Results 61 to 70 of about 7,826 (216)
Aplastic anemia is a hematological disorder characterized by pancytopenia. This case report presents a young patient with untreated periodontitis associated with hematological disorders, and cyclosporine therapy.
Ivan Puhar +4 more
doaj +1 more source
Background Tranexamic acid (TXA) is an antifibrinolytic drug that blocks lysine-binding sites on the profibrinolytic enzyme plasminogen. Aortic diseases with chronic consumption coagulopathy may lead to disseminated intravascular coagulation (DIC) and ...
Naruko Suzuki +10 more
doaj +1 more source
Inhibitors in Patients with Congenital Bleeding Disorders Other Than Hemophilia [PDF]
The most worrying complication of replacement therapy for severe hemophilia A and B is currently the occurrence of inhibitory alloantibodies against infused factor VIII and factor IX, respectively.
Franchini, Massimo +6 more
core +1 more source
Early TXA administration (≤ 3 h) in concurrent hemorrhage and TBI was significantly associated with a 22% reduction in mortality at 7 days. TXA treatment was also associated with a significant 29% lower odds of organ failure and non‐significant 11% odds of good neurologic recovery.
Julia M. Dixon +13 more
wiley +1 more source
Postoperative tonsil/adenoidectomy bleeding management in patients with diagnosed bleeding disorders
Objective Tonsil/adenoidectomy (T/A) is a commonly performed procedure with an average post‐tonsillectomy bleed (PTB) rate between 3 and 5%. Patients with bleeding disorders (BDs) are believed to have an increased risk of PTB.
Kavya Pai +3 more
doaj +1 more source
Lytic and mechanical stability of clots composed of fibrin and blood vessel wall components. [PDF]
Background Proteases expressed in atherosclerotic plaque lesions generate collagen fragments, release glycosaminoglycans (chondroitin sulfate [CS] and dermatan sulfate [DS]) and expose extracellular matrix (ECM) proteins (e.g.
Bóta, Attila +7 more
core +1 more source
Abstract Background Liver transplantation is the only curative treatment for end‐stage liver disease, yet perioperative management is complex and high‐risk. Variations in anesthetic practices may influence outcomes, but benchmarks are scant. This study characterizes liver transplant anesthesia practices in Canada, Australia, and New Zealand to identify
Elizabeth van Rooy +3 more
wiley +1 more source
An update on the management of anticoagulated patients programmed for dental extractions and surgery [PDF]
Oral anticoagulants (OACs) antagonizing vitamin K - fundamentally sodium warfarin and acenocoumarol - are widely used for preventing arterial thromboembolism in patients with atrial fibrillation and/or heart valve prostheses, and for the treatment and ...
Gavaldá Esteve, Carmen +4 more
core
Targeting Melasma: Innovations in Pigment Deposition and Photoaging in Cosmetic Dermatology
ABSTRACT Background Melasma is a chronic, relapsing hyperpigmentation disorder driven by complex interactions among genetic predisposition, hormonal fluctuations, UV exposure, oxidative stress, inflammation, and photoaging. Its psychosocial impact is substantial, especially among women with darker skin types, and treatment remains challenging due to ...
Ting Liao +4 more
wiley +1 more source
INTRODUÇÃO: O ácido épsilon aminocapróico é um antifibrinolítico usado em cirurgia cardiovascular a fim de inibir a fibrinólise e reduzir o sangramento após circulação extracorpórea (CEC).
Ricardo Adala Benfatti +5 more
doaj +1 more source

