Results 61 to 70 of about 2,264,666 (258)
Prevalence of Group A Streptococcal Carriage Rate in Asymptomatic Children [PDF]
National Journal of Laboratory Medicine, 2019 Introduction: Streptococcus pyogenes is a Gram positive cocci causing respiratory infections commonly in children. Throat carriers are children in whom the organism is isolated from throat swab specimens in the absence of symptoms.
Krishnarao Arthi, S Geetha Banu
doaj +1 more source
Computational model for tumor response to adoptive cell transfer therapy [PDF]
arXiv, 2022 One of the barriers to the development of effective adoptive cell transfer therapies (ACT), specifically for genetically engineered T-cell receptors (TCRs), and chimeric antigen receptor (CAR) T-cells, is target antigen heterogeneity. It is thought that intratumor heterogeneity is one of the leading determinants of therapeutic resistance and treatment ...
arxiv
Microbiology Spectrum, 2022 Antigen-based rapid diagnostic tests (Ag-RDTs) have been widely used for the detection of SARS-CoV-2 during the coronavirus disease 2019 (COVID-19) pandemic.
Jason J. LeBlanc +7 more
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Sequence-Based Nanobody-Antigen Binding Prediction [PDF]
arXiv, 2023 Nanobodies (Nb) are monomeric heavy-chain fragments derived from heavy-chain only antibodies naturally found in Camelids and Sharks. Their considerably small size (~3-4 nm; 13 kDa) and favorable biophysical properties make them attractive targets for recombinant production.
arxiv
Active tuning of synaptic patterns enhances immune discrimination [PDF]
Phys. Rev. Lett. 121, 238101 (2018), 2018 Immune cells learn about their antigenic targets using tactile sense: during recognition, a highly organized yet dynamic motif, named immunological synapse, forms between immune cells and antigen-presenting cells (APCs). Via synapses, immune cells selectively extract recognized antigen from APCs by applying mechanical pulling forces generated by the ...
arxiv +1 more source
Nature CommunicationsStreptococcus pneumoniae (pneumococcus) is a nasopharyngeal commensal and respiratory pathogen. This study characterises the immunoglobulin G (IgG) repertoire recognising pneumococci from birth to 24 months old (mo) in a prospectively-sampled cohort of ...
Nicholas J. Croucher +11 more
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Affinity Discrimination in B cells in Response to Membrane Antigen Requires Kinetic Proofreading [PDF]
arXiv, 2010 B cells signaling in response to antigen is proportional to antigen affinity, a process known as affinity discrimination. Recent research suggests that B cells can acquire antigen in membrane-bound form on the surface of antigen-presenting cells (APCs), with signaling being initiated within a few seconds of B cell/APC contact.
arxiv
Human lymphoma mutations reveal CARD11 as the switch between self-antigen-induced B cell death or proliferation and autoantibody production [PDF]
, 2016 Self-tolerance and immunity are actively acquired in parallel through a poorly understood ability of antigen receptors to switch between signaling death or proliferation of antigenbinding lymphocytes in different contexts.
Domaschenz, Heather +8 more
core +1 more source
Adsorption of organochlorinated pesticides: Adsorption kinetic and adsorption isotherm study
Results in Engineering, 2023 Adsorption of organochlorine pesticides (OCPs) on 4 contrasted activated carbons (ACs) and biochars (BCs) and 5 different basic substances of soil organic matter (SOM) in aqueous media was investigated using adsorption kinetic and isotherm study.
Farida Amutova +8 more
doaj
Identification of Novel Serodiagnostic Signatures of Typhoid Fever Using a Salmonella Proteome Array
Frontiers in Microbiology, 2017 Current diagnostic tests for typhoid fever, the disease caused by Salmonella Typhi, are poor. We aimed to identify serodiagnostic signatures of typhoid fever by assessing microarray signals to 4,445 S.
Thomas C. Darton +23 more
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