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Antifungal Susceptibility Testing: A Primer for Clinicians. [PDF]
Open Forum Infectious Diseases, 2021 Abstract Clinicians treating patients with fungal infections may turn to susceptibility testing to obtain information regarding the activity of different antifungals against a specific fungus that has been cultured. These results may then be used to make decisions regarding a patient’s therapy.
Nathan Paul Wiederhold
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Antifungal Susceptibility Testing: Current Approaches. [PDF]
Clinical Microbiology Reviews, 2020 Although not as ubiquitous as antibacterial susceptibility testing, antifungal susceptibility testing (AFST) is a tool of increasing importance in clinical microbiology laboratories. The goal of AFST is to reliably produce MIC values that may be used to guide patient therapy, inform epidemiological studies, and track rates of ...
Shawn R Lockhart, Elizabeth L Berkow
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Antifungal Susceptibility Testing
Infectious Disease Clinics of North America, 2006Antifungal susceptibility testing has been in routine use now for more than 15 years and has become a useful tool for clinicians who are faced with difficult treatment decision. Although most clinicians order susceptibility testing, much confusion still exists regarding the use of the results.
Annette W, Fothergill +2 more
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In Vitro Antifungal Susceptibility Testing
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2001With the rising frequency of fungal infections, as well as increasing reports of resistance to antifungal agents, it is imperative that clinically applicable antifungal susceptibility testing be available. In 1997 the National Committee for Clinical Laboratory Standards published standard guidelines for antifungal susceptibility testing of Candida sp ...
H L, Hoffman, M A, Pfaller
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Biofilms and Antifungal Susceptibility Testing
2016Yeasts and filamentous fungi both exist as single cells and hyphal forms, two morphologies used by most fungal organisms to create a complex multilayered biofilm structure. In this chapter we describe the most widely used assays for the determination of biofilm production and assessment of susceptibility of biofilms to antifungal agents or host ...
Maria, Simitsopoulou +2 more
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Antifungal Susceptibility Testing: A Primer for Clinicians
Pharmacotherapy, 2012Antifungal susceptibility testing is not as commonly performed as antibacterial susceptibility testing. The methodology for detecting antifungal resistance is newer and requires different testing supplies that may not be readily available in a clinical laboratory setting. Breakpoints for molds are lacking.
Audrey Wanger
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Aspergillus – Classification and Antifungal Susceptibilities
Current Pharmaceutical Design, 2013Aspergillus is one of the most important fungal genera for the man, for its industrial use, its ability to spoil food and not least its medical impact as cause of a variety of diseases. Currently hundreds of species of Aspergillus are known; nearly fifty of them are able to cause infections in humans and animals.
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Antifungal Agents and Antifungal Susceptibility Testing
20101 Systemic Antifungal Drugs in Current Use 2 Future Antifungal Drugs 3 Antifungal Susceptibility Testing 4 Methods of Susceptibility Testing Keywords: antifungal agents and antifungal susceptibility testing; systemic antifungal drugs in current use; antifungal mechanisms of action; lipid vehicles for polyenes; unique ...
Sanjay G. Revankar +2 more
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The Evolving Role of Antifungal Susceptibility Testing [PDF]
Pharmacotherapy, 2013 Although increasing numbers of hospital microbiology laboratories are performing antifungal susceptibility testing ( AST ), its routine use is uncommon. The utility of AST is founded on the belief that susceptibility (or resistance) of an agent allows ...
Gregory Eschenauer, Peggy L Carver
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Antifungal Susceptibility Testing Methods
Current Drug Targets, 2005The number of systemically active antifungal agents has increased dramatically in recent years in response to the challenge of invasive mycoses. Additional work is needed to better understand the mechanisms of action of these agents as well as the mechanisms of resistance expressed by the fungal pathogens.
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