Results 141 to 150 of about 131,323 (382)

Self‐completed patient‐reported outcome measures in adults with epilepsy: A review

Epilepsia Open, EarlyView.
Abstract Epilepsy affects 65 million people worldwide, and is a World Health Organization priority disease as highlighted in their 2022–2031 Intersectoral Global Action Plan (IGAP) on Epilepsy and other Neurological Disorders. IGAP's objectives include improving epilepsy treatment and care.
Alison L. Conquest, Terence J. O'Brien, Patrick Kwan, Jacqueline A. French, Charles B. Malpas, Emma C. Foster   +5 more
wiley   +1 more source

Lacosamide in the Treatment of Trigeminal Neuralgia Refractory to Conventional Treatment Due to Severe Leukopenia Induced by Anticonvulsants [PDF]

, 2019
Noemi Coppola, Elena Calabria, Giulio Fortuna, Elvira Ruoppo, Marco Caparrotti, Daniela Adamo   +5 more
openalex   +1 more source

Epilepsy surgery: From bench to the clinics

Epilepsia Open, EarlyView.
Abstract Objective Recent advances in epilepsy surgery in patients with intractable epilepsy make it possible to study the mechanism of epilepsy in human brains. However, the true extent and propagation of each epileptogenic area from the epileptogenic focus in each patient is still difficult to perform “epilepsy cure” by surgery.
Tatsuya Tanaka
wiley   +1 more source

Clock gene dysregulation in epilepsy: A systematic review

Epilepsia Open, EarlyView.
Abstract Objective Epileptic seizures show a rhythmic pattern, being more frequent at particular times of the day (e.g., only occurring during sleep), suggesting a role of the circadian rhythm. Clock genes regulate the circadian rhythm and might be involved in the pathophysiology of epilepsy.
Guilherme Fernandes‐Campos, Arjune Sen, Francesca Panin, Krithika Sundararaman   +3 more
wiley   +1 more source

Clinical outcomes and learning curve of MRgLITT system for drug‐resistant epilepsy in China: A single‐center retrospective study

Epilepsia Open, EarlyView.
Abstract Objective Magnetic resonance‐guided laser interstitial thermal therapy (MRgLITT) is a minimally invasive technique that allows for real‐time magnetic resonance imaging (MRI) monitoring and precise ablation of epileptogenic lesions. This study reports our initial clinical experience with a domestically developed MRgLITT system in patients with ...
Sichang Chen, Yang Dai, Xiaotong Fan, Yihe Wang, Penghu Wei, Yongzhi Shan, Guoguang Zhao   +6 more
wiley   +1 more source

Efficacy and Safety of Lisdexamfetamine Versus Topiramate Versus Naltrexone/Bupropion in Individuals With Binge Eating Disorder: A Network Meta‐Analysis

European Eating Disorders Review, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of lisdexamfetamine, topiramate, and naltrexone/bupropion for treating binge eating disorder (BED) using network meta‐analysis. Method We systematically searched PubMed, Scopus, ClinicalTrials.gov, and Cochrane Central up to February 2025 for randomized controlled trials evaluating these medications
Tamer Hodrob, Ibrahim Ismail, Alaaeddin Abusalameh, Celina R. Andonie, Omar Ayesh, Hazem Ayesh   +5 more
wiley   +1 more source

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

Proceedings of the National Academy of Sciences of the United States of America, 1986
E. Wong, J. Kemp, T. Priestley, A. R. Knight, G. Woodruff, L. Iversen   +5 more
semanticscholar   +1 more source

ANTICONVULSANT POTENCY OF 10 VARIOUS P-ISOPROPOXYPHENYLSUCCINIMIDE DERIVATIVES IN THE MAXIMAL ELECTROSHOCK-INDUCED SEIZURE THRESHOLD MODEL IN MICE [PDF]

, 2017
S. L. Kocharov, Henry A. Panosyan, Paweł Marzęda, Paula Wróblewska-Łuczka, Ewelina Kochman, Aleksandra Właź, Jarogniew J. Łuszczki   +6 more
openalex   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source