Results 1 to 10 of about 437,849 (236)
Metabolites, 2020 We reviewed the licensed antifungal drugs and summarized their mechanisms of action, pharmacological profiles, and susceptibility to specific fungi.
Jiří Houšť +2 more
semanticscholar +5 more sources
Frontiers in Cellular and Infection Microbiology, 2021 In many ways, fungal diseases are forgotten or neglected. Given the significantly lower frequency compared to similar bacterial etiologies across the spectrum of infectious syndromes, it makes sense that anti-bacterial agents have seen the bulk of development in recent decades.
Todd Patrick McCarty +2 more
openaire +3 more sources
In vitro activities of Traganum nudatum and Mentha pulegium extracts combined with amphotericin B against Candida albicans in production of hydrolytic enzymes [PDF]
Current Medical Mycology, 2020 Background and Purpose: Candida albicans is an important microorganism in the normal flora of a healthy subject; however, it has an expedient pathogenic character that induces hydrolytic virulence.
Ikram Tefiani +2 more
doaj +1 more source
Molecular mechanisms governing antifungal drug resistance
npj antimicrobials and resistance, 2023 Fungal pathogens are a severe public health problem. The leading causative agents of systemic fungal infections include species from the Candida, Cryptococcus, and Aspergillus genera.
Yunjin Lee, Nicole Robbins, L. Cowen
semanticscholar +1 more source
Tackling the emerging threat of antifungal resistance to human health
Nature Reviews Microbiology, 2022 Invasive fungal infections pose an important threat to public health and are an under-recognized component of antimicrobial resistance, an emerging crisis worldwide.
M. Fisher +19 more
semanticscholar +1 more source
Chitosan and Chitosan Nanoparticles: Parameters Enhancing Antifungal Activity
Molecules, 2023 Chitosan (CS), a biopolymer derived from chitin, is known for strong antifungal activity while being biodegradable, biocompatible, and non-toxic. Because of its characteristic it has been widely used in control of fungal pathogens. Antifungal activity of
P. Poznański, A. Hameed, W. Orczyk
semanticscholar +1 more source
The Antifungal Pipeline: Fosmanogepix, Ibrexafungerp, Olorofim, Opelconazole, and Rezafungin
Drugs, 2021 The epidemiology of invasive fungal infections is changing, with new populations at risk and the emergence of resistance caused by the selective pressure from increased usage of antifungal agents in prophylaxis, empiric therapy, and agriculture.
M. Hoenigl +11 more
semanticscholar +1 more source
Journal of Fungi, 2021 Fungal infections represent an increasing public health crisis [...]
openaire +3 more sources
Emerging Antifungal Targets and Strategies
International Journal of Molecular Sciences, 2022 Despite abundant research in the field of antifungal drug discovery, fungal infections remain a significant healthcare burden. There is an emerging need for the development of novel antifungals since those currently available are limited and do not ...
Marija Ivanov +2 more
semanticscholar +1 more source
Proceedings of the National Academy of Sciences, 2007 Fungi are increasingly identified as major pathogens in bloodstream infections, often involving indwelling devices. Materials with antifungal properties may provide an important deterrent to these infections. Here we describe amphogel, a dextran-based hydrogel into which amphotericin B is adsorbed.
Zumbuehl, Andréas +10 more
openaire +4 more sources