Results 11 to 20 of about 3,861,164 (348)

Dendritic cell subsets in cancer immunity and tumor antigen sensing

Cellular & Molecular Immunology, 2023
Dendritic cells (DCs) exhibit a specialized antigen-presenting function and play crucial roles in both innate and adaptive immune responses. Due to their ability to cross-present tumor cell-associated antigens to naïve T cells, DCs are instrumental in ...
A. Del Prete, V. Salvi, A. Soriani, Mattia Laffranchi, F. Sozio, D. Bosisio, S. Sozzani   +6 more
semanticscholar   +1 more source

Bioengineered bacteria-derived outer membrane vesicles as a versatile antigen display platform for tumor vaccination via Plug-and-Display technology

Nature Communications, 2021
An effective tumor vaccine vector that can rapidly display neoantigens is urgently needed. Outer membrane vesicles (OMVs) can strongly activate the innate immune system and are qualified as immunoadjuvants. Here, we describe a versatile OMV-based vaccine
Keman Cheng, Ruifang Zhao, Yao Li, Yingqiu Qi, Yazhou Wang, Yinlong Zhang, Hao Qin, Yuting Qin, Long Chen, Chen Li, Jie Liang, Yujing Li, Jiaqi Xu, Xuexiang Han, G. Anderson, Jian Shi, L. Ren, Xiao Zhao, Guangjun Nie   +18 more
semanticscholar   +1 more source

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha

Journal of Experimental Medicine, 1994
Using granulocyte/macrophage colony-stimulating factor (GM-CSF) and interleukin 4 we have established dendritic cell (DC) lines from blood mononuclear cells that maintain the antigen capturing and processing capacity characteristic of immature dendritic ...
F. Sallusto, A. Lanzavecchia
semanticscholar   +1 more source

Antioxidant and antimicrobial potential of Ganoderma lucidum and Trametes versicolor

Türk Biyokimya Dergisi, 2022
The majority of research programs had been focused on extract from the fruiting body. However, fungal mycelium obtained by submerged cultivation also has higher pharmacological potential.
Mustafin Kairat, Bisko Nina, Blieva Raushan, Al-Maali Galeb, Krupodorova Tatyana, Narmuratova Zhanar, Saduyeva Zhazira, Zhakipbekova Aigerim   +7 more
doaj   +1 more source

Chimeric Antigen Receptor Therapy.

New England Journal of Medicine, 2018
Chimeric Antigen Receptor T Cells This review addresses T-cell engineering and synthetic immunity, with a focus on producing durable remissions in patients with treatment-refractory tumors.
C. June, M. Sadelain
semanticscholar   +1 more source

Application of Cellular Technologies to the Experimental Treatment of Destructive Inflammatory Arthropathies

Central Asian Journal of Global Health, 2014
Introduction. The treatment of destructive inflammatory joint diseases (arthropathies) is one of the issues of current interest in modern medicine.
Marzhan Kaulambayeva, Galina Fedotovskikh, Anara Nurmukhambetova   +2 more
doaj   +1 more source

Bacteroides thetaiotaomicron-derived outer membrane vesicles promote regulatory dendritic cell responses in health but not in inflammatory bowel disease

Microbiome, 2020
Background Bacteroides thetaiotaomicron (Bt) is a prominent member of the human intestinal microbiota that, like all gram-negative bacteria, naturally generates nanosized outer membrane vesicles (OMVs) which bud off from the cell surface.
Lydia Durant, Régis Stentz, Alistair Noble, Johanne Brooks, Nadezhda Gicheva, Durga Reddi, Matthew J. O’Connor, Lesley Hoyles, Anne L. McCartney, Ripple Man, E. Tobias Pring, Stella Dilke, Philip Hendy, Jonathan P. Segal, Dennis N. F. Lim, Ravi Misra, Ailsa L. Hart, Naila Arebi, Simon R. Carding, Stella C. Knight   +19 more
doaj   +1 more source

Functional Characterization of a Dual Enhancer/Promoter Regulatory Element Leading Human CD69 Expression

Frontiers in Genetics, 2020
The CD69 gene encodes a C-type lectin glycoprotein with immune regulatory properties which is expressed on the cell surfaces of all activated hematopoietic cells.
Jennifer Redondo-Antón, MG Fontela, Laura Notario, Raúl Torres-Ruiz, Sandra Rodríguez-Perales, Elena Lorente, Pilar Lauzurica   +6 more
doaj   +1 more source

Screening of medicinal mushroom strains with antimicrobial activity and polysaccharides production

Türk Biyokimya Dergisi, 2023
This study aimed to determine the antimicrobial activity of culture fluid and mycelial mass of selected Hericium strains from the IBK Mushroom Culture Collection (Kyiv, Ukraine) against bacteria and fungi, as well as to evaluate the potential of these ...
Narmuratova Zhanar, Bisko Nina, Mustafin Kairat, Al-Maali Galeb, Kerner Alina, Bondaruk Svitlana, Suleimenova Zhanara, Kalieva Aigul, Akhmetsadykov Nurlan, Zhakipbekova Aigerim, Lomberg Margarita   +10 more
doaj   +1 more source

Adsorption of organochlorinated pesticides: Adsorption kinetic and adsorption isotherm study

Results in Engineering, 2023
Adsorption of organochlorine pesticides (OCPs) on 4 contrasted activated carbons (ACs) and biochars (BCs) and 5 different basic substances of soil organic matter (SOM) in aqueous media was investigated using adsorption kinetic and isotherm study.
Farida Amutova, Stefan Jurjanz, Nurlan Akhmetsadykov, Maira Kazankapova, Angelina Razafitianamaharavo, Aurélien Renard, Moldir Nurseitova, Gaukhar Konuspayeva, Matthieu Delannoy   +8 more
doaj   +1 more source