Results 51 to 60 of about 298,427 (334)

Ecologically‐Valid Emotion Signatures Enhance Mood Disorder Diagnostics

open access: yesAdvanced Science, EarlyView.
This study identifies ecologically‐valid Divergent Emotional Functional Networks (DEFN), derived from dynamic functional connectivity during naturalistic movie watching. The DEFN reliably enhances diagnostic accuracy for mood disorders, including major depressive and bipolar disorders, demonstrating strong reproducibility across demographic factors and
Shuyue Xu   +6 more
wiley   +1 more source

Acneiform eruption associated with the use of vortioxetine

open access: yesPsychiatry and Clinical Psychopharmacology, 2019
Acneiform is used to describe eruptions that resemble acne vulgaris, but are not aetiologically similar. A number of drugs that can be responsible for acneiform eruptions exist.
Rukiye Ay, Ozgur Aytas
doaj   +1 more source

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

open access: yesAdvanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang   +12 more
wiley   +1 more source

The utility of PET imaging in depression

open access: yesFrontiers in Psychiatry
This educational review article aims to discuss growing evidence from PET studies in the diagnosis and treatment of depression. PET has been used in depression to explore the neurotransmitters involved, the alterations in neuroreceptors, non ...
Shashi B. Singh   +11 more
doaj   +1 more source

The pharmacological management of depression – Update 2017

open access: yesSouth African Family Practice, 2017
Depression affects nearly 350 million people worldwide. Local data indicates that approximately 17% of all South Africans will experience at least one episode of depression in their lifetime.
Elzbieta Osuch, Andre Marais
doaj   +1 more source

Behavioral and Developmental Changes in Brown Trout After Exposure to the Antidepressant Venlafaxine

open access: yesFrontiers in Environmental Science, 2021
During the last decades, depression has been diagnosed in increasing numbers, accompanied by rising prescription rates of antidepressants. Concomitantly, these pharmaceuticals are frequently detected in surface waters. Serotonin and noradrenalin reuptake
Michael Ziegler   +9 more
doaj   +1 more source

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

open access: yesAdvanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai   +12 more
wiley   +1 more source

Pharmacological mechanism of natural antidepressants: the role of epigenetic modifications

open access: yesFrontiers in Pharmacology
MDD is a complex mental illness shaped by the interplay between genetic vulnerability and environmental triggers. Its underlying pathophysiological processes are now understood to be influenced by epigenetic mechanisms.
Yitong Lu   +6 more
doaj   +1 more source

The Tuberculosis-Depression Syndemic and Evolution of Pharmaceutical Therapeutics: From Ancient Times to the Future

open access: yesFrontiers in Psychiatry, 2021
The interplay between tuberculosis and depression has been problematic since the humoralists. Over the centuries similarities in disease management have transpired.
Martie Van Der Walt, Karen H. Keddy
doaj   +1 more source

Risk of suicide during treatment with venlafaxine, italopram, fluoxetine, and dothiepin : retrospective cohort study [PDF]

open access: yes, 2006
Objective To compare the risk of suicide in adults usingthe antidepressant venlafaxine compared with citalopram, fluoxetine, and dothiepin. Design Retrospective cohort study. Setting UK General Practice Research Database. Participants 219 088 patients,
Andrews, Elizabeth   +5 more
core   +2 more sources

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