Results 111 to 120 of about 128,931 (391)

Exploring Valeriana species: Unraveling anticonvulsant potential through phytochemistry and pharmacology

open access: yesFuture Natural Products
Background and aims: The Valerianaceae comprises about 300 species of annual and perennial plants found worldwide. Several species are utilized for biological purposes, while others are consumed.
Mohammad Amin Manavi
doaj   +1 more source

Seizure threshold, hormones and anti epileptic drugs

open access: yesUniversa Medicina, 2008
The concept of seizure threshold holds that everyone has a certain balance between excitatory and inhibitory forces in the brain. A low seizure threshold makes it easier for epilepsy to develop and easier for someone to elicit single seizure.
Harsono Harsono
doaj   +1 more source

Synthesis and Biological Evaluation of Some [1,2,4]Triazolo[4,3-a]quinoxaline Derivatives as Novel Anticonvulsant Agents

open access: yesISRN Organic Chemistry, 2013
2-([1,2,4]Triazolo[4,3-a]quinoxalin-4-ylthio)acetic acid hydrazide (10) was used as a precursor for the syntheses of novel quinoxaline derivatives with potential anticonvulsant properties. The newly synthesized compounds have been characterized by IR, 1H 
Mohamed Alswah   +3 more
semanticscholar   +1 more source

The simultaneous effect of valproic acid and gamma radiation on telomerase activity and bax and Bcl-2 protein levels in MCF-7 breast cancer cell line [PDF]

open access: yes, 2015
Background: Breast cancer is one of the most prevalent types of cancer. Factors such as ionizing radiation and chemotherapeutic agents can trigger apoptosis and cancer cell death.
Asadi, J.   +3 more
core   +1 more source

Removal of benzotriazoles from domestic wastewater using Pleurotus ostreatus fungal pellets

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Removal of benzotriazoles from domestic wastewater using a fungal pellet reactor with Pleurotus ostreatus. The system effectively removed CBTR (70%), while BTR (19%), 5‐TTR (17%), and OH‐BTH (16%) showed moderate removal. Abstract Benzotriazoles are a group of persistent and mobile substances commonly found in aquatic environments due to inefficient ...
Evrydiki Markoulatou   +3 more
wiley   +1 more source

Cyclooxygenase-1 as a potential therapeutic target for seizure suppression: evidences from zebrafish pentylenetetrazole-seizure model

open access: yesFrontiers in Neurology, 2016
Cyclooxygenases (COX) -1 and -2 are isoenzymes that catalyze the conversion of arachidonic acid into prostaglandins (PGs). COX-2 and PGs are rapidly increased following seizures and are known to play important roles in the neuroinflammatory process.
Patricia Gonçalves Barbalho   +3 more
doaj   +1 more source

New Aspects of Thromboangiitis obliterans (von Winiwarter-Buerger's Disease) [PDF]

open access: yes, 1984
The existence of thromboangiitis obliterans as a clinical entity has been a matter of debate for many years. In contrast to other immunovasculitides there is no organ involvement while peripheral vessels are affected.
Berlit, Peter   +3 more
core   +1 more source

Phenobarbital Bioequivalence in Chinese Population: Considering the Role of Food on Pharmacokinetics

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Epilepsy is one of the most severe neurological disorders in the world, which might seriously endanger the lives of patients. Phenobarbital is an important medicine clinically used for the treatment of epilepsy, and it is irreplaceable in the treatment of generalized tonic–clonic seizures, focal seizures, status epilepticus, and pediatric ...
Wang Xinman   +3 more
wiley   +1 more source

Seizure Disorders in Goats and Sheep. [PDF]

open access: yes, 2016
BackgroundGoats and sheep are more likely to be presented for examination for seizures than are cattle, possibly as a consequence of their relatively smaller body size.
Aleman, M, Chigerwe, M
core   +1 more source

Impact of Halogen Substituent Nature and Position on the Structural and Energetic Properties of Carbamazepine Cocrystals with Meta‐Halobenzoic Acids: A Two‐Pathway Synthesis Study

open access: yesChemPlusChem, EarlyView.
This study explores how halogen substitution in benzoic acid coformers affects the structure and stability of carbamazepine cocrystals. Isostructurality and enhanced lattice stability with heavier halogens are revealed, highlighting key supramolecular interactions.
Artur Mirocki, Mattia Lopresti
wiley   +1 more source

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