The Novel Anticonvulsant Drug, Gabapentin (Neurontin), Binds to the Subunit of a Calcium Channel (*)
Journal of Biological Chemistry, 1996 Gabapentin (1-(aminomethyl)cyclohexane acetic acid; Neurontin) is a novel anticonvulsant drug, with a mechanism of action apparently dissimilar to that of other antiepileptic agents.
N. Gee +5 more
semanticscholar +1 more source
Posterior Reversible Encephalopathy Syndrome and Azathioprine [PDF]
, 2019 Posterior reversible encephalopathy syndrome (PRES) is a rare syndrome that presents with neurological manifestations, often associated with arterial hypertension.
Corte-Real, A, Vilas-Boas, S
core +2 more sources
Frontiers in Pharmacology, 2014 Alpha (α)-asarone, a major effective component isolated from the Chinese medicinal herb Acorus tatarinowii, is clinically used as medication for treating epilepsy, cough, bronchitis, and asthma.
Ze-Jun eWang +3 more
doaj +1 more source
Comparison of Magnesium Sulphate Protocols by Weight-Adjusted Versus Two Grams Per Hour for Preventing Convulsion in Preeclampsia: A Randomised Controlled Trial [PDF]
Journal of Clinical and Diagnostic Research, 2019 Introduction: Magnesium Sulphate (MgSO4 ) is the most effective drug used for seizure prevention in preeclampsia; however, the dosage of MgSO4 is still in controversy.
Saowanee Tangmanowutthikul +3 more
doaj +1 more source
Therapeutic effects of rosemary (Rosmarinus officinalis L.) and its active constituents on nervous system disorders [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Rosemary (Rosmarinus officinalis L.) is an evergreen bushy shrub which grows along the Mediterranean Sea, and sub-Himalayan areas. In folk medicine, it has been used as an antispasmodic, mild analgesic, to cure intercostal neuralgia, headaches, migraine,
Mahboobeh Ghasemzadeh Rahbardar +1 more
doaj +1 more source
NGX-4010, a capsaicin 8% patch, for the treatment of painful HIV-associated distal sensory polyneuropathy: integrated analysis of two phase III, randomized, controlled trials [PDF]
, 2013 BACKGROUND HIV-associated distal sensory polyneuropathy (HIV-DSP) is the most frequently reported neurologic complication associated with HIV infection.
Brew, Bruce J +9 more
core +1 more source
When Cellulose Moves: Smart Sensors and Actuators
Advanced Materials Technologies, EarlyView.This review highlights cellulose‐derived soft actuators alongside with cellulose‐based sensors. Emphasis is placed on their integration into multifunctional devices that couple sensing and actuation to mimic natural motion and adaptability. We also discuss the challenges of achieving robust, reversible, and multi‐stimuli‐responsive motion, and outline ...
Francisco Sousa +2 more
wiley +1 more source
How Can Network-Pharmacology Contribute to Antiepileptic Drug Development? [PDF]
, 2014 Network-pharmacology is a field of pharmacology emerging from the observation that most clinical drugs have multiple targets, contrasting with the previously dominant magic bullet paradigm which proposed the search of exquisitely selective drugs. What is
Di Ianni, Mauricio Emiliano +1 more
core +1 more source
Medical Materials and Device Innovation: Choosing the Right and Relevant Biological Models
Advanced Therapeutics, EarlyView.Choosing the right disease model is key to safe, effective medical innovation. When models reflect human biology and clinical needs, they improve translation, reduce risk, and accelerate progress. Advances in 3D tissues, organ‐on‐chip, and humanized systems offer exciting opportunities. With thoughtful selection and clinician input, biomedical research
Inge K. Herrmann +1 more
wiley +1 more source
Cancer Neuroscience: Decoding Neural Circuitry in Tumor Evolution for Targeted Therapy
Advanced Science, EarlyView.This review highlights the pivotal role of the nervous system in cancer progression, emphasizing how neural–tumor interactions—via synaptic signaling, neurotransmitters, and paracrine factors—reshape the tumor microenvironment. It introduces cancer neuroscience as an emerging field and proposes integrating advanced tools such as AI and optogenetics to ...
Mengyu Yuan +4 more
wiley +1 more source