Management of bipolar depression
Indian Journal of Psychological Medicine, 2011 Patients with bipolar disorder spend more time in a depressed than manic state, even with individualized treatment. To date, bipolar depression is often misdiagnosed and ineffectively managed both for acute episodes and residual symptoms.
Jae Seung Chang, Kyooseob Ha
doaj +1 more source
Clinical Endocrinology, Volume 99, Issue 1, Page 79-91, July 2023., 2023 Abstract Objective As part of the update of the International Evidence‐Based Guidelines for the Assessment and Management of polycystic ovary syndrome (PCOS), a systematic review was performed to inform evidence‐based recommendations. Design Systematic review. Only randomised controlled trial were included. Patients Women with PCOS; the use of combined
Maria Forslund +9 more
wiley +1 more source
Smoking and antidepressants pharmacokinetics: a systematic review [PDF]
, 2017 Despite an increasingly recognized relationship between depression and smoking, little is known about how smoking influences antidepressant response and treatment outcomes.
Donato, H +3 more
core +1 more source
Cost-effectiveness analysis of pharmaceutical treatment options in the first-line management of major depressive disorder in Belgium [PDF]
, 2014 The objective of this study was to assess the cost effectiveness of commonly used antidepressants as first-line treatment of major depressive disorder (MDD) in Belgium.
Annemans, Lieven +5 more
core +2 more sources
Automatic summarization of MEDLINE citations for evidence-based medical treatment: A topic-oriented evaluation [PDF]
, 2008 As the number of electronic biomedical textual resources increases, it becomes harder for physicians to find useful answers at the point of care. Information retrieval applications provide access to databases; however, little research has been done on ...
Fiszman, Marcelo +3 more
core +1 more source
A Bayesian dose-response meta-analysis model: simulation study and application [PDF]
Vol 30, Issue 5, 2021, 2020 Dose-response models express the effect of different dose or exposure levels on a specific outcome. In meta-analysis, where aggregated-level data is available, dose-response evidence is synthesized using either one-stage or two-stage models in a frequentist setting. We propose a hierarchical dose-response model implemented in a Bayesian framework.
arxiv +1 more source
Insuficiência Hepática Aguda Induzida pela Trazodona e Diazepam [PDF]
, 2016 Most antidepressant agents have the potential to cause liver injury, even at therapeutic doses. Nevertheless, drug-induced liver injury (DILI) from antidepressant agents is a rare event. There is no way to prevent idiopathic DILI, but the severity of the
Barroso, E +5 more
core +1 more source
Designing AI for Trust and Collaboration in Time-Constrained Medical Decisions: A Sociotechnical Lens [PDF]
, 2021 Major depressive disorder is a debilitating disease affecting 264 million people worldwide. While many antidepressant medications are available, few clinical guidelines support choosing among them. Decision support tools (DSTs) embodying machine learning models may help improve the treatment selection process, but often fail in clinical practice due to
arxiv +1 more source
PET studies of the serotonin system in major depression and its treatment [PDF]
, 2014 The serotonin system has been implicated in major depression since the 1960s, mainly based on the serotonin enhancing properties of antidepressants.
Tiger, Mikael
core +1 more source
Successful Suicide in a Child: Depression-Related or Paroxetine-Induced? [PDF]
, 2017 Background: Children and adolescents are prone to develop psychiatric problems after stressful life events. These problems need appropriate treatment because of negative consequences like disease-related suicide.
Aghakhani, K +3 more
core +1 more source