Results 21 to 30 of about 724,601 (205)

Pharmacodynamic Effects of Simulated Standard Doses of Antifungal Drugs against Aspergillus Species in a New In Vitro Pharmacokinetic/Pharmacodynamic Model [PDF]

, 2011
In conventional MIC tests, fungi are exposed to constant drug concentrations, whereas in vivo, fungi are exposed to changing drug concentrations.
Thomas J. Walsh, Emmanuel Roilides, Aristea Velegraki, Walsh, Thomas, Zerva, Loukia, Meletiadis, Joseph, Joseph Meletiadis, Roilides, Emmanuel, Rafal Al-Saigh, Velegraki, Aristea, Loukia Zerva, Al Saigh, Rafal   +11 more
core   +1 more source

How to interpret MICs of antifungal compounds according to the revised clinical breakpoints v. 10.0 European committee on antimicrobial susceptibility testing (EUCAST). [PDF]

, 2020
BACKGROUND: EUCAST has revised the definition of the susceptibility category I from 'Intermediate' to 'Susceptible, Increased exposure'. This implies that I can be used where the drug concentration at the site of infection is high, either because of dose
Mares, M., Kahlmeter, G., Guinea, J., Subcommittee on Antifungal Susceptibility Testing (AFST) of the ESCMID European Committee for Antimicrobial Susceptibility Testing (EUCAST), Friberg, N., Meletiadis, J., Arendrup, M.C.   +6 more
core   +1 more source

Use of volatile fingerprints for rapid screening of antifungal agents for efficacy against dermatophyte Trichophyton species [PDF]

, 2010
The potential of using an electronic nose (E-nose) as a rapid technique for screening the responses of dermatophytes to antifungal agents was studied.
Barr, Hugh, Magan, Naresh, Sahgal, Natasha, Naraghi, Kamran, Adriaans, Beverley, Natasha Sahgal, Beverley Adriaans, Kamran Naraghi, Hugh Barr, Naresh Magan   +9 more
core   +1 more source

Clinical utility of antifungal susceptibility testing

JAC-Antimicrobial Resistance, 2022
Abstract Invasive fungal diseases cause significant morbidity and mortality, in particular affecting immunocompromised patients. Resistant organisms are of increasing importance, yet there are many notable differences in the ability to both perform and interpret antifungal susceptibility testing compared with bacteria. In this review,
Todd P McCarty, Paul M Luethy, John W Baddley, Peter G Pappas   +3 more
openaire   +2 more sources

Antifungal susceptibility ofMalassezia pachydermatisbiofilm [PDF]

Medical Mycology, 2013
Antifungal resistance has been associated with biofilm formation in many microorganisms, but not yet in Malassezia pachydermatis. This saprophytic yeast can cause otitis and dermatitis in dogs and has emerged as an important human pathogen, responsible for systemic infections in neonates in intensive care units. This study aims to evaluate the in vitro
Figueredo LA, CAFARCHIA, Claudia, OTRANTO, Domenico   +2 more
openaire   +3 more sources

Susceptibility Profile of Candida albicans Biofilms on Polyvinyl Chloride Endotracheal Tube to Antifungal Azoles

, 2020
One of the most prevalent causative organisms in human fungal infections is Candida albicans. The extensive utility of medical devices such as endotracheal tube has resulted in the increased cases of fungal infections.
Nelson R. Villarante, Isidro C. Sia, Sia, Isidro C., Nina G. Gloriani, Villarante, Nelson R., Salazar, Pauline Bridgette D., Pauline Bridgette D. Salazar, Sumalapao, Derick Erl P., Alegre, Frederico Martin D., Derick Erl P. Sumalapao, Frederico Martin D. Alegre, Gloriani, Nina G.   +11 more
core   +1 more source

ABC transporters and azole susceptibility in laboratory strains of the wheat pathogen Mycosphearella graminicola [PDF]

, 2002
Laboratory strains of Mycosphaerella graminicola with decreased susceptibilities to the azole antifungal agent cyproconazole showed a multidrug resistance phenotype by exhibiting cross-resistance to an unrelated chemical, cycloheximide or rhodamine 6G ...
Nistelrooy, J.G.M., Van, Zwiers, L.H., Stergiopoulos, I., Waard, M.A., De, Lute-harm Zwiers, Johannes G. M. Van Nistelrooy, Van Nistelrooy, Maarten A. De Waard, Johannes G. M, Ioannis Stergiopoulos   +9 more
core   +1 more source

Isolation, speciation and antifungal susceptibility testing of Candida isolates from various clinical specimens at a tertiary care hospital, Nepal

BMC Research Notes, 2017
Background Candida species are responsible for various clinical infections ranging from mucocutaneous infection to life threatening invasive diseases along with increased resistance to antifungal drugs has made a serious concern. Resistance to antifungal
Sundar Khadka, Jeevan Bahadur Sherchand, Bharat Mani Pokhrel, Keshab Parajuli, Shyam Kumar Mishra, Sangita Sharma, Niranjan Shah, Hari Prasad Kattel, Subhash Dhital, Sulochana Khatiwada, Narayan Parajuli, Manoj Pradhan, Basista Prasad Rijal   +12 more
doaj   +1 more source

Patterns of culture positivity and antifungal sensitivity in dermatophytosis

MGM Journal of Medical Sciences, 2019
Background: Antifungal drug resistance and a lack of clinical response in 20% of cases of dermatophytosis calls for an evaluation of resistant dermatophytes using a standardized simple and reproducible in vitro assay, to allow clinician to select the ...
Vedant Ghuse, Shylaja Someshwar, Hemangi Jerajani   +2 more
doaj   +1 more source

Impact of the Disk Diffusion Test on Fluconazole De-Escalation in Patients with Candidemia

Journal of Fungi, 2022
Disk diffusion (DD) is a simple antifungal susceptibility method for Candida. This study examined the impact of fluconazole DD testing on antifungal de-escalation.
Suchavadee Tantasuwan, Piriyaporn Chongtrakool, Amiroh Waesamaae, Methee Chayakulkeeree   +3 more
doaj   +1 more source