Results 51 to 60 of about 53,577 (300)

1,2,3,-Triazole Anticonvulsant Drugs [PDF]

, 1986
Anticonvulsant compositions comprise as the active ingredient a compound . . .
Kadaba, Pankaja K.
core  

Neuropeptide receptors as potential antiepileptic drug targets : focus on the ghrelin axis [PDF]

, 2014
Epilepsy is a very serious neurological disorder which is often underrepresented. Around 50 million individuals worldwide have active epilepsy with recurrent seizures and in spite of the medical advances over the years, 30% of these patients remain as ...
Portelli, Jeanelle
core   +1 more source

Lactylation‐Mediated HER2 Stabilization Promotes Trastuzumab Resistance in Gastric Cancer

Advanced Science, EarlyView.
Warburg effect‐derived lactate drives HER2 lactylation and trastuzumab resistance. Mechanistically, AARS1‐mediated lactylation stabilizes HER2 by inhibiting USP11‐dependent degradation and concurrently promotes HER2‐EGFR interaction. Importantly, inhibiting HER2 lactylation resensitizes gastric cancer cells to trastuzumab.
Meng Qian, Tongguan Tian, Zhenxiang Wang, Huihui Sun, Ming Zong, Ying Chen, Jie Xiong, Ye Chen, Zhiqian Hu, Tianming Li, Yanping Xu, Shuchang Xu   +11 more
wiley   +1 more source

Initial Stay Time and Work‐Rest Scheduling During Consecutive Heavy‐Intensity Workdays in Hot Environments in Young and Older Males

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Introduction This study examined initial stay times (IST), defined as the duration of uninterrupted work before core temperature approaches recommended safety limits (38.0°C, ~1.0°C above baseline), and the efficacy of work‐rest cycles during repeated heavy work across consecutive workdays in young and older males.
Glen P. Kenny, Gil Bourgois, Sarah M. Taggart, Kelli E. McCormick, James J. McCormick, Leonidas G. Ioannou, Fergus K. O'Connor   +6 more
wiley   +1 more source

Osteocalcin in infants on anticonvulsant therapy

, 1986
Osteocalcin in infants on anticonvulsant ...
ZAMBONI, Giorgio, ANTONIAZZI, Franco, RUFFO G.   +2 more
core   +1 more source

Inhibitory Effect of Eslicarbazepine Acetate and S-Licarbazepine on Nav1.5 Channels

Frontiers in Pharmacology, 2020
Eslicarbazepine acetate (ESL) is a dibenzazepine anticonvulsant approved as adjunctive treatment for partial-onset epileptic seizures. Following first pass hydrolysis of ESL, S-licarbazepine (S-Lic) represents around 95% of circulating active metabolites.
Theresa K. Leslie, Lotte Brückner, Sangeeta Chawla, Sangeeta Chawla, William J. Brackenbury, William J. Brackenbury   +5 more
doaj   +1 more source

ADNP‐Related Helsmoortel–Van der Aa Syndrome: A Review of the Literature and Clinical Recommendations for Assessment and Monitoring

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT ADNP‐related Helsmoortel–Van der Aa syndrome (ADNP‐related HVDAS) is a single gene form of autism spectrum disorder (ASD) caused by pathogenic sequence variants in the activity‐dependent neuroprotective protein (ADNP) gene. In addition to ASD, ADNP‐related HVDAS is associated with a wide range of cognitive, behavioral, and physical health ...
Jarrett Fastman, Ana Kolevzon, Paige Siper, Tess Levy, Jeffrey M. Saland, Yitzchak Frank, Robert Rapaport, Kayla Kupietzky, William E. Bennett Jr, Bruce Gelb, Sandra Bedrosian Sermone, Alexander Kolevzon   +11 more
wiley   +1 more source

Sodium Valproate Induced Alopecia: A Case Series [PDF]

Journal of Clinical and Diagnostic Research, 2017
Drug induced alopecia may range from a barely detectable shedding to an irreversible baldness. Alopecia associated with valproate is a dose-dependent and reversible side effect.
Sereen Rose Thomson, Vinay Mamulpet, Shalini Adiga   +2 more
doaj   +1 more source

Triazoline Anticonvulsant Compounds and Compositions [PDF]

, 1987
Anticonvulsant compositions comprise as the active ingredient a compound . . .
Kadaba, Pankaja K.
core  

Possible Anticonvulsant lmidazolinones. Synthesis and Anticonvulsant Activity of 1N-(y' -Picolinoyl)-4-substituted- benzylidene-2-methyl/phenyl-5-imidazolinone

, 1991
Department of Chemistry, Saurashtra University, Rajkot-360 005 . Manuscript received 4 September 1990, accepted 23 April 1991 Possible Anticonvulsant lmidazolinones.
HANSA PAREKH, PARESH UPADHYAY, AJAY PANDYA   +2 more
core   +1 more source