Results 51 to 60 of about 267,421 (217)
The role of dissociation in ketamine’s antidepressant effects
Nature Communications, 2020 Ketamine produces immediate antidepressant effects and has inspired research into next-generation treatments. Ketamine also has short term dissociative effects, in which individuals report altered consciousness and perceptions of themselves and their ...
E. Ballard, C. Zarate
semanticscholar +1 more source
Antidepressant Medications and Weight Change: A Narrative Review
Obesity, 2020 Antidepressant medications are the first‐line treatment option for moderate to severe major depressive disorder. However, most antidepressants have numerous documented adverse events, including cardiometabolic effects and weight gain, which are major ...
H. Gill +13 more
semanticscholar +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2015 Background Recent studies have reported conflicting results on the association between selective serotonin reuptake inhibitors (SSRIs) and the risk of heart defects.
Shang Wang +5 more
doaj +1 more source
Frontiers in Psychiatry, 2011 Identifying biosignatures to assess the probability of response to an antidepressant for patients with Major Depressive Disorder (MDD) is critically needed. Functional connectivity MRI (fcMRI) offers the promise to provide such a measure.
F. Andrew eKozel +10 more
doaj +1 more source
An efficient multiple imputation algorithm for control-based and delta-adjusted pattern mixture models using SAS [PDF]
Statistics in Biopharmaceutical research 2016, 2016 In clinical trials, mixed effects models for repeated measures (MMRM) and pattern mixture models (PMM) are often used to analyze longitudinal continuous outcomes. We describe a simple missing data imputation algorithm for the MMRM that can be easily implemented in standard statistical software packages such as SAS PROC MI.
arxiv +1 more source
Antidepressants versus interpersonal psychotherapy in treating depression in HIV-positive patients.
South African Journal of Psychiatry, 2012 Aim. Despite the prevalence of HIV and AIDS in South Africa reaching pandemic proportions, very few studies have been published on co-morbid depression. This study at Chris Hani Baragwanath Hospital was conducted on a group of HIV-positive patients with ...
M Y H Moosa, F Y Jeenah
doaj +1 more source
Estimating Individualized Treatment Rules in Longitudinal Studies with Covariate-Driven Observation Times [PDF]
arXiv, 2022 The sequential treatment decisions made by physicians to treat chronic diseases are formalized in the statistical literature as dynamic treatment regimes. To date, methods for dynamic treatment regimes have been developed under the assumption that observation times, i.e., treatment and outcome monitoring times, are determined by study investigators ...
arxiv
Journal of Neuroscience, 1995 The influence of chronic electroconvulsive seizure (ECS) or antidepressant drug treatments on expression of brain-derived neurotrophic factor (BDNF) and its receptor, trkB, was examined by in situ hybridization and Northern blot. In frontal cortex, acute
M. Nibuya, S. Morinobu, R. Duman
semanticscholar +1 more source
Entity-based Claim Representation Improves Fact-Checking of Medical Content in Tweets [PDF]
arXiv, 2022 False medical information on social media poses harm to people's health. While the need for biomedical fact-checking has been recognized in recent years, user-generated medical content has received comparably little attention. At the same time, models for other text genres might not be reusable, because the claims they have been trained with are ...
arxiv
"When they say weed causes depression, but it's your fav antidepressant": Knowledge-aware Attention Framework for Relationship Extraction [PDF]
, 2020 With the increasing legalization of medical and recreational use of cannabis, more research is needed to understand the association between depression and consumer behavior related to cannabis consumption. Big social media data has potential to provide deeper insights about these associations to public health analysts.
arxiv +1 more source