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Antifungal susceptibility profiles of 1698 yeast reference strains revealing potential emerging human pathogens. [PDF]
New molecular identification techniques and the increased number of patients with various immune defects or underlying conditions lead to the emergence and/or the description of novel species of human and animal fungal opportunistic pathogens. Antifungal
Marie Desnos-Ollivier +4 more
doaj +2 more sources
Species distribution and
Background In Tanzania, little is known on the species distribution and antifungal susceptibility profiles of yeast isolates from HIV-infected patients with primary and recurrent oropharyngeal candidiasis. Methods A total of 296 clinical oral yeasts were
Rijs Antonius JMM +9 more
doaj +3 more sources
A Practical Guide to Antifungal Susceptibility Testing
We review antifungal susceptibility testing and the development of clinical breakpoints, and detail an approach to using antifungal susceptibility results when breakpoints have not been defined. This information may prove helpful when selecting therapy for invasive fungal infections in children.
William R Otto +2 more
openaire +4 more sources
Standardization of antifungal susceptibility testing [PDF]
The application of in-vitro antifungal susceptibility testing to clinical research and to the guidance of antifungal therapy has been limited by a lack of reproducibility and uncertain clinical relevance. As a result of studies of the identified variables impacting on in-vitro susceptibility results, the National Committee for Clinical Laboratory ...
M G, Cormican, M A, Pfaller
openaire +3 more sources
The clinical involvement and antifungal susceptibility of Aspergillus section Circumdati are poorly known. We analyzed 52 isolates, including 48 clinical isolates, belonging to 9 species inside the section Circumdati.
R. Piarroux +15 more
core +1 more source
Autophagy Alters the Susceptibility of Candida albicans Biofilms to Antifungal Agents
Candida albicans (C. albicans) reigns as a major cause of clinical candidiasis. C. albicans biofilms are known to increase resistance to antifungal agents, making biofilm-related infections particularly challenging to treat.
Jiadi Shen +6 more
doaj +1 more source
Antifungal susceptibility testing of yeasts and the development of interpretive breakpoints are nowadays very important topics both for the increasing incidence of invasive mycoses and number of available antifungal drugs and for the appearance of ...
Esther Manso +6 more
doaj +1 more source
Fluconazole Resistance and Heteroresistance in Cryptococcus spp.: Mechanisms and Implications [PDF]
The reference methodology for evaluating antifungal susceptibility is based on determining the minimum inhibitory concentration (MIC), which is the lowest drug concentration capable of inhibiting fungal growth.
Izabela de Mesquita Bárcia Moreira +10 more
doaj +1 more source
Fungal keratitis (FK) is an invasive infection of the cornea primarily associated with Aspergillus and Fusarium species. FK is treated empirically with a limited selection of topical antifungals with varying levels of success.
Darby Roberts +3 more
doaj +1 more source
With the increase in invasive fungal infections due to Candida species and resistance to antifungal therapy, in vitro antifungal susceptibility testing is becoming an important part of clinical microbiology laboratories.
Sidhartha Giri, Anupma Jyoti Kindo
doaj +1 more source

