Utility and Safety of Tolvaptan in Cirrhotic Patients with Hyponatremia: a Prospective Cohort Study
Annals of Hepatology, 2017 Introduction and aim: Hyponatremia is common in patients with decompensated cirrhosis and is associated with increased mortality. Tolvaptan, a vasopressor V2 receptor antagonist, can increase free water excretion, but its efficacy and safety in cirrhotic
Ji-Dong Jia +16 more
doaj +1 more source
Vasopressin regulates the growth of the biliary epithelium in polycystic liver disease [PDF]
, 2016 The neurohypophysial hormone arginine vasopressin (AVP) acts by three distinct receptor subtypes: V1a, V1b, and V2. In the liver, AVP is involved in ureogenesis, glycogenolysis, neoglucogenesis and regeneration. No data exist about the presence of AVP in
Alpini, Gianfranco +11 more
core +1 more source
The aquaretics in the treatment of hyponatremia
Italian Journal of Medicine, 2013 BACKGROUND Severe hyponatremia is the most common in-hospital electrolyte disorder and is a predictor of death among patients with chronic heart failure (CHF) and cirrhosis; it develops spontaneously or following diuretic therapy.
I. Portioli
doaj +1 more source
Hyponatremia : Special Considerations in Older Patients [PDF]
, 2014 Acknowledgments Roy L.
Clarke, Jennifer M +4 more
core +2 more sources
A systematic review and meta-analysis of thiazide-induced hyponatraemia: time to reconsider electrolyte monitoring regimens after thiazide initiation? [PDF]
, 2014 Aims: Hyponatraemia is one of the major adverse effects of thiazide and thiazide-like diuretics and the leading cause of drug-induced hyponatraemia requiring hospital admission.
Barber, Jennifer +9 more
core +4 more sources
Altered agonist sensitivity of a mutant V2 receptor suggests a novel therapeutic strategy for nephrogenic diabetes insipidus. [PDF]
, 2014 Loss of function mutations of the type 2 vasopressin receptor (V2R) in kidney can lead to nephrogenic diabetes insipidus (NDI). We studied a previously described, but uncharacterized mutation of V2R (N321K missense mutation) of an NDI patient.
Balla, András +5 more
core +1 more source
Therapeutic Advances in Endocrinology and Metabolism, 2012 Hyponatremia is the most frequent electrolyte disorder and the syndrome of inappropriate antidiuretic hormone secretion (SIADH) accounts for approximately one-third of all cases.
Peter Gross
doaj +1 more source
Hyponatremia revisited: Translating physiology to practice [PDF]
, 2008 The complexity of hyponatremia as a clinical problem is likely caused by the opposite scenarios that accompany this electrolyte disorder regarding pathophysiology (depletional versus dilutional hyponatremia, high versus low vasopressin levels) and ...
Adrogue HJ +62 more
core +2 more sources
Parathyroid localization [PDF]
, 1986 Twenty-nine consecutive patients with suspected primary hyperparathyroidism were examined preoperatively using ultrasound, sonographically guided fine needle aspiration, and aspirate immunostaining for PTH.
Borisch, B. +7 more
core +1 more source
Interventions for chronic non-hypovolaemic hypotonic hyponatraemia (Review) [PDF]
, 2018 Background : Chronic (present > 48 hours) non-hypovolaemic hyponatraemia occurs frequently, can be caused by various conditions, and is associated with shorter survival and longer hospital stays.
Craig, Jonathan C +5 more
core +2 more sources