Results 11 to 20 of about 3,619,273 (388)

Diverse Humoral Immune Responses in Younger and Older Adult COVID-19 Patients

mBio, 2021
As numerous viral variants continue to emerge in the coronavirus disease 2019 (COVID-19) pandemic, determining antibody reactivity to SARS-CoV-2 epitopes becomes essential in discerning changes in the immune response to infection over time.
Jennifer M. Sasson, Joseph J. Campo, Rebecca M. Carpenter, Mary K. Young, Arlo Z. Randall, Krista Trappl-Kimmons, Amit Oberai, Christopher Hung, Joshua Edgar, Andy A. Teng, Jozelyn V. Pablo, Xiaowu Liang, Angela Yee, William A. Petri, David Camerini   +14 more
doaj   +1 more source

Mapping SARS-CoV-2 Antibody Epitopes in COVID-19 Patients with a Multi-Coronavirus Protein Microarray

Microbiology Spectrum, 2021
The rapid worldwide spread of SARS-CoV-2 has accelerated research and development for controlling the COVID-19 pandemic. A multi-coronavirus protein microarray was created containing full-length proteins, overlapping protein fragments of various lengths,
David Camerini, Arlo Z. Randall, Krista Trappl-Kimmons, Amit Oberai, Christopher Hung, Joshua Edgar, Adam Shandling, Vu Huynh, Andy A. Teng, Gary Hermanson, Jozelyn V. Pablo, Megan M. Stumpf, Sandra N. Lester, Jennifer Harcourt, Azaibi Tamin, Mohammed Rasheed, Natalie J. Thornburg, Panayampalli S. Satheshkumar, Xiaowu Liang, Richard B. Kennedy, Angela Yee, Michael Townsend, Joseph J. Campo   +22 more
doaj   +1 more source

Simultaneous genotyping for human platelet antigen systems and HLA-A and HLA-B loci by targeted next-generation sequencing

Frontiers in Immunology, 2022
In order to treat the alloimmunization platelet transfusion refractoriness (PTR), human leukocyte antigen (HLA)-type and/or human platelet antigen (HPA)-type matched platelets between donors and patients are usually used.
Jielin Wang, Jielin Wang, Xuan You, Xuan You, Yanmin He, Yanmin He, Xiaozhen Hong, Xiaozhen Hong, Ji He, Ji He, Sudan Tao, Sudan Tao, Faming Zhu, Faming Zhu   +13 more
doaj   +1 more source

Application efficiency of probiotics in poultry

Алматы технологиялық университетінің хабаршысы, 2021
Due to the growing demand for high-quality poultry and eggs in Kazakhstan, the transition to eco-friendly production is more urgent than ever. The use of probiotics in poultry farms can ensure product safety and economic efficiency. This article presents
N. Zh. Begdildayeva, Sh. N. Akhmetsadykova, A. K. Kudaibergenova, N. N. Akhmetsadykov   +3 more
doaj   +1 more source

TruNeo: an integrated pipeline improves personalized true tumor neoantigen identification

BMC Bioinformatics, 2020
Background Neoantigen-based personal vaccines and adoptive T cell immunotherapy have shown high efficacy as a cancer treatment in clinical trials. Algorithms for the accurate prediction of neoantigens have played a pivotal role in such studies.
Yunxia Tang, Yu Wang, Jiaqian Wang, Miao Li, Linmin Peng, Guochao Wei, Yixing Zhang, Jin Li, Zhibo Gao   +8 more
doaj   +1 more source

In Vitro Priming of Human T Cells by Dendritic Cells Provides a Screening Tool for Candidate Vaccines for Burkholderia pseudomallei

Vaccines, 2021
Murine dendritic cells, when pulsed with heat-killed Burkholderia pseudomallei and used to immunise naïve mice, have previously been shown to induce protective immunity in vivo. We have now demonstrated the in vitro priming of naïve human T cells against
Durga Reddi, Lydia Durant, David Bernardo, Alistair Noble, Nicholas R. English, Philip Hendy, Graeme C. Clark, Joann L. Prior, Ethel Diane Williamson, Stella C. Knight   +9 more
doaj   +1 more source

What are the challenges for implementing an “organic label” to camel milk?

Frontiers in Nutrition, 2023
Increasing demand for camel’s milk worldwide occurred in the context of the development of the organic sector in agriculture. The implementation of an organic label for camel milk has never been established. However, the creation of such a label faces to
Gaukhar Konuspayeva, Gaukhar Konuspayeva, Bernard Faye, Moldir Nurseitova, Shynar Akhmetsadykova, Shynar Akhmetsadykova   +5 more
doaj   +1 more source

Bioengineered bacteria-derived outer membrane vesicles as a versatile antigen display platform for tumor vaccination via Plug-and-Display technology

Nature Communications, 2021
An effective tumor vaccine vector that can rapidly display neoantigens is urgently needed. Outer membrane vesicles (OMVs) can strongly activate the innate immune system and are qualified as immunoadjuvants. Here, we describe a versatile OMV-based vaccine
Keman Cheng, Ruifang Zhao, Yao Li, Yingqiu Qi, Yazhou Wang, Yinlong Zhang, Hao Qin, Yuting Qin, Long Chen, Chen Li, Jie Liang, Yujing Li, Jiaqi Xu, Xuexiang Han, G. Anderson, Jian Shi, L. Ren, Xiao Zhao, Guangjun Nie   +18 more
semanticscholar   +1 more source

Proteome-wide analysis of a malaria vaccine study reveals personalized humoral immune profiles in Tanzanian adults

eLife, 2020
Tanzanian adult male volunteers were immunized by direct venous inoculation with radiation-attenuated, aseptic, purified, cryopreserved Plasmodium falciparum (Pf) sporozoites (PfSPZ Vaccine) and protective efficacy assessed by homologous controlled human
Flavia Camponovo, Joseph J Campo, Timothy Q Le, Amit Oberai, Christopher Hung, Jozelyn V Pablo, Andy A Teng, Xiaowu Liang, B Kim Lee Sim, Said Jongo, Salim Abdulla, Marcel Tanner, Stephen L Hoffman, Claudia Daubenberger, Melissa A Penny   +14 more
doaj   +1 more source

Bystander B cells rapidly acquire antigen receptors from activated B cells by membrane transfer: a novel mechanism for enhancing specific antigen presentation [PDF]

, 2007
The B cell antigen receptor (BCR) efficiently facilitates the capture and processing of a specific antigen for presentation on MHC class II molecules to antigen specific CD4+ T cells (1).
Ben J. C. Quah, Christopher R. Parish, Klaus I. Matthaei, Mark D. Hulett, Vaughan P. Barlow, Virginia McPhun   +5 more
core   +2 more sources