Virulence and biofilms as promising targets in developing antipathogenic drugs against candidiasis
Candida albicans has remained the main etiological agent of candidiasis, challenges clinicians with high mortality and morbidity. The emergence of resistance to antifungal drugs, toxicity and lower efficacy have all contributed to an urgent need to ...
Mohd Sajjad Ahmad Khan +5 more
doaj +1 more source
Species Distribution and in Vitro Antifungal Susceptibility of Oral Yeast Isolates from Tanzanian HIV-Infected Patients With Primary and Recurrent Oropharyngeal Candidiasis. [PDF]
\ud In Tanzania, little is known on the species distribution and antifungal susceptibility profiles of yeast isolates from HIV-infected patients with primary and recurrent oropharyngeal candidiasis.
Rijs Antonius JMM +51 more
core +2 more sources
The Lysine Deacetylase RpdA Is Essential for Virulence in Aspergillus fumigatus
Current suboptimal treatment options of invasive fungal infections and emerging resistance of the corresponding pathogens urge the need for alternative therapy strategies and require the identification of novel antifungal targets.
Ingo Bauer +9 more
doaj +1 more source
Immunotherapy of invasive fungal infection in hematopoietic stem cell transplant recipients [PDF]
Despite the availability of new antifungal compounds, invasive fungal infection remains a significant cause of morbidity and mortality in children and adults undergoing allogeneic hematopoietic stem cell transplantation (HSCT). Allogeneic HSCT recipients
Lehrnbecher, Thomas +7 more
core +1 more source
Trichophyton mentagrophytes and Candida albicans Antifungal Activity of Palanjau (Pentaspadon metleyi) Wood Extractives Pelanjau wood (P. motleyi) extractives traditionally used as medicine for skin infection such as scabies (tinea) and rash caused by ...
Fathul Yusro +2 more
doaj +1 more source
Bio-fabrication of Zinc Oxide nanoparticles to rescue Mung Bean against Cercospora leaf spot disease
Plant disease management using nanotechnology is evolving continuously across the world. The purpose of this study was to determine the effect of different concentrations of green synthesized zinc oxide nanoparticles (ZnO NPs) using Trachyspermum ammi ...
Hamza Rafiq +11 more
doaj +1 more source
ANTIFUNGAL ASSESSMENTS, CHEMOGENOMIC AND TRANSCRIPTOMIC ANALYSES, AND STRUCTURE-ACTIVITY RELATIONSHIPS OF BIOACTIVE AURONE COMPOUNDS [PDF]
Candida spp. as commensal colonizers of mucocutaneous surfaces in humans are the major fungal cause of bloodstream infections, resulting in 50,000 deaths every year.
Alqahtani, Fatmah Mohammed
core
Do farnesol and tyrosol production in Candidozyma auris biofilms reflect virulence potential?
Candidozyma auris is associated with nosocomial outbreaks presenting high resistance rates to antifungal. Since its emergence in 2009, research has been carried out on the underlying quorum sensing molecules (QSMs), such as farnesol (Far) and tyrosol ...
Murilo Moreira dos Santos +3 more
doaj +1 more source
Fungal biofilm resistance [PDF]
Fungal biofilm infections have become increasingly recognised as a significant clinical problem. One of the major reasons behind this is the impact that these have upon treatment, as antifungal therapy often fails and surgical intervention is required ...
Ramage, Gordon +7 more
core +1 more source
Preformed antifungal compounds in strawberry fruit and flower tissues [PDF]
Antifungal activity against the pathogen, Botrytis cinerea, and a bioassay organism, Cladosporium cladosporioides, declined with advancing strawberry fruit maturity as shown by thin layer chromatography (TLC) bioassays.
Joyce, Daryl C. +15 more
core +1 more source

