Results 61 to 70 of about 78,762 (304)
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Heterozygous variants in the AHDC1 gene are associated with Xia Gibbs Syndrome (XGS), a genetic disorder with a highly variable phenotype. Cognitive impairment, motor delay, language delay, neonatal hypotonia, and sleep apnea are considered “cardinal” signs of the disease.
Giulia Cinelli +18 more
wiley +1 more source
Фармакокинетика и Фармакодинамика, 2017 The study was aimed to compare the psychopharmacological effects of 2 anticonvulsant drugs levetiracetam ((S)-2-(2-oxopyrrolidin-1-yl) butanamide) and the new compound, GIZh-290 (2-oxo-4-phenylpyrrolidine-1-yl) acetic acid) on behavioral spectra of ...
I. G. Kovalev +4 more
doaj
Evaluation of Clematis hedysarifolia DC. for potential anticonvulsant activity in Pentylenetetrazol and Strychnine induced convulsion in albino mice [PDF]
International Journal of Minor Fruits, Medicinal and Aromatic PlantsJuice of Clematis hedysarifolia DC, has been employed in the treatment of seizures and various neurological disorders. Research objective was to examine anticonvulsant effects of different solvent extracts of leaf and stem parts of Clematis hedysarifolia
Sonali Gawali
doaj +1 more source
Comparison of Magnesium Sulphate Protocols by Weight-Adjusted Versus Two Grams Per Hour for Preventing Convulsion in Preeclampsia: A Randomised Controlled Trial [PDF]
Journal of Clinical and Diagnostic Research, 2019 Introduction: Magnesium Sulphate (MgSO4 ) is the most effective drug used for seizure prevention in preeclampsia; however, the dosage of MgSO4 is still in controversy.
Saowanee Tangmanowutthikul +3 more
doaj +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt +9 more
wiley +1 more source
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT A comprehensive synthesis of the broad range of neurodevelopmental and psychiatric manifestations in NF1 is needed to identify knowledge gaps and future directions for NF1 research. In the following scoping review, we identify and summarize the scope of research that examines neurodevelopmental and psychiatric manifestations, both as ...
Meera Chopra +5 more
wiley +1 more source
Future Natural ProductsBackground and aims: The Valerianaceae comprises about 300 species of annual and perennial plants found worldwide. Several species are utilized for biological purposes, while others are consumed.
Mohammad Amin Manavi
doaj +1 more source
Posterior Reversible Encephalopathy Syndrome and Azathioprine [PDF]
, 2019 Posterior reversible encephalopathy syndrome (PRES) is a rare syndrome that presents with neurological manifestations, often associated with arterial hypertension.
Corte-Real, A, Vilas-Boas, S
core +2 more sources
Distinct Prescription Patterns Emerge Years Before ALS Diagnosis: A Nationwide Registry‐Based Study
Annals of Neurology, EarlyView.Objective The prodromal phase of amyotrophic lateral sclerosis (ALS) is poorly defined. We aimed to characterize prescription drug use patterns in the pre‐diagnostic period by analyzing nationwide prescription data to identify the earliest divergence between individuals who developed ALS and matched healthy controls.
Magne Haugland Solheim +6 more
wiley +1 more source
NGX-4010, a capsaicin 8% patch, for the treatment of painful HIV-associated distal sensory polyneuropathy: integrated analysis of two phase III, randomized, controlled trials [PDF]
, 2013 BACKGROUND HIV-associated distal sensory polyneuropathy (HIV-DSP) is the most frequently reported neurologic complication associated with HIV infection.
Brew, Bruce J +9 more
core +1 more source