Results 261 to 266 of about 63,671 (266)

Resistance and tolerance mechanisms to antifungal drugs in fungal pathogens

Mycologist, 2003
Fungal pathogens are using several mechanisms to circumvent the inhibitory actions of antifungal drugs. The variety of these mechanisms was revealed in recent years by several laboratories with molecular approaches. Besides the identification of genes involved in antifungal drug resistance and the discovery of alternative pathways of resistance (i.e ...
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Unveiling antifungal resistance and biocide tolerance in clinical isolates of Candida spp

Future Microbiology
Candidiasis, caused by Candida spp. is an opportunistic infection with significant healthcare risks, worsened by trends in antifungal resistance. This study aimed to evaluate the antifungal susceptibility profile, investigate resistance mechanisms, assess efflux pump activity, and examine biocide tolerance in clinical Candida isolates.A total of 100 ...
Jamile De Paiva Macedo, Aripuana Aranha Sakurada Watanabe, Alessandra Barbosa Ferreira Machado, Cláudio Galuppo Diniz, Vania Lucia Da Silva, Vanessa Cordeiro Dias   +5 more
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Genetic Tolerance to Rose Bengal Photodynamic Therapy and Antifungal Clinical Application for Onychomycosis

Advanced Therapeutics, 2018
AbstractPhotodynamic therapy (PDT) with rose bengal has seen increasing use in clinical applications and has shown effective antifungal capacity in vitro. However, there is limited understanding of the effects of this emerging therapy at a genetic level.
Jessica Houang, Gabriel G. Perrone, Christian Pedrinazzi, Leonardo Longo, Damia Mawad, Philip C. Boughton, Andrew J. Ruys, Antonio Lauto   +7 more
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Evolution of antifungal drug tolerance in Candida albicans

2019
Mestrado em Biomedicina ...
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Quantifying and Mitigating Antifungal Tolerance in the Pathogenic Yeast Candida auris

Candida auris is an emerging pathogen that has been detected on five continents and is linked to resistance against the main three classes of antifungal drugs used to treat invasive infections, leading to healthcare-associated outbreaks. Tolerance refers to the ability of a drug-susceptible fungal strain to grow slowly in the presence of an antifungal ...
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Isavuconazole provides effective and tolerable antifungal prophylaxis for patients with acute myeloid leukemia

Leukemia Research
Cameron J. Hunter, Andrew Chou, Heidi Roeder, William Eighmy, Jan Philipp Bewersdorf, Lourdes Mendez, Maximilian Stahl, Nikolai A. Podoltsev, Amer M. Zeidan, Rory M. Shallis   +9 more
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