Acquisition of antibody isotypes against Plasmodium falciparum blood stage antigens in a birth cohort. [PDF]
Information on the period during which infants lose their maternally derived antibodies to malaria and begin to acquire naturally their own immune responses against parasite antigens is crucial for understanding when malaria vaccines may be best ...
Duah, NO +7 more
core +1 more source
Long-lived antibody and B Cell memory responses to the human malaria parasites, Plasmodium falciparum and Plasmodium vivax. [PDF]
Antibodies constitute a critical component of the naturally acquired immunity that develops following frequent exposure to malaria. However, specific antibody titres have been reported to decline rapidly in the absence of reinfection, supporting the ...
Thaikla, Kanitta +39 more
core +2 more sources
. The aim of this study was to compare the efficiency of different methods applied for the diagnostics of brucellosis. Huddlson and Wright reactions, RoseBengal test, ELISA-based test system (IgG determination), and a test for antigen-binding lymphocytes
B. V. Karalnik +6 more
doaj +1 more source
Immune-Complex Mimics as a Molecular Platform for Adjuvant-Free Vaccine Delivery [PDF]
Protein-based vaccine development faces the difficult challenge of finding robust yet non-toxic adjuvants suitable for humans. Here, using a molecular engineering approach, we have developed a molecular platform for generating self-adjuvanting immunogens
Stylianou, E +26 more
core +2 more sources
Influence of nanoparticles of colloid gold (CG) and silver (CS) on immunobiological properties of antigens and possibility of their application as adjuvants for antibody formation stimulation were studied.
M. N. Kireev +5 more
doaj +1 more source
Field comparison of circulating antibody assays versus circulating antigen assays for the detection of Schistosomiasis japonica in endemic areas of China [PDF]
Schistosomiasis remains a serious public health problem in affected countries, and routine, highly sensitive and cost-effective diagnostic methods are lacking.
Peter Steinmann +23 more
core +1 more source
In vivo safety profile of a CSPG4-directed IgE antibody in an immunocompetent rat model
IgE monoclonal antibodies hold great potential for cancer therapy. Preclinical in vivo systems, particularly those in which the antibody recognizes the host species target antigen and binds to cognate Fc receptors, are often the closest approximation to ...
Iwan P. Williams +12 more
doaj +1 more source
Recent Advances in Quenchbody, a Fluorescent Immunosensor
The detection of viruses, disease biomarkers, physiologically active substances, drugs, and chemicals is of great significance in many areas of our lives.
Jinhua Dong, Hiroshi Ueda
doaj +1 more source
Antigen-specific influence of GM/KM allotypes on IgG isotypes and association of GM allotypes with susceptibility to
Background Plasmodium falciparum malaria is a complex disease in which genetic and environmental factors influence susceptibility. IgG isotypes are in part genetically controlled, and GM/KM allotypes are believed to be involved in this control.
Thor G Theander +34 more
core +1 more source
A conglutination test for rapid detection of antibodies against Babesia bigemina [PDF]
A rapid conglutination test (RCT) with performance comparable to the indirect fluorescent antibody technique (IFAT) was developed to detect antibodies against Babesia bigemina (B. bigemina-RCT). The B.
Claudio R. Madruga +3 more
doaj +1 more source

