Results 41 to 50 of about 440,532 (310)

Vertebrate Hosts as Islands: Dynamics of Selection, Immigration, Loss, Persistence, and Potential Function of Bacteria on Salamander Skin. [PDF]

, 2016
Skin bacterial communities can protect amphibians from a fungal pathogen; however, little is known about how these communities are maintained. We used a neutral model of community ecology to identify bacteria that are maintained on salamanders by ...
Harris, Reid N, Knight, Rob, Loudon, Andrew H, McKenzie, Valerie J, Parfrey, Laura Wegener, Schmidt, Thomas M, Van Treuren, William, Venkataraman, Arvind, Woodhams, Douglas C   +8 more
core   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Antinomic natural self-protection mechanism in long-lasting woods: a case study with three tropical species from French Guiana [PDF]

, 2009
We demonstrate in this work through 3 examples that Amazonian trees may specialize longlasting woods by means of at least to different approaches. Wallaba impregnates its wood with large amounts of weakly antifungal compounds acting in synergy, while ...
Amusant, Nadine, Beauchêne, Jacques, Eparvier, Véronique, Espindola, Laila S., Herbette, Gaëtan, Rodrigues, Alice M.S., Royer, Mariana, Stien, Didier, Thibaut, Anne, Thibaut, Bernard   +9 more
core  

An investigation into the pathogenesis of vulvo-vaginal candidosis [PDF]

, 2001
OBJECTIVE: To monitor yeasts isolated from women during and between episodes of recurrent vulvo-vaginal candidosis (VVC) to determine whether vaginal relapse or re-infection occurred. METHODS:Women presenting at the genitourinary medicine clinic with
Ashbee, H.R., Barton, R.C., El-Din, S.S., Evans, E.G.V., Reynolds, M.T.   +4 more
core   +2 more sources

Shaping Ti3C2 MXene Nanospheres for Precision Near‐Infrared Photothermal Therapy

Advanced Functional Materials, EarlyView.
In this study, we report producing spherical MXenes via fs laser fragmentation of Ti3C2 flakes in liquid medium. The nanoparticles demonstrated pronounced light absorption and high photothermal conversion efficiencies of 68% and 63% under heating with NIR‐I and NIR‐II lasers, respectively.
Julia S. Babkova, Ivan V. Zelepukin, Konstantin G. Shevchenko, Gleb V. Tikhonowski, Lyubov V. Gorelik, Anton A. Popov, Anna S. Sogomonyan, Alina Yu. Kapitannikova, Ivan S. Kazantsev, Dmitry V. Dyubo, Daria A. Panova, Daniil I. Tselikov, Anton A. Minnekhanov, Aziz B. Mirkasymov, Georgy A. Ermolaev, Alexander V. Syuy, Gleb I. Tselikov, Aleksey V. Arsenin, Andrei V. Kabashin, Kostya S. Novoselov, Sergey M. Deyev, Valentyn S. Volkov   +21 more
wiley   +1 more source

Cardiac‐Derived ECM Microspheres for Enhanced hiPSC‐CMs Maturation

Advanced Functional Materials, EarlyView.
Cardiac extracellular matrix microspheres derived from decellularized porcine heart provide a biomimetic 3D microenvironment for human induced pluripotent stem cell–derived cardiomyocytes (hiPSC‐CMs). This platform supports short‐ and long‐term culture, enhances structural organization, and promotes electrophysiological and functional maturation of ...
Jiazhu Xu, Joel Aboagye, Marcella Edwards, Nick Rogozinski, Yufeng Wen, Angello Huerta Gomez, Zui Pan, Ge Zhang, Huaxiao Yang, Yi Hong   +9 more
wiley   +1 more source

Physiological Analysis (Monitoring of Germinal and Biometric Parameters) of Abelmoschus esculentus L. Seeds under the Effect of 100 mM and 150 mM NaCl

Biology and Life Sciences Forum
Abelmoschus esculentus L. is a plant of legume origin; it is used in several areas of nutrition, industry and medicine. This study was proposed in order to understand the adaptation mechanisms of the seeds of this species under the effect of NaCl ...
Khedidja Dahli, Houria Medjdoub
doaj   +1 more source

Fatty Acids and Oxylipins as Antifungal and Anti-Mycotoxin Agents in Food: A Review

Toxins, 2021
Fungal contamination of food, especially by mycotoxigenic fungi, not only reduces the quality of the food, but can also cause serious diseases, thus posing a major food safety challenge to humans.
Mei Qiu, Yaling Wang, Lijun Sun, Qi Deng, Jian Zhao   +4 more
doaj   +1 more source

Gaining insights from Candida biofilm heterogeneity: one size does not fit all [PDF]

, 2018
Despite their clinical significance and substantial human health burden, fungal infections remain relatively under-appreciated. The widespread overuse of antibiotics and the increasing requirement for indwelling medical devices provides an opportunistic ...
Delaney, Christopher, Kean, Ryan, McLean, William, Metcalfe, Rebecca, Rajendran, Ranjith, Ramage, Gordon, Sherry, Leighann, Thomas, Rachael, Williams, Craig   +8 more
core   +4 more sources