Antifungal Resistance and the Role of New Therapeutic Agents
Current Infectious Disease Reports, 2022 Advances in health care over time have led to an evolution in the epidemiology of invasive fungal infections. There is an increasing concern for antifungal resistance and emergence of less common fungal species for which optimal therapies are not well ...
Ashley Logan, A. Wolfe, J. Williamson
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Intensive care unit-related fluconazole use in Spain and Germany: patient characteristics and outcomes of a prospective multicenter longitudinal observational study [PDF]
, 2013 Background: Candida spp. are a frequent cause of nosocomial bloodstream infections worldwide. Objective: To evaluate the use patterns and outcomes associated with intravenous (IV) fluconazole therapy in intensive care units in Spain and Germany ...
Ballus, Jose +7 more
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Azole Antifungal Resistance in Candida albicans and Emerging Non-albicans Candida Species
Frontiers in Microbiology, 2017 Within the limited antifungal armamentarium, the azole antifungals are the most frequent class used to treat Candida infections. Azole antifungals such as fluconazole are often preferred treatment for many Candida infections as they are inexpensive ...
D. Sanglard +7 more
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The Lysine Deacetylase RpdA Is Essential for Virulence in Aspergillus fumigatus
Frontiers in Microbiology, 2019 Current suboptimal treatment options of invasive fungal infections and emerging resistance of the corresponding pathogens urge the need for alternative therapy strategies and require the identification of novel antifungal targets.
Ingo Bauer +9 more
doaj +1 more source
Fungicidal activity plus reservoir effect allow short treatment courses with terbinafine in tinea pedis [PDF]
, 2008 Terbinafine, a synthetic allylamine, exerts fungicidal activity against dermatophytes, the causative pathogens of tinea pedis. As proven in numerous clinical trials, tinea pedis can be effectively and safely treated by topical terbinafine.
Korting, Hans Christian +2 more
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Candida auris Isolates Resistant to Three Classes of Antifungal Medications — New York, 2019
MMWR. Morbidity and mortality weekly report, 2020 Candida auris is a globally emerging yeast that causes outbreaks in health care settings and is often resistant to one or more classes of antifungal medications (1). Cases of C. auris with resistance to all three classes of commonly prescribed antifungal
B. Ostrowsky +17 more
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Activity and Mechanism of Action of Antifungal Peptides from Microorganisms: A Review
Molecules, 2021 Harmful fungi in nature not only cause diseases in plants, but also fungal infection and poisoning when people and animals eat food derived from crops contaminated with them.
Tianxi Li +6 more
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Jurnal Ilmu Kehutanan, 2013 Trichophyton mentagrophytes and Candida albicans Antifungal Activity of Palanjau (Pentaspadon metleyi) Wood Extractives Pelanjau wood (P. motleyi) extractives traditionally used as medicine for skin infection such as scabies (tinea) and rash caused by ...
Fathul Yusro +2 more
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Global Antifungal Profile Optimization of Chlorophenyl Derivatives against Botrytis cinerea and Colletotrichum gloeosporioides [PDF]
, 2009 Twenty-two aromatic derivatives bearing a chlorine atom and a different chain in the para or meta position were prepared and evaluated for their in vitro antifungal activity against the phytopathogenic fungi Botrytis cinerea and Colletotrichum ...
Aleu J. +31 more
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Advances in Antifungal Drug Development: An Up-To-Date Mini Review
Pharmaceuticals, 2021 The utility of clinically available antifungals is limited by their narrow spectrum of activity, high toxicity, and emerging resistance. Antifungal drug discovery has always been a challenging area, since fungi and their human host are eukaryotes, making
Ghada Bouz, M. Doležal
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