Results 91 to 100 of about 27,323 (239)

Design, Synthesis, Cytotoxicity Assessment, and Molecular Docking of Novel Triazolopyrimidines as Potent Cyclin‐Dependent Kinase 4 Inhibitors

ChemistryOpen, EarlyView.
A novel series of 1,5‐dihydro‐[1,2,4]triazolo[4,3‐a]pyrimidines (5a–g) is synthesized and evaluated as potential CDK4 inhibitors. Compounds 5c and 5d exhibit strong cytotoxicity toward HepG2 and MCF‐7 cells with IC50 ≈ 1–2 µM, comparable to doxorubicin.
Tariq Z. Abolibda, Sami A. Al‐Hussain, Basant Farag, Mohamed El‐Naggar, Magdi E. A. Zaki, Emad S. A. Alhazmi, Adel S. M. Almohammadi, Sobhi M. Gomha   +7 more
wiley   +1 more source

Comparative evaluation of antifungal susceptibility testing methods for Rhizopus species isolates. [PDF]

Curr Med Mycol, 2023
Hasan MS, Gupta P, Banerjee G.
europepmc   +1 more source

Antifungal susceptibility tests [PDF]

Antimicrobial Agents and Chemotherapy, 1987
openaire   +2 more sources

Omics Insights Into the Effects of Highbush Blueberry and Cranberry Crop Agroecosystems on Honey Bee Health and Physiology

PROTEOMICS, EarlyView.
ABSTRACT Honey bees (Apis mellifera) are vital pollinators in fruit‐producing agroecosystems like highbush blueberry (HBB) and cranberry (CRA). However, their health is threatened by multiple interacting stressors, including pesticides, pathogens, and nutritional changes.
Huan Zhong, Yuming Shi, Aleksandra Kozlova, Renata Moravcova, Jason C. Rogalski, Aidan Jamieson, Lance Lansing, Kyung‐Mee Moon, Xiaojing Yuan, Amanda S. Gregoris, Heather Higo, Julia Common, Ida M. Conflitti, Mateus Pepinelli, Lan Tran, Morgan Cunningham, Hosna Jabbari, Syed Abbas Bukhari, Sarah K. French, Rodrigo Ortega Polo, Shelley E. Hoover, Stephen F. Pernal, Pierre Giovenazzo, M. Marta Guarna, Amro Zayed, Leonard J. Foster   +25 more
wiley   +1 more source

Study of Candida Bloodstream Infections in Surgical Intensive Care Unit Patients and Susceptibility Profile of the Isolates [PDF]

Journal of Krishna Institute of Medical Sciences University, 2015
Background: The increased incidence of fungal infections in the past two decades has been overwhelming. Despite the fact that invasive fungal infections are still under-diagnosed and underreported, bloodstream infection due to Candida is now being ...
Vijaya S. Rajmane , Shivkumar T. Rajmane, Shivaji T. Mohite , Vinayak V. Raje   +3 more
doaj  

A Practical Guide to Antifungal Susceptibility Testing. [PDF]

J Pediatric Infect Dis Soc, 2023
Otto WR, Arendrup MC, Fisher BT.
europepmc   +1 more source

Contaminants of emerging concern in agricultural soils: Current understanding, overlooked issues, and future priorities

PLANTS, PEOPLE, PLANET, EarlyView.
Contaminants of emerging concern (CECs) in agriculture represent a growing global challenge for food safety and public health. In this review, we synthesized evidence on how substances such as pharmaceuticals, microplastics, and per‐ and polyfluoroalkyl substances (PFAS) enter soils, accumulate in crops, and affect ecological and human health. We found
Laura J. Carter, Evyatar Ben Mordechay, Benny Chefetz, Zeyou Chen, Xinyi Cui, Jay Gan, Hui Li, Audrey Moores, Xiaoyu Gao   +8 more
wiley   +1 more source

In-vitro Susceptibility Testing of Dermatophytes Isolated in Delhi (India) Against Five Antifungal Drugs

Medical and Health Science Journal
Background: Over the past few decades, cases of dermatophytosis have been on the rise. Recently, the introduction of newer, less toxic antifungal drugs has improved treatment options. However, the prolonged use of antifungals has led to the emergence of
Shyama Datt, Thakur Datt, N.P Singh
doaj   +1 more source

Advancing Sclerotinia risk forecasting for winter rapeseed in Germany: integrating crop phenology and disease development into a decision support system

Pest Management Science, EarlyView.
Integrating crop phenology and sclerotia germination models into SkleroPro improved Sclerotinia risk prediction accuracy from 34% to 66%, optimizing fungicide timing and supporting sustainable winter rapeseed production. Abstract BACKGROUND Sclerotinia stem rot, caused by Sclerotinia sclerotiorum, threatens winter rapeseed (Brassica napus) production ...
Vera Krause, Nazanin Zamani‐Noor, Lena Müller, Hella Kehlenbeck, Anto Raja Dominic   +4 more
wiley   +1 more source

A study on biofilm production and antifungal drug resistance among Candida species from vulvovaginal and bloodstream infections

Infection and Drug Resistance, 2018
Sanyuktha Tulasidas,1 Pooja Rao,2 Sevitha Bhat,2 Radhakrishna Manipura1 1Department of Microbiology, Kasturba Medical College, Manipal Academy of Higher Education, Mangalore, Manipal, India; 2Department of Microbiology, Kasturba Medical College, Manipal ...
Tulasidas S, Rao P, Bhat S, Manipura R
doaj