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Antidepressant and antipsychotic agents

Naturwissenschaften, 1979
Numerous studies have been reviewed concerning the relationship of the catecholamines and indoleamines to depression and its treatment with antidepressant drugs. The profusion of data on the subject suggests the amines may be implicated in the disease, however no convincing hypothesis is available which unites the two.
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Is Agmatine an Endogenous Anxiolytic/Antidepressant Agent?

Annals of the New York Academy of Sciences, 2003
Abstract: Agmatine, an endogenous cationic amine, exerts a wide range of biologic effects, but its physiologic role is still to be determined. The aim of the present experiments was to investigate the role of agmatine in anxiety and depression. The forced swim test (FST) and the elevated plus maze (EPM) were used to determine the antidepressant and ...
Feyza Aricioglu, Hale Altunbas
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CYLOSERINE AS AN ANTIDEPRESSANT AGENT

American Journal of Psychiatry, 1959
Cycloserine appears to be a psychopharmacological agent in that 1. It reverses depressions to normal or hyperactive mood and at the same time causes subtle changes in behavior; 2. It may aggravate mental disorders; and 3. It seems to potentiate Marsilid.
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Fatal poisoning with the antidepressive agent opipramol

Forensic Science International, 1996
An ingestion of an unknown quantity ( < or = 3000 mg) of opipramol dihydrochloride in a suicide case is described. Quantitation of opipramol and its deshydroxyethyl metabolite was performed simultaneously after liquid-liquid extraction from alkalinized samples prior to HPLC analysis.
R. Aderjan, Gisela Skopp, Erich Miltner
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Antidepressant Agents in Short Bowel Syndrome

Clinical Therapeutics, 2014
This study aimed to determine whether short small intestine modifies antidepressant concentrations.The Css values and concentration-dose ratios (CDRs) of citalopram or escitalopram, administered orally or intravenously, were determined in patients with short bowel syndrome.Eight patients (6 males and 2 females) were included in the study.
E. Faye   +7 more
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Opioidergic Agents as Antidepressants: Rationale and Promise

CNS Drugs, 2018
Research concerning psychiatric issues relating to opioid drugs currently focuses primarily on their role in reinforcing addictive behaviors, given the recent proliferation of lethal abuse of illicit opiates in the United States and around the world. In contrast, this article will review the mechanism of action of opioids in affective disorders and the
Parnika P. Saxena   +2 more
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Quipazine, a new type of antidepressant agent

Psychopharmacologia, 1971
Quipazine, (2-(1-piperazinyl)quinoline), is comparable to the tricyclic antidepressants in many of its pharmacological effects. Common properties include the ability to antagonize reserpine and tetrabenazine sedation in mice and rats, to reverse reserpine hypothermia in rats and to inhibit selectively the mouse-killing behavior of rats.
Rodolfo Rodríguez, Efraín G. Pardo
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Antidepressant Augmentation With Anti-Inflammatory Agents

The Journal of Clinical Psychiatry, 2014
Antidepressant augmentation strategies are commonly employed to treat depressed patients who do not respond to antidepressant monotherapy. Neuroinflammatory mechanisms have been implicated in depression, and nonsteroidal anti-inflammatory drugs (NSAIDs) have been found effective in animal models of depression both in monotherapy and when used to ...
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Antidepressant Agents for the Treatment of Chronic Pain and Depression

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2007
Depression and painful somatic symptoms commonly occur together. Depression and chronic pain can have devastating effects on a patient's health, productivity, and overall quality of life. When moderate‐to‐severe pain exists, it can impair patient function while making treatment more difficult or resistant, with increased severity in depressive symptoms
Michael W. Jann, Julian H Slade
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Behavioural toxicity of antianxiety and antidepressant agents

Human Psychopharmacology: Clinical and Experimental, 1999
Standard measures of psychomotor speed and central nervous system arousal were used to assess the behavioural toxicity of several antianxiety and antidepressant agents. The results indicate that, for the agents evaluated, there is a wide variation in the effects on cognitive function.
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