulants
Lupus anticoagulants (LA) are one laboratory criterion for classification of antiphospholipid syndrome, with presence of vascular thrombosis and/or pregnancy/fetal morbidity being clinical criteria. The presence of LA is detected (or excluded) by laboratory testing, with the activated partial thromboplastin time and dilute Russell's viper venom time ...
Emmanuel J. Favaloro, Leonardo Pasalic
openaire +3 more sources
BackgroundD-dimer is a biomarker of fibrin production and degradation, and changes in D-dimer concentration suggest fibrin clot formation, which is associated with thromboembolism and hypercoagulable states.
Shohei Migita+11 more
doaj +1 more source
Large-scale structure of brown rat (Rattus norvegicus) populations in England: effects on rodenticide resistance [PDF]
The brown rat (Rattus norvegicus) is a relatively recent (
Adams, Sally+6 more
core +2 more sources
Assessment of factors affecting mortality in geriatric patients with warfarin overdose
OBJECTIVES: The aim of the present study was to perform a demographic analysis of complications and to determine the factors affecting in-hospital mortality in geriatric patients with warfarin overdose.
Seda Dagar+3 more
doaj +1 more source
Experimental antithrombotic effect of medicinal plants: A critical review
Thrombosis is one of the major causes of morbidity and mortality in a wide range of cardiovascular disorders (CVDs). CVDs are listed among top ten killer diseases. Antithrombotic drugs reduce the incidence of cardiovascular events about 20%–25% in people.
Shweta Mandloi+2 more
doaj +1 more source
Cost‐effectiveness of second‐line therapies in adults with chronic immune thrombocytopenia
Abstract Major options for second‐line therapy in adults with chronic immune thrombocytopenia (ITP) include splenectomy, rituximab, and thrombopoietin receptor agonists (TRAs). The American Society of Hematology guidelines recommend rituximab over splenectomy, TRAs over rituximab, and splenectomy or TRAs while noting a lack of evidence on the cost ...
George Goshua+5 more
wiley +1 more source
Efficacy, Safety, and Timing of Anticoagulant Thromboprophylaxis for the Prevention of Venous Thromboembolism in Patients With Acute Spinal Cord Injury: A Systematic Review [PDF]
Study Design: Systematic review. Objectives: The objective of this study was to answer 5 key questions: What is the comparative effectiveness and safety of (1a) anticoagulant thromboprophylaxis compared to no prophylaxis, placebo, or another ...
Arnold, Paul M.+10 more
core +2 more sources
Anticoagulant Rodenticides, Islands and Animal Welfare Accountancy
Anticoagulant rodenticides are used to manage rodents in domestic, municipal, agricultural, and conservation settings. In mammals and birds, anticoagulant poisoning causes extensive hemorrhagic disruption, with the primary cause of death being severe ...
Penny Fisher+3 more
doaj +1 more source
Anticoagulants for acute ischaemic stroke [PDF]
Peer reviewedPublisher ...
Counsell, Carl+2 more
core +1 more source
Two SOX11 variants cause Coffin–Siris syndrome with a new feature of sensorineural hearing loss
Abstract Coffin‐Siris syndrome (CSS, OMIM#135900) is a rare congenital disorder associated with neurodevelopmental and dysmorphic features. The primary cause of CSS is pathogenic variants in any of 9 BAF chromatin‐remodeling complex encoding genes or the genes SOX11 and PHF6. Herein, we performed whole‐exome sequencing (WES) and a series of analyses of
Qiuquan Wang+5 more
wiley +1 more source