Results 151 to 160 of about 134,309 (205)
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Pharmacokinetics of Antifungal Agents
Peritoneal Dialysis International, 1993The authors have evaluated the pharmacokinetics of four antifungal agents used in the therapy of fungal peritonitis. Amphotericin B (Amph B) poorly diffuses from blood into peritoneal fluid, which Intraperitoneal administration induces severe abdominal pain.
A Fabris
exaly +3 more sources
Medical Journal of Australia, 2007
The four main classes of antifungal drugs are the polyenes, azoles, allylamines and echinocandins. Clinically useful "older" agents include topical azole formulations (for superficial yeast and dermatophyte infections), first-generation triazoles (fluconazole and itraconazole, for a range of superficial and invasive fungal infections), amphotericin B ...
Sharon C A, Chen, Tania C, Sorrell
openaire +2 more sources
The four main classes of antifungal drugs are the polyenes, azoles, allylamines and echinocandins. Clinically useful "older" agents include topical azole formulations (for superficial yeast and dermatophyte infections), first-generation triazoles (fluconazole and itraconazole, for a range of superficial and invasive fungal infections), amphotericin B ...
Sharon C A, Chen, Tania C, Sorrell
openaire +2 more sources
Seminars in Respiratory Infections, 2002
Treatment of fungal infections is an area of increasing concern. This is because of the complexity of underlying illness in affected patients as well as the limited number of antifungal agents available for use. Current strategies focus on prevention of these infections in patients at high risk; however, this has the potential to lead to the emergence ...
Irene, Lu +2 more
openaire +4 more sources
Treatment of fungal infections is an area of increasing concern. This is because of the complexity of underlying illness in affected patients as well as the limited number of antifungal agents available for use. Current strategies focus on prevention of these infections in patients at high risk; however, this has the potential to lead to the emergence ...
Irene, Lu +2 more
openaire +4 more sources
Science, 1961
From the soil of the San Joaquin Valley a fungus has been isolated, an extract of which inhibits the growth of Coccidioides immitis on Sabouraud's medium. An acute toxicity study in mice indicates a certain tolerance of the extract. Tentative identification indicates that the fungus is a penicillium.
M C, EGEBERG, A F, ELCONIN, R O, EGEBERG
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From the soil of the San Joaquin Valley a fungus has been isolated, an extract of which inhibits the growth of Coccidioides immitis on Sabouraud's medium. An acute toxicity study in mice indicates a certain tolerance of the extract. Tentative identification indicates that the fungus is a penicillium.
M C, EGEBERG, A F, ELCONIN, R O, EGEBERG
openaire +2 more sources
2015
Antifungal drugs used to treat serious fungal disease fall primarily into three drug classes. These classes include the azoles, echinocandins, and polyenes. Both azoles and polyenes target the cell membrane while echinocandins specifically target cell-wall synthesis. Amphotericin B is the primary drug in the polyene arsenal and is considered fungicidal,
LEWIS, RUSSEL EDWARD +1 more
openaire +3 more sources
Antifungal drugs used to treat serious fungal disease fall primarily into three drug classes. These classes include the azoles, echinocandins, and polyenes. Both azoles and polyenes target the cell membrane while echinocandins specifically target cell-wall synthesis. Amphotericin B is the primary drug in the polyene arsenal and is considered fungicidal,
LEWIS, RUSSEL EDWARD +1 more
openaire +3 more sources
The Indian Journal of Pediatrics, 2004
Invasive fungal infections have evolved into significant causes of morbidity and mortality in premature infants, immunocompromised children, and patients receiving immunosuppressive agents. Since the discovery in 1955, amphotericin B has been the cornerstone of antifungal treatment.
Walid, Abuhammour, Eyassu, Habte-Gaber
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Invasive fungal infections have evolved into significant causes of morbidity and mortality in premature infants, immunocompromised children, and patients receiving immunosuppressive agents. Since the discovery in 1955, amphotericin B has been the cornerstone of antifungal treatment.
Walid, Abuhammour, Eyassu, Habte-Gaber
openaire +2 more sources
Resistance to Antifungal Agents
Pediatric Clinics of North America, 1995The marked increase in the number of patients with AIDS and other forms of immunocompromise has resulted in the emergence of fungi as predominant pathogens in many institutions. Unfortunately, with the widespread use of antifungal agents to combat these infections, reports of resistance to antifungal agents have proliferated. In the present environment,
G P, DeMuri, M K, Hostetter
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Current Opinion in Pediatrics, 2013
In recent years there has been an evolution of a better understanding of the pharmacology and clinical indications of existing antifungal agents and also the development of new broad-spectrum triazoles and a newer class of antifungal agents, the echinocandins.
Beatriz, Larru, Theoklis E, Zaoutis
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In recent years there has been an evolution of a better understanding of the pharmacology and clinical indications of existing antifungal agents and also the development of new broad-spectrum triazoles and a newer class of antifungal agents, the echinocandins.
Beatriz, Larru, Theoklis E, Zaoutis
openaire +2 more sources