Results 1 to 10 of about 325,134 (291)
JAMA Neurology, 2023 Key Points Question Is the recent use of direct oral anticoagulants (confirmed ingestion within 48 hours) associated with increased risk of symptomatic intracranial hemorrhage following intravenous thrombolysis for ischemic stroke?
T. Meinel +224 more
semanticscholar +1 more source
Anticoagulants: A Short History, Their Mechanism of Action, Pharmacology, and Indications
Cells, 2022 Anticoagulant drugs antagonize coagulation and are used to prevent or cure (recurrent) venous thromboembolism (VTE). Drugs to prevent clotting have been used for more than a century, and, nowadays, physicians possess a broad panel of multiple ...
Marco Heestermans +4 more
semanticscholar +1 more source
Anticoagulants for people hospitalised with COVID-19.
Cochrane Database of Systematic Reviews, 2022 BACKGROUND The primary manifestation of coronavirus disease 2019 (COVID-19) is respiratory insufficiency that can also be related to diffuse pulmonary microthrombosis and thromboembolic events, such as pulmonary embolism, deep vein thrombosis, or ...
Ronald Lg Flumignan +9 more
semanticscholar +1 more source
Factor XI as a Target for New Anticoagulants
Hämostaseologie, 2021 Despite advances in anticoagulant therapy, thrombosis remains the leading cause of morbidity and mortality worldwide. Heparin and vitamin K antagonists (VKAs), the first anticoagulants to be used successfully for the prevention and treatment of ...
J. Fredenburgh, J. Weitz
semanticscholar +1 more source
Lupus anticoagulant testing during anticoagulation, including direct oral anticoagulants
Research and Practice in Thrombosis and Haemostasis, 2022 Lupus anticoagulants (LA) are one laboratory criterion for classification of antiphospholipid syndrome, with presence of vascular thrombosis and/or pregnancy/fetal morbidity being clinical criteria. The presence of LA is detected (or excluded) by laboratory testing, with the activated partial thromboplastin time and dilute Russell's viper venom time ...
Emmanuel J. Favaloro, Leonardo Pasalic
openaire +3 more sources
Outcomes Associated With Oral Anticoagulants Plus Antiplatelets in Patients With Newly Diagnosed Atrial Fibrillation. [PDF]
, 2020 Importance: Patients with nonvalvular atrial fibrillation at risk of stroke should receive oral anticoagulants (OAC). However, approximately 1 in 8 patients in the Global Anticoagulant Registry in the Field (GARFIELD-AF) registry are treated with ...
Bassand, J-P +17 more
core +2 more sources
Patient safety and estimation of renal function in patients prescribed new oral anticoagulants for stroke prevention in atrial fibrillation [PDF]
, 2013 OBJECTIVE: In clinical trials of dabigatran and rivaroxaban for stroke prevention in atrial fibrillation (AF), drug eligibility and dosing were determined using the Cockcroft-Gault equation to estimate creatine clearance as a measure of renal function ...
Ashman, N +6 more
core +2 more sources
How we treat bleeding associated with direct oral anticoagulants [PDF]
, 2016 Direct oral anticoagulants are at least as effective as vitamin K antagonists for the prevention and treatment of thromboembolism. Unfortunately, differently from vitamin K antagonists, they have the great drawback of lacking specific antidotes in the ...
Franchini, Massimo +4 more
core +1 more source
Anticoagulants for acute ischaemic stroke [PDF]
, 2015 Peer reviewedPublisher ...
Counsell, Carl +2 more
core +1 more source
Journal of Thrombosis and Haemostasis, 2020 Clarity and guidance is required with regard to the use of direct oral anticoagulants in antiphospholipid syndrome (APS) patients, within the confines of the recent European Medicines Agency recommendations, discrepant recommendations in other ...
S. Zuily +11 more
semanticscholar +1 more source