Antithrombotic therapy in patients receiving saphenous vein coronary artery bypass grafts: a protocol for a systematic review and network meta-analysis. [PDF]
INTRODUCTION: The current evidence for the prevention of saphenous vein graft failure (SVGF) after coronary artery bypass graft (CABG) surgery consists of direct head-to-head comparison of treatments (including placebo) in randomised-controlled trials ...
Solo, K+8 more
core +3 more sources
Current concepts of the management of dental extractions for patients taking warfarin [PDF]
The document attached has been archived with permission from the Australian Dental Association. An external link to the publisher’s copy is included.Background: Controversy has surrounded the correct management of patients therapeutically anticoagulated ...
Akbarian M.+45 more
core +1 more source
Acquired angioedema (AAE) is characterized by acquired deficiency of C1 inhibitor (C1-INH), hyperactivation of the classical pathway of human complement and angioedema symptoms mediated by bradykinin released by inappropriate activation of the contact ...
Cicardi Marco, Zanichelli Andrea
doaj +1 more source
Bench-to-bedside review: the role of activated protein C in maintaining endothelial tight junction function and its relationship to organ injury. [PDF]
Activated protein C (APC) has emerged as a novel therapeutic agent for use in selected patients with severe sepsis, even though the mechanism of its benefit is not well established.
Looney, Mark R, Matthay, Michael A
core +2 more sources
MANAGEMENT OF THE HAEMOPHILIC PATIENT IN DENTISTRY AND CERVICOFACIAL SURGERY
In patients with haemophilia, any oral surgery carries the risk of prolonged and excessive bleeding. Close collaboration between haematologists and oral surgeons is necessary to prevent excessive bleeding.
Lidia Cureniuc+11 more
doaj
Antifibrinolytics in cardiac surgery
Cardiac surgery exerts a significant strain on the blood bank services and is a model example in which a multi-modal blood-conservation strategy is recommended.
Achal Dhir
doaj +1 more source
Background: For adults undergoing complex, multilevel spinal surgery, tranexamic acid (TXA) is an antifibrinolytic agent used to reduce blood loss. The optimal dosing of intravenous TXA remains unclear.
Roman Rahmani+4 more
doaj +1 more source
Clinically Significant Thromboembolic Disease in Adult Spinal Deformity Surgery: Incidence and Risk Factors in 737 Patients. [PDF]
Study Design:Retrospective cohort study. Objectives:Describe the rate and risk factors for venous thromboembolic events (VTEs; defined as deep venous thrombosis [DVT] and/or pulmonary embolism [PE]) in adult spinal deformity (ASD) surgery.
Bess, Shay+14 more
core +1 more source
Abstract Postpartum hemorrhage (PPH) remains the leading cause of maternal mortality globally. This global survey was conducted to identify any disparities in the causes, prevalence, treatment, and mortality burden of PPH, with the aim of proposing relevant recommendations to bridge these disparities and ultimately reduce the global maternal mortality ...
Akaninyene E. Ubom+8 more
wiley +1 more source
The use of fibrinogen concentrate for the management of trauma-related bleeding. A systematic review and meta-analysis [PDF]
Haemorrhage following injury is associated with significant morbidity and mortality. The role of fibrinogen concentrate in trauma-induced coagulopathy has been the object of intense research in the last 10 years and has been systematically analysed in ...
Franchini, Massimo+6 more
core +1 more source