Results 71 to 80 of about 346,610 (333)

Assessment of factors affecting mortality in geriatric patients with warfarin overdose

Turkish Journal of Emergency Medicine, 2020
OBJECTIVES: The aim of the present study was to perform a demographic analysis of complications and to determine the factors affecting in-hospital mortality in geriatric patients with warfarin overdose.
Seda Dagar, Emine Emektar, Hüseyin Uzunosmanoglu, Yunsur Cevik   +3 more
doaj   +1 more source

Anticoagulant therapy with fondaparinux in a liver transplant patient with thrombosis and liver fibrosis: a case report [PDF]

, 2017
The treatment with fondaparinux is the effective and safe anticoagulant therapy in liver transplant patient on immunosuppressive therapy with arterial thrombosis, and it seems able to reduce liver fibrosis.
Cafolla, Arturo, Gentile, Giuseppe
core   +1 more source

Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy

Advanced Healthcare Materials, EarlyView.
This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley   +1 more source

Preclinical Evaluation of the Anticoagulant Effect of an Aqueous Extract of Snow Mountain Garlic

Medicina
Background/Objectives: In the genus Allium, it has been shown that some organosulfate compounds of common garlic and onion have an antiplatelet effect.
Isabel Clark-Montoya, Rosa del Carmen Milán-Segovia, Obed Lemus-Rojero, Osmar Antonio Jaramillo-Morales, Bertha Júarez-Flores, Yolanda Terán-Figueroa   +5 more
doaj   +1 more source

Programmable Compliance in Small‐Diameter Vascular Grafts by Design of Melt‐Electrowritten Scaffold Architectures for In Situ Tissue Engineering

Advanced Healthcare Materials, EarlyView.
Small‐diameter vascular grafts with compliance tunable by design are fabricated via melt electrowriting. By controlling the winding angle of intertwined helical fibers, grafts with compliances matching those of human vessels, from veins to arteries, are realized. This holds the potential of avoiding a compliance mismatch, which has been identified as a
Kilian Maria Arthur Mueller, Christina Ahrens, Linda Grefen, Salma Mansi, Dario Arcuti, Elena De‐Juan‐Pardo, Felix Kur, Christian Hagl, Petra Mela   +8 more
wiley   +1 more source

Low concentrations of recombinant activated factor VII normalize coagulation patterns by reversing the changes in viscoelastic testing parameters induced by abelacimab in vitro

Research and Practice in Thrombosis and Haemostasis
Background: Low doses of recombinant activated factor (F)VII (rFVIIa), used to manage bleeding in patients with severe FXI deficiency, have been proposed to bypass effects of the FXI/FXIa inhibitor abelacimab.
Yasser Khder, Serge Côté, Klaus Peter Hoffmann, Debra Freedholm, Dan Bloomfield, Jean M. Connors   +5 more
doaj   +1 more source

Uniting 4D Printing and Melt Electrowriting for the Enhancement of Regenerative Small Diameter Vascular Grafts

Advanced Healthcare Materials, EarlyView.
A hybrid 4D printing strategy enables the fabrication of shape‐morphing, mechanically reinforced tubular constructs for vascular tissue engineering. By combining alginate‐methylcellulose hydrogels with melt electrowritten polycaprolactone fibers and protein‐based functionalization, this platform supports spatially organized co‐cultures of fibroblasts ...
Max von Witzleben, Akvilė Gasiūnaitė, Marlene Ihle, Ashwini Rahul Akkineni, Kathleen Schütz, Tilman Ahlfeld, Michael Gelinsky, Anja Lode, Sarah Duin   +8 more
wiley   +1 more source

New oral anticoagulants and their reversal agents [PDF]

, 2018
Atrial fibrillation is a commonly encountered pathology in medical practice, and its prevalence has shown a continuous rise over the past years. Atrial fibrillation has a significant impact on patients\u27 quality of life, not only due to the standard ...
Bodean, Oana, Diaconu, Camelia C, Laslo, Crista L, Marcu, Dragos, Neagu, Tiberiu P, Paduraru, Dan N, Pantea Stoian, Anca, Socea, Bogdan, Socea, Laura I, Stanescu, Ana Maria Alexandra   +9 more
core   +1 more source

A Robust Heparin‐Mimicking Polyglycerol‐Based Coating for Blood‐Contacting Devices with Long‐Term Hemocompatibility and Preliminary Anti‐Inflammatory Properties

Advanced Healthcare Materials, EarlyView.
A robust heparin‐mimicking coating based on sulfated polyglycerol is constructed via layer‐by‐layer assembly on bloodcontacting surfaces. The coating exhibits long‐term anticoagulant and anti‐inflammatory properties by resisting protein adsorption, preventing platelet activation, and suppressing immune responses, offering a promising strategy for ...
Kunpeng Liu, Philip Nickl, Jun Feng, Rainer Haag   +3 more
wiley   +1 more source

Safety and preliminary efficacy of argatroban plus dual antiplatelet therapy for acute mild to moderate ischemic stroke with large artery atherosclerosis

Brain and Behavior, 2022
Objective Previous studies suggest the benefit of dual antiplatelet therapy (DAPT) for acute ischemic stroke with large artery atherosclerosis (LAA) etiology, but there is no study about the effect of DAPT plus anticoagulant in this population. Methods A
Xiao‐Qiu Li, Xiao‐Wen Hou, Yu Cui, Xiao‐Fu Tian, Xin‐Hong Wang, Zhong‐He Zhou, Hui‐Sheng Chen   +6 more
doaj   +1 more source