Results 161 to 170 of about 72,257 (246)

Nerve conduction velocity in patients under longterm treatment with antiepileptic drugs [PDF]

, 1990
Berlit, Peter, Krause, Klaus-Henning
core  

Spasmodic Dysphonia

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Spasmodic dysphonia is a laryngeal dystonia that can present as adductor, abductor, or mixed types, with or without tremor. The etiology is not understood fully. Comprehensive evaluation is required to establish the diagnosis. Treatments include voice therapy, medications, botulinum toxin injection, laryngeal surgery, deep brain stimulation ...
Aaron J. Jaworek, Robert T. Sataloff
wiley   +1 more source

The potential of dibenzazepine carboxamides in cancer therapy. [PDF]

Front Pharmacol
Afsordeh N, Pournajaf S, Mirnajafi-Zadeh J, Pourgholami MH.   +3 more
europepmc   +1 more source

Effects of sodium fluoride on serum concentrations of selected psychotropic drugs

Journal of Forensic Sciences, EarlyView.
Abstract Caution is imperative when interpreting drug concentrations in blood, plasma, or serum, given the potential variance in the distribution of a compound across these fluids. Preservatives, such as sodium fluoride, prove beneficial in preventing drug degradation in collected blood samples. This study aimed to examine the impact of sodium fluoride
Jennifer Liut, Julian Prangenberg, Michael Krämer, Alexandra Maas‐Gramlich, Peter Heese, Markus Banger, Burkard Madea   +6 more
wiley   +1 more source

Biological Activity of Monoterpene-Based Scaffolds: A Natural Toolbox for Drug Discovery. [PDF]

Molecules
Mołdoch J, Agacka-Mołdoch M, Jóźwiak G, Wojtunik-Kulesza K.   +3 more
europepmc   +1 more source

Biomarkers of Cellular Senescence in Type 2 Diabetes Mellitus

Aging Cell, EarlyView.
In cohorts of lean controls, obese participants without Type 2 Diabetes Mellitus (T2DM) and obese T2DM participants, we find that T‐cell expression of senescence biomarkers is altered only in the T2DM participants and not with obesity alone. Moreover, high T‐cell p16 expression in the T2DM participants is associated with impaired bone cortical indices.
Caroline Hoong, Joshua N. Farr, David G. Monroe, Thomas A. White, Elizabeth J. Atkinson, Amanda Tweed, Allyson K. Palmer, Nathan K. LeBrasseur, Jad G. Sfeir, Sundeep Khosla   +9 more
wiley   +1 more source

Piracetam as Neuroprotective, Anticonvulsant, and Anti-Anxiety Agent: An <i>In Vivo</i> Study on Ptz Epileptic Rats. [PDF]

Arch Razi Inst
Karimi Shayan T, Abdolmaleki A, Asadi A, Hassanpour H.   +3 more
europepmc   +1 more source

Moderation of treatment outcomes by polygenic risk for alcohol‐related traits in placebo‐controlled trials of topiramate

Alcohol, Clinical and Experimental Research, EarlyView.
In a secondary analysis of data from two randomized controlled trials of topiramate in 285 individuals with alcohol use disorder (AUD), measures of genetic risk for problematic alcohol use (PAU) and time to relapse to any drinking (TR) and heavy drinking (THR) significantly moderated topiramate's effect on alcohol‐related problems.
Henry R. Kranzler, Zeal Jinwala, Christal N. Davis, Heng Xu, Joanna M. Biernacka, Hang Zhou, Rachel L. Kember, Joel Gelernter, Richard Feinn   +8 more
wiley   +1 more source

Anticonvulsant Effects of Synthetic <i>N</i>-(3-Methoxybenzyl)oleamide and <i>N</i>-(3-Methoxybenzyl)linoleamide Macamides: An In Silico and In Vivo Study. [PDF]

Molecules
Vera-López KJ, Aguilar-Pineda JA, Moscoso-Palacios RM, Davila-Del-Carpio G, Manrique-Murillo JL, Gómez B, González-Melchor M, Nieto-Montesinos R.   +7 more
europepmc   +1 more source

Multi‐ancestry genome‐wide association study of topiramate's effects on heavy alcohol use

Alcohol, Clinical and Experimental Research, EarlyView.
Topiramate reduces alcohol consumption, but genetic predictors of treatment response have not been identified. We conducted a GWAS in 8386 individuals from the Million Veteran Program, evaluating genetic variants associated with the change in alcohol consumption before and after initiating topiramate.
Christal N. Davis, Zeal Jinwala, Amy C. Justice, Christopher T. Rentsch, Henry R. Kranzler   +4 more
wiley   +1 more source