Results 11 to 20 of about 2,779,749 (199)

Bacteroides thetaiotaomicron-derived outer membrane vesicles promote regulatory dendritic cell responses in health but not in inflammatory bowel disease

Microbiome, 2020
Background Bacteroides thetaiotaomicron (Bt) is a prominent member of the human intestinal microbiota that, like all gram-negative bacteria, naturally generates nanosized outer membrane vesicles (OMVs) which bud off from the cell surface.
Lydia Durant, Régis Stentz, Alistair Noble, Johanne Brooks, Nadezhda Gicheva, Durga Reddi, Matthew J. O’Connor, Lesley Hoyles, Anne L. McCartney, Ripple Man, E. Tobias Pring, Stella Dilke, Philip Hendy, Jonathan P. Segal, Dennis N. F. Lim, Ravi Misra, Ailsa L. Hart, Naila Arebi, Simon R. Carding, Stella C. Knight   +19 more
doaj   +1 more source

Screening of medicinal mushroom strains with antimicrobial activity and polysaccharides production

Türk Biyokimya Dergisi, 2023
This study aimed to determine the antimicrobial activity of culture fluid and mycelial mass of selected Hericium strains from the IBK Mushroom Culture Collection (Kyiv, Ukraine) against bacteria and fungi, as well as to evaluate the potential of these ...
Narmuratova Zhanar, Bisko Nina, Mustafin Kairat, Al-Maali Galeb, Kerner Alina, Bondaruk Svitlana, Suleimenova Zhanara, Kalieva Aigul, Akhmetsadykov Nurlan, Zhakipbekova Aigerim, Lomberg Margarita   +10 more
doaj   +1 more source

Application of Cellular Technologies to the Experimental Treatment of Destructive Inflammatory Arthropathies

Central Asian Journal of Global Health, 2014
Introduction. The treatment of destructive inflammatory joint diseases (arthropathies) is one of the issues of current interest in modern medicine.
Marzhan Kaulambayeva, Galina Fedotovskikh, Anara Nurmukhambetova   +2 more
doaj   +1 more source

Functional Characterization of a Dual Enhancer/Promoter Regulatory Element Leading Human CD69 Expression

Frontiers in Genetics, 2020
The CD69 gene encodes a C-type lectin glycoprotein with immune regulatory properties which is expressed on the cell surfaces of all activated hematopoietic cells.
Jennifer Redondo-Antón, MG Fontela, Laura Notario, Raúl Torres-Ruiz, Sandra Rodríguez-Perales, Elena Lorente, Pilar Lauzurica   +6 more
doaj   +1 more source

SARS-CoV-2 spike-ferritin-nanoparticle adjuvanted with ALFQ induces long-lived plasma cells and cross-neutralizing antibodies

npj Vaccines, 2023
This study demonstrates the impact of adjuvant on the development of T follicular helper (Tfh) and B cells, and their influence on antibody responses in mice vaccinated with SARS-CoV-2-spike-ferritin-nanoparticle (SpFN) adjuvanted with either Army ...
Shikha Shrivastava, Joshua M. Carmen, Zhongyan Lu, Shraddha Basu, Rajeshwer S. Sankhala, Wei-Hung Chen, Phuong Nguyen, William C. Chang, Jocelyn King, Courtney Corbitt, Sandra Mayer, Jessica S. Bolton, Alexander Anderson, Isabella Swafford, Guillermo D. Terriquez, Hung V. Trinh, Jiae Kim, Ousman Jobe, Dominic Paquin-Proulx, Gary, R. Matyas, Gregory D. Gromowski, Jeffrey R. Currier, Elke Bergmann-Leitner, Kayvon Modjarrad, Nelson L. Michael, M. Gordon Joyce, Allison M. W. Malloy, Mangala Rao   +27 more
doaj   +1 more source

Preparation and evaluation of Salmonella Enteritidis antigen conjugated with nanogold for screening of poultry flocks [PDF]

Veterinary World, 2017
Aim: The present work aimed to develop lateral flow immunochromatographic strip (ICS) test for detection of Salmonella Enteritidis (SE) specific antibodies in chicken sera.
Hazem Mohammed Ibrahim, Rafik Hamed Sayed, Wafaa Ragab Abdel-Aziz, Rafik Tawfik Soliman   +3 more
doaj   +1 more source

Engineering of an Avidity-Optimized CD19-Specific Parallel Chimeric Antigen Receptor That Delivers Dual CD28 and 4-1BB Co-Stimulation

Frontiers in Immunology, 2022
Co-stimulation is critical to the function of chimeric antigen receptor (CAR) T-cells. Previously, we demonstrated that dual co-stimulation can be effectively harnessed by a parallel (p)CAR architecture in which a CD28-containing second generation CAR is
Leena Halim, Kushal K. Das, Daniel Larcombe-Young, Adam Ajina, Andrea Candelli, Reuben Benjamin, Reuben Benjamin, Richard Dillon, Richard Dillon, David M. Davies, John Maher, John Maher, John Maher, John Maher   +13 more
doaj   +1 more source

Antigenic Variability [PDF]

Frontiers in Immunology, 2020
Protective vaccines for hypervariable pathogens are urgently needed. It has been proposed that amputating highly variable epitopes from vaccine antigens would induce the production of broadly protective antibodies targeting conserved epitopes. However, so far, these approaches have failed, partially because conserved epitopes are occluded in vivo and ...
openaire   +3 more sources

Antigen Stability Controls Antigen Presentation [PDF]

Journal of Biological Chemistry, 2004
We investigated whether protein stability controls antigen presentation using a four disulfide-containing snake toxin and three derivatives carrying one or two mutations (L1A, L1A/H4Y, and H4Y). These mutations were anticipated to increase (H4Y) or decrease (L1A) the antigen non-covalent stabilizing interactions, H4Y being naturally and frequently ...
Jean-Luc Tarride, Michel Desmadril, Denis Servent, André Ménez, Michel Léonetti, Gervaise Moine, Robert Thai   +6 more
openaire   +3 more sources

Panproteome-wide analysis of antibody responses to whole cell pneumococcal vaccination

eLife, 2018
Pneumococcal whole cell vaccines (WCVs) could cost-effectively protect against a greater strain diversity than current capsule-based vaccines. Immunoglobulin G (IgG) responses to a WCV were characterised by applying longitudinally-sampled sera, available
Joseph J Campo, Timothy Q Le, Jozelyn V Pablo, Christopher Hung, Andy A Teng, Hervé Tettelin, Andrea Tate, William P Hanage, Mark R Alderson, Xiaowu Liang, Richard Malley, Marc Lipsitch, Nicholas J Croucher   +12 more
doaj   +1 more source