Efficacy and safety of using antifibrinolytic agents in spine surgery: a meta-analysis. [PDF]
PLoS ONE, 2013 PURPOSE: Spine surgery, particularly reconstructive surgery, can be associated with significant blood loss, and blood transfusion. Antifibrinolytic agents are used routinely to reduce bleeding in cardiac, orthopaedic, and hepatic surgery.
Chaoqun Yuan, Hailong Zhang, Shisheng He
doaj +4 more sources
Efficacy and safety of antifibrinolytic agents in spinal surgery: a network meta-analysis [PDF]
Chinese Medical Journal, 2019 . Background:. Significant blood loss is still one of the most frequent complications in spinal surgery, which often necessitates blood transfusion. Massive perioperative blood loss and blood transfusion can create additional risks. Aprotinin, tranexamic
Lei Yuan +7 more
doaj +3 more sources
Efficacy and Safety of Antifibrinolytic Agents in Reducing Perioperative Blood Loss and Transfusion Requirements in Scoliosis Surgery: A Systematic Review and Meta-Analysis. [PDF]
PLoS ONE, 2015 BackgroundRoutine use of antifibrinolytic agents in spine surgery is still an issue of debate.ObjectiveTo gather scientific evidence for the efficacy and safety of antifibrinolytic agents including aprotinin, tranexamic acid (TXA) and epsilon ...
Meng Wang +2 more
doaj +3 more sources
Antifibrinolytic agents in traumatic haemorrhage. [PDF]
PLoS Medicine, 2005 Tim Coats +3 more
doaj +6 more sources
Antifibrinolytic agents for the prevention of postpartum hemorrhage
Thrombosis Update, 2021 Acute obstetric coagulopathy secondary to postpartum hemorrhage (PPH) is associated with poor outcome. There is evidence that Tranexamic Acid (TA), an antifibrinolytic drug, is an efficient tool of patient blood management in association with uterotonics
Anne-Sophie Bouthors +3 more
doaj +2 more sources
Perioperative management of severe factor VII deficiency: a single-center experience in China [PDF]
Frontiers in MedicineIntroductionInherited factor VII (FVII) deficiency is a rare autosomal recessive disorder whose clinical phenotypes are highly variable. Many studies have observed the absence of a clear-cut and consistent correlation between bleeding symptoms and FVII ...
Chao Zhu +5 more
doaj +2 more sources
Salts of S-(+)-Ibuprofen Formed via Its Reaction with the Antifibrinolytic Agents Aminocaproic Acid and Tranexamic Acid: Synthesis and Characterization [PDF]
Crystals, 2023 The paucity of multi-component compounds containing the non-steroidal anti-inflammatory drug (NSAID) S-(+)-ibuprofen (S-IBU) in combination with other drugs prompted the present study, which describes 1:1 salts of this active pharmaceutical ingredient ...
Hannah M. Frösler +3 more
doaj +2 more sources
Do Antifibrinolytic Agents Reduce the Risk of Blood Transfusion in Children Undergoing Spinal Fusion?: A Propensity Score-matched Comparison Using a National Database. [PDF]
Spine (Phila Pa 1976), 2020 Eisler LD +4 more
europepmc +3 more sources
Predictors of Hematoma Enlargement in Patients with Spontaneous Intracerebral Hemorrhage Treated with Rapid Administration of Antifibrinolytic Agents and Strict Conservative Management. [PDF]
Korean J Neurotrauma, 2019 Kim CH +5 more
europepmc +3 more sources
Antifibrinolytic agents for reducing blood loss in scoliosis surgery in children. [PDF]
Cochrane Database Syst Rev, 2016 McNicol ED +4 more
europepmc +3 more sources