Biofilm-forming capability of highly virulent, multidrug-resistant Candida auris [PDF]
, 2017 The emerging multidrug-resistant yeast pathogen Candida auris has attracted considerable attention as a source of healthcare–associated infections. We report that this highly virulent yeast has the capacity to form antifungal resistant biofilms sensitive
Borman, Andrew +6 more
core +4 more sources
Intensive care unit-related fluconazole use in Spain and Germany: patient characteristics and outcomes of a prospective multicenter longitudinal observational study [PDF]
, 2013 Background: Candida spp. are a frequent cause of nosocomial bloodstream infections worldwide. Objective: To evaluate the use patterns and outcomes associated with intravenous (IV) fluconazole therapy in intensive care units in Spain and Germany ...
Ballus, Jose +7 more
core +1 more source
Effect of Perillaldehyde on Prophylaxis and Treatment of Vaginal Candidiasis in a Murine Model
Frontiers in Microbiology, 2019 Vulvovaginal candidiasis is a common fungal infection afflicting women which is primarily caused by the yeast Candida albicans (C. albicans). It is imperative to introduce new drug classes to counter this threat due to the continuous emergence of drug ...
Su Qu +12 more
doaj +1 more source
Fungicidal activity plus reservoir effect allow short treatment courses with terbinafine in tinea pedis [PDF]
, 2008 Terbinafine, a synthetic allylamine, exerts fungicidal activity against dermatophytes, the causative pathogens of tinea pedis. As proven in numerous clinical trials, tinea pedis can be effectively and safely treated by topical terbinafine.
Korting, Hans Christian +2 more
core +1 more source
Molecular Detection of Azole-Resistant Aspergillus fumigatus in Clinical Samples
Frontiers in Microbiology, 2018 Aspergillus diseases are often caused by Aspergillus fumigatus. Azoles are the mainstay of therapy, but the management of aspergillosis is hampered by the emergence of azole resistance.
Jochem B. Buil +7 more
doaj +1 more source
Do farnesol and tyrosol production in Candidozyma auris biofilms reflect virulence potential?
VirulenceCandidozyma auris is associated with nosocomial outbreaks presenting high resistance rates to antifungal. Since its emergence in 2009, research has been carried out on the underlying quorum sensing molecules (QSMs), such as farnesol (Far) and tyrosol ...
Murilo Moreira dos Santos +3 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Due to the increasing prevalence of life-threatening bacterial, fungal and viral infections and the ability of these human pathogens to develop resistance to current treatment strategies, there is a great need to find and develop new compunds to combat ...
Diana Stan +8 more
doaj +1 more source
In vitro biofilms and antifungal susceptibility of dermatophyte and non-dermatophyte moulds involved in foot mycosis [PDF]
, 2017 Tinea pedis and onychomycosis are among the commonest fungal diseases in the world. Dermatophytes and, less frequently, non-dermatophyte moulds are aetiological agents of foot mycosis and are capable of forming biofilms.
Bougnoux, Marie Élisabeth +5 more
core +1 more source
Synthesis and antimicrobial evaluation of some 1-(4-arylthiazol-2-yl)-1′-(aryl/heteroaryl)-3,3′-dimethyl-[4,5′-bi-1H-pyrazol]-5-ols [PDF]
Journal of the Serbian Chemical Society, 2017 A series of sixteen 1-(4-arylthiazol-2-yl)-1′-(aryl/heteroaryl)-3,3′-dimethyl-[ 4,5′-bi-1H-pyrazol]-5-ols (7a–p) was synthesized starting from dehydroacetic acid (DHA, 1) via the stepwise formation of thiosemicarbazone (2), 3-(1-(2-(4-arylthiazol-2-yl ...
Mor Satbir +3 more
doaj +1 more source
Digital Chinese MedicineObjective: To evaluate the in vitro anti-diabetic effects of Bryonia dioica roots extracts, including water-acetone extracts and their ethyl acetate and butanol fractions, and chloroform-methanol extracts. Methods: The total phenolic, flavonoid, flavonol,
Fekhikher Zohra +11 more
doaj +1 more source