Results 61 to 70 of about 88,387 (345)
Epilepsia Open, EarlyView., 2022 Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica +6 more
wiley +1 more source
A randomised trial of a medium-chain TAG diet as treatment for dogs with idiopathic epilepsy [PDF]
, 2015 Despite appropriate antiepileptic drug treatment, approximately one-third of humans and dogs with epilepsy continue experiencing seizures, emphasising the importance for new treatment strategies to improve the quality of life of people or dogs with ...
Brian Zanghi +17 more
core +3 more sources
European Psychiatry, 2022 Introduction The anticonvulsant m-Cl-BHM is promising for the pathogenetically directed thrapy does not cause negative effects. Objectives Investigation of the effect of m-Сl-BHM on “immunochemical homeostasis” in rats with experimental alcoholism ...
Т. Shushpanova +12 more
doaj +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Accurate classification of genomic variants is crucial to ensure correct diagnosis, genetic counseling, and clinical management of monogenic inherited disorders. Variant interpretation can be hindered in populations that are significantly underrepresented in large reference genomic databases, leading to genomic healthcare inequalities. Despite
Zantasha Khalid +16 more
wiley +1 more source
Epilepsia Open, EarlyView., 2022 Abstract Epilepsy is a heterogeneous disorder characterized by spontaneous seizures and behavioral comorbidities. The underlying mechanisms of seizures and epilepsy across various syndromes lead to diverse clinical presentation and features. Similarly, animal models of epilepsy arise from numerous dissimilar inciting events.
Melissa Barker‐Haliski +3 more
wiley +1 more source
Treating Epilepsy with Natural Products: Nonsense or Possibility?
Pharmaceuticals, 2023 Epilepsy is a neurological disease characterized by recurrent seizures that can lead to uncontrollable muscle twitching, changes in sensitivity to sensory perceptions, and disorders of consciousness.
Milan Malaník +5 more
doaj +1 more source
Animal models of cisplatin‐induced neuropathic pain
Animal Models and Experimental Medicine, EarlyView.This article illustrates the modeling process of a cisplatin‐induced neuropathic pain model in rats or mice. Multiple modeling tests are required for rats or mice before, during, and after modeling. The appropriate injection method, dose, and modeling method are selected, and multiple assays are chosen for evaluation and comparison.
Ningxin Li +9 more
wiley +1 more source
Differential expression of exosomal microRNAs in prefrontal cortices of schizophrenia and bipolar disorder patients [PDF]
, 2013 Exosomes are cellular secretory vesicles containing microRNAs (miRNAs). Once secreted, exosomes are able to attach to recipient cells and release miRNAs potentially modulating the function of the recipient cell.
Banigan, Meredith G. +11 more
core +4 more sources
Developmental Toxicity Study of DL-4-Hydroxy-4-Phenylhexanamide (DL-HEPB) in Rats
Life, 2023 Antiepileptic drugs affect embryonic development when administered during pregnancy, generating severe alterations, such as as cleft lip, spina bifida, heart abnormalities, or neuronal alterations.
José Melesio Cristóbal-Luna +5 more
doaj +1 more source
Optimal management of seizures associated with tuberous sclerosis complex: current and emerging options. [PDF]
, 2014 Seizures are clinically significant manifestations associated with 79%-90% of patients with tuberous sclerosis complex. Often occurring within the first year of life in the form of infantile spasms, seizures interfere with neuropsychiatric, social, and ...
Fallah, Aria, Wang, Shelly
core +2 more sources